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前列腺癌与雄激素调节蛋白的信息分析与基因知识发现

已有 2029 次阅读 2011-2-3 20:34 |个人分类:信息分析|系统分类:论文交流| 前列腺癌

科学家发现一种蛋白质有助控制前列腺癌
FUS/TLS Is a Novel Mediator of Androgen-Dependent Cell-Cycle Progression and Prostate Cancer Growth

http://cancerres.aacrjournals.org/content/71/3/914.abstract

http://www.gopubmed.org/web/gopubmed/WEB1kOWEB10O00h0010009000000h001000j100300.y

信息分析报告  androgen.doc

http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi

Start A-Literature C-Literature B-list Filter Literature
A-query: androgen-regulated proteins and prostat...
C-query: RNA-binding protein
The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 51 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here. The results of this search are saved under id # 30841 and can be accessed from the start page after you leave this session. There are 265 terms on the current B-list (119 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin.

To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.

job id # 30841 started Thu Feb 3 08:23:29 2011
Max_citations: 50000
Stoplist: /var/www/html/arrowsmith_uic/data/stopwords_pubmed
Ngram_max: 3
30841 Search ARROWSMITH A
A_query_raw: androgen-regulated proteins and prostate cancerThu Feb 3 08:25:39 2011

A query = androgen-regulated proteins and prostate cancer started Thu Feb 3 08:25:39 2011
A query resulted in 309 titles
30841 Search ARROWSMITH C
C_query_raw: RNA-binding protein Thu Feb 3 08:26:01 2011

C: RNA-binding protein 126059

A: pubmed_query_A 309

AC: ( androgen-regulated proteins and prostate cancer ) AND ( RNA-binding protein ) 51

C query = RNA-binding protein started Thu Feb 3 08:26:03 2011
C query resulted in 50000 titles
A AND C query resulted in 51 titles
1945 B-terms ready on Thu Feb 3 08:29:25 2011

Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
265 B-terms left after filter executed Thu Feb 3 08:37:34 2011

B-list on Thu Feb 3 08:38:26 2011
1 wnt
2 homeobox
3 amphiregulin
4 beta catenin
5 smad1
6 differentially expressed gene
7 plzf
8 cyclin dependent kinase
9 ets
10 prohibitin
11 tmprss2
12 cancer susceptibility gene
13 androgen response element
14 serial analysis gene
15 c jun
16 nkx3
17 homeobox gene
18 cdna
19 lats2
20 intron
21 p66shc
22 reading frame
23 n myc
24 yb-1
25 cofilin
26 e cadherin
27 erbb2
28 gene family
29 genome wide
30 er beta
31 bmp
32 gata-2
33 c fos
34 talin
35 pur alpha
36 progesterone receptor
37 trinucleotide repeat
38 probasin
39 fgf
40 androgen responsive gene
41 caveolin
42 intronic
43 activating transcription factor
44 protein tyrosine phosphatase
45 clusterin
46 novel gene
47 ndrg1
48 repressor
49 gene encoding
50 cadherin
51 gene expressed
52 metastasis associated gene
53 gene prostate cancer
54 tyrosine phosphatase
55 exon
56 ste20
57 transcription factor
58 first intron
59 responsive gene
60 upstream enhancer
61 homeobox gene nkx3
62 response element
63 er alpha
64 susceptibility gene
65 tgf beta1
66 p glycoprotein
67 cyclin
68 enhancer
69 igf
70 expression gene
71 androgen receptor gene
72 jun
73 cell cycle progression
74 erg
75 androgen regulated gene
76 pc3
77 fibroblast growth factor
78 psa
79 prosaposin
80 eukaryotic gene
81 p44
82 fatty acid synthase
83 tumor suppressor
84 p21
85 diazepam binding inhibitor
86 aminoacyl trna synthetase
87 myc
88 pcgem1
89 reporter gene
90 cyp17
91 androgen receptor
92 udp glucuronosyltransferase
93 analysis gene
94 toll
95 receptor gene
96 mda
97 promoter prostate cancer
98 gene transactivation
99 hedgehog gli
100 g2
101 klk4
102 eaf2
103 spak
104 transmembrane protein
105 nf kb
106 trna
107 heat shock protein
108 g1
109 gene preferentially expressed
110 epidermal growth factor
111 liprin
112 related gene
113 fgf8
114 gene related
115 decoy
116 pak6
117 myosin vi
118 fos
119 trinucleotide

 

 
 


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