http://www.pnas.org/reports/most-read

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1. Biological Sciences - Immunology:

   • Donna L. Mallery,
   • William A. McEwan,
   • Susanna R. Bidgood,
   • Greg J. Towers,
   • Chris M. Johnson,
   • and Leo C. James

   Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21) 2010 107 (46) 19985-19990; published ahead of print November 2, 2010, doi:10.1073/pnas.1014074107
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2. Editorial:

   • Alan Fersht

   The most influential journals: Impact Factor and Eigenfactor 2009 106 (17) 6883-6884; published ahead of print April 20, 2009, doi:10.1073/pnas.0903307106
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3. This Week in PNAS: In This Issue 2010 107 (44) 18743-18744; doi:10.1073/iti4410107
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4. Biological Sciences - Microbiology:

   • Gil Sharon,
   • Daniel Segal,
   • John M. Ringo,
   • Abraham Hefetz,
   • Ilana Zilber-Rosenberg,
   • and Eugene Rosenberg

   From the Cover: Commensal bacteria play a role in mating preference of Drosophila melanogaster 2010 107 (46) 20051-20056; published ahead of print November 1, 2010, doi:10.1073/pnas.1009906107
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5. Physical Sciences - Chemistry - Biological Sciences - Biophysics and Computational Biology:

   • Paul A. Clemons,
   • Nicole E. Bodycombe,
   • Hyman A. Carrinski,
   • J. Anthony Wilson,
   • Alykhan F. Shamji,
   • Bridget K. Wagner,
   • Angela N. Koehler,
   • and Stuart L. Schreiber

   Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles 2010 107 (44) 18787-18792; published ahead of print October 18, 2010, doi:10.1073/pnas.1012741107
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6. Biological Sciences - Ecology - Social Sciences - Sustainability Science:

   • Jason Hill,
   • Erik Nelson,
   • David Tilman,
   • Stephen Polasky,
   • and Douglas Tiffany

   From the Cover: Environmental, economic, and energetic costs and benefits of biodiesel and ethanol biofuels 2006 103 (30) 11206-11210; published ahead of print July 12, 2006, doi:10.1073/pnas.0604600103
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7. This Week in PNAS: In This Issue 2010 107 (46) 19605-19606; doi:10.1073/iti4610107
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8. Physical Sciences - Physics:

   • J. E. Hirsch

   An index to quantify an individual's scientific research output 2005 102 (46) 16569-16572; published ahead of print November 7, 2005, doi:10.1073/pnas.0507655102
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9. Biological Sciences - Biochemistry:

   • Jin Tang and
   • Ronald R. Breaker

   Structural diversity of self-cleaving ribozymes 2000 97 (11) 5784-5789
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10. Commentary:

    • John J. Perona and
    • Javin P. Oza

    Crystal structure of a reverse polymerase 2010 107 (47) 20149-20150; published ahead of print November 15, 2010, doi:10.1073/pnas.1015283107
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11. This Week in PNAS: In This Issue 2010 107 (47) 20145-20146; doi:10.1073/iti4710107
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12. Social Sciences - Sustainability Science:

    • Shahzeen Z. Attari,
    • Michael L. DeKay,
    • Cliff I. Davidson,
    • and Wändi Bruine de Bruin

    From the Cover: Public perceptions of energy consumption and savings 2010 107 (37) 16054-16059; published ahead of print August 16, 2010, doi:10.1073/pnas.1001509107
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13. Social Sciences - Economic Sciences - Biological Sciences - Psychological and Cognitive Sciences:

    • Meghana A. Bhatt,
    • Terry Lohrenz,
    • Colin F. Camerer,
    • and P. Read Montague

    Neural signatures of strategic types in a two-person bargaining game 2010 107 (46) 19720-19725; published ahead of print November 1, 2010, doi:10.1073/pnas.1009625107
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14. Biological Sciences - Microbiology:

    • Mark C. Enright,
    • D. Ashley Robinson,
    • Gaynor Randle,
    • Edward J. Feil,
    • Hajo Grundmann,
    • and Brian G. Spratt

    The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA) 2002 99 (11) 7687-7692; published ahead of print May 21, 2002, doi:10.1073/pnas.122108599
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15. Physical Sciences - Environmental Sciences:

    • James Hansen,
    • Makiko Sato,
    • Reto Ruedy,
    • Ken Lo,
    • David W. Lea,
    • and Martin Medina-Elizade

    Global temperature change 2006 103 (39) 14288-14293; published ahead of print September 25, 2006, doi:10.1073/pnas.0606291103
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16. This Week in PNAS: In This Issue 2010 107 (45) 19133-19134; doi:10.1073/iti4510107
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17. From the Academy:

    • Kathleen Collins,
    • Tyler Jacks,
    • and Nikola P. Pavletich

    From the Academy: The cell cycle and cancer 1997 94 (7) 2776-2778
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18. Biological Sciences - Psychology:

    • Diana Reiss and
    • Lori Marino

    Mirror self-recognition in the bottlenose dolphin: A case of cognitive convergence 2001 98 (10) 5937-5942; published ahead of print May 1, 2001, doi:10.1073/pnas.101086398
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19. Mathematics:

    • John F. Nash, Jr.

    Equilibrium Points in N-Person Games 1950 36 (1) 48-49
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20. Biological Sciences - Medical Sciences:

    • Shyh-Ching Lo,
    • Natalia Pripuzova,
    • Bingjie Li,
    • Anthony L. Komaroff,
    • Guo-Chiuan Hung,
    • Richard Wang,
    • and Harvey J. Alter

    Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors 2010 107 (36) 15874-15879; published ahead of print August 23, 2010, doi:10.1073/pnas.1006901107
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21. Biological Sciences - Neuroscience:

    • Anthony R. Cashmore

    Inaugural Article: The Lucretian swerve: The biological basis of human behavior and the criminal justice system 2010 107 (10) 4499-4504; published ahead of print February 8, 2010, doi:10.1073/pnas.0915161107
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22. Commentary:

    • Ayaz Najafov and
    • Dario R. Alessi

    Uncoupling the Warburg effect from cancer 2010 107 (45) 19135-19136; published ahead of print November 1, 2010, doi:10.1073/pnas.1014047107
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23. Biological Sciences - Microbiology:

    • Stephen Hare,
    • Ann M. Vos,
    • Reginald F. Clayton,
    • Jan W. Thuring,
    • Maxwell D. Cummings,
    • and Peter Cherepanov

    Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance 2010 107 (46) 20057-20062; published ahead of print October 28, 2010, doi:10.1073/pnas.1010246107
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24. Biological Sciences - Genetics:

    • Aravind Subramanian,
    • Pablo Tamayo,
    • Vamsi K. Mootha,
    • Sayan Mukherjee,
    • Benjamin L. Ebert,
    • Michael A. Gillette,
    • Amanda Paulovich,
    • Scott L. Pomeroy,
    • Todd R. Golub,
    • Eric S. Lander,
    • and Jill P. Mesirov

    From the Cover: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles 2005 102 (43) 15545-15550; published ahead of print September 30, 2005, doi:10.1073/pnas.0506580102
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25. Biological Sciences - Cell Biology:

    • David G. Meckes, Jr.,
    • Kathy H. Y. Shair,
    • Aron R. Marquitz,
    • Che-Pei Kung,
    • Rachel H. Edwards,
    • and Nancy Raab-Traub

    Human tumor virus utilizes exosomes for intercellular communication 2010 107 (47) 20370-20375; published ahead of print November 8, 2010, doi:10.1073/pnas.1014194107
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26. Biological Sciences - Psychological and Cognitive Sciences:

    • Martha D. Kaiser,
    • Caitlin M. Hudac,
    • Sarah Shultz,
    • Su Mei Lee,
    • Celeste Cheung,
    • Allison M. Berken,
    • Ben Deen,
    • Naomi B. Pitskel,
    • Daniel R. Sugrue,
    • Avery C. Voos,
    • Celine A. Saulnier,
    • Pamela Ventola,
    • Julie M. Wolf,
    • Ami Klin,
    • Brent C. Vander Wyk,
    • and Kevin A. Pelphrey

    Neural signatures of autism published ahead of print November 15, 2010, doi:10.1073/pnas.1010412107
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27. This Week in PNAS: In This Issue 2010 107 (43) 18233-18234; doi:10.1073/iti4310107
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28. Social Sciences - Psychological and Cognitive Sciences:

    • Daniel Kahneman and
    • Angus Deaton

    High income improves evaluation of life but not emotional well-being 2010 107 (38) 16489-16493; published ahead of print September 7, 2010, doi:10.1073/pnas.1011492107
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29. Biological Sciences - Genetics:

    • Kirill A. Datsenko and
    • Barry L. Wanner

    One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products 2000 97 (12) 6640-6645
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30. Physical Sciences - Environmental Sciences:

    • Susan Solomon,
    • Gian-Kasper Plattner,
    • Reto Knutti,
    • and Pierre Friedlingstein

    Irreversible climate change due to carbon dioxide emissions 2009 106 (6) 1704-1709; published ahead of print January 28, 2009, doi:10.1073/pnas.0812721106
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31. Biological Sciences - Genetics:

    • Michael B. Eisen,
    • Paul T. Spellman,
    • Patrick O. Brown,
    • and David Botstein

    Cluster analysis and display of genome-wide expression patterns 1998 95 (25) 14863-14868
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32. Climate Mitigation and Food Production in Tropical Landscapes Special Feature - Research Articles - Biological Sciences - Sustainability Science:

    • Paul C. West,
    • Holly K. Gibbs,
    • Chad Monfreda,
    • John Wagner,
    • Carol C. Barford,
    • Stephen R. Carpenter,
    • and Jonathan A. Foley

    Climate Mitigation and Food Production in Tropical Landscapes Special Feature: Trading carbon for food: Global comparison of carbon stocks vs. crop yields on agricultural land 2010 107 (46) 19645-19648; published ahead of print November 1, 2010, doi:10.1073/pnas.1011078107
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33. From the Academy - U.S. Frontiers Of Science Symposium:

    • Jenny R. Saffran,
    • Ann Senghas,
    • and John C. Trueswell

    From the Academy: The acquisition of language by children 2001 98 (23) 12874-12875; published ahead of print October 30, 2001, doi:10.1073/pnas.231498898
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34. Biological Sciences - Biochemistry:

    • Jean-Paul Armache,
    • Alexander Jarasch,
    • Andreas M. Anger,
    • Elizabeth Villa,
    • Thomas Becker,
    • Shashi Bhushan,
    • Fabrice Jossinet,
    • Michael Habeck,
    • Gülcin Dindar,
    • Sibylle Franckenberg,
    • Viter Marquez,
    • Thorsten Mielke,
    • Michael Thomm,
    • Otto Berninghausen,
    • Birgitta Beatrix,
    • Johannes Söding,
    • Eric Westhof,
    • Daniel N. Wilson,
    • and Roland Beckmann

    Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-Å resolution 2010 107 (46) 19748-19753; published ahead of print October 27, 2010, doi:10.1073/pnas.1009999107
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35. Social Sciences - Psychology:

    • Susanne M. Jaeggi,
    • Martin Buschkuehl,
    • John Jonides,
    • and Walter J. Perrig

    From the Cover: Improving fluid intelligence with training on working memory 2008 105 (19) 6829-6833; published ahead of print April 28, 2008, doi:10.1073/pnas.0801268105
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36. Biological Sciences - Cell Biology:

    • Esther N. Arwert,
    • Rohit Lal,
    • Sven Quist,
    • Ian Rosewell,
    • Nico van Rooijen,
    • and Fiona M. Watt

    Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate 2010 107 (46) 19903-19908; published ahead of print November 1, 2010, doi:10.1073/pnas.1007404107
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37. Colloquium Paper:

    • H. A. Mooney and
    • E. E. Cleland

    Colloquium Paper: The evolutionary impact of invasive species 2001 98 (10) 5446-5451; doi:10.1073/pnas.091093398
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38. Perspective:

    • Suzanne R. Pfeffer

    How the Golgi works: A cisternal progenitor model 2010 107 (46) 19614-19618; published ahead of print November 2, 2010, doi:10.1073/pnas.1011016107
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39. Physical Sciences - Physics:

    • Eric Brown,
    • Nicholas Rodenberg,
    • John Amend,
    • Annan Mozeika,
    • Erik Steltz,
    • Mitchell R. Zakin,
    • Hod Lipson,
    • and Heinrich M. Jaeger

    From the Cover: Universal robotic gripper based on the jamming of granular material 2010 107 (44) 18809-18814; published ahead of print October 25, 2010, doi:10.1073/pnas.1003250107
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40. Biological Sciences - Medical Sciences:

    • Yasushi Kojima,
    • Ahmet Acar,
    • Elinor Ng Eaton,
    • Kieran T. Mellody,
    • Christina Scheel,
    • Ittai Ben-Porath,
    • Tamer T. Onder,
    • Zhigang C. Wang,
    • Andrea L. Richardson,
    • Robert A. Weinberg,
    • and Akira Orimo

    Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts 2010 107 (46) 20009-20014; published ahead of print November 1, 2010, doi:10.1073/pnas.1013805107
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41. Biological Sciences - Medical Sciences:

    • Mandana Namdar,
    • Gisela Perez,
    • Lang Ngo,
    • and Paul A. Marks

    Selective inhibition of histone deacetylase 6 (HDAC6) induces DNA damage and sensitizes transformed cells to anticancer agents 2010 107 (46) 20003-20008; published ahead of print October 29, 2010, doi:10.1073/pnas.1013754107
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42. Nobel Lecture:

    • Stanley B. Prusiner

    Nobel Lecture: Prions 1998 95 (23) 13363-13383
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43. Colloquium Paper:

    • David Tilman

    Colloquium Paper: Global environmental impacts of agricultural expansion: The need for sustainable and efficient practices 1999 96 (11) 5995-6000
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44. Social Sciences - Economic Sciences:

    • Bruce Headey,
    • Ruud Muffels,
    • and Gert G. Wagner

    Long-running German panel survey shows that personal and economic choices, not just genes, matter for happiness 2010 107 (42) 17922-17926; published ahead of print October 4, 2010, doi:10.1073/pnas.1008612107
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45. Colloquium Paper:

    • Eric Bonabeau

    Colloquium Paper: Adaptive Agents, Intelligence, and Emergent Human Organization: Capturing Complexity through Agent-Based Modeling: Agent-based modeling: Methods and techniques for simulating human systems 2002 99 (Suppl 3) 7280-7287; doi:10.1073/pnas.082080899
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46. Biological Sciences - Evolution:

    • Roy J. Britten

    Transposable element insertions have strongly affected human evolution 2010 107 (46) 19945-19948; published ahead of print November 1, 2010, doi:10.1073/pnas.1014330107
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47. Letter:

    • Jarle Aarstad

    Expert credibility and truth 2010 107 (47) E176; published ahead of print November 8, 2010, doi:10.1073/pnas.1012156107
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48. Social Sciences - Sustainability Science:

    • Brian C. O'Neill,
    • Michael Dalton,
    • Regina Fuchs,
    • Leiwen Jiang,
    • Shonali Pachauri,
    • and Katarina Zigova

    Global demographic trends and future carbon emissions 2010 107 (41) 17521-17526; published ahead of print October 12, 2010, doi:10.1073/pnas.1004581107
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49. Biological Sciences - Genetics:

    • Andrew K. Benson,
    • Scott A. Kelly,
    • Ryan Legge,
    • Fangrui Ma,
    • Soo Jen Low,
    • Jaehyoung Kim,
    • Min Zhang,
    • Phaik Lyn Oh,
    • Derrick Nehrenberg,
    • Kunjie Hua,
    • Stephen D. Kachman,
    • Etsuko N. Moriyama,
    • Jens Walter,
    • Daniel A. Peterson,
    • and Daniel Pomp

    Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors 2010 107 (44) 18933-18938; published ahead of print October 11, 2010, doi:10.1073/pnas.1007028107
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50. Biological Sciences - Population Biology:

    • B. S. Cooper,
    • G. F. Medley,
    • S. P. Stone,
    • C. C. Kibbler,
    • B. D. Cookson,
    • J. A. Roberts,
    • G. Duckworth,
    • R. Lai,
    • and S. Ebrahim

    Methicillin-resistant Staphylococcus aureus in hospitals and the community: Stealth dynamics and control catastrophes 2004 101 (27) 10223-10228; published ahead of print June 25, 2004, doi:10.1073/pnas.0401324101
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