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http://www.nature.com/nm/focus/pain/index.html
The articles in this collection review our progress in understanding the neurobiological basis of pain and the challenges to translate these advances into new analgesics.
There has been substantial progress in understanding the neurobiological basis of pain, but these advances have yet to translate into new and improved analgesics.
Published online: 14 October 2010 | :10.1038/nm1110-1236:10.1038/nm1110-1236
Abstract - | Full Text - Pain, from bench to bedside | (60 ) (60 )
Elie Dolgin
Published online: 14 October 2010 | :10.1038/nm1110-1237:10.1038/nm1110-1237
Animal experiments have produced an explosion of information about pain, but this knowledge has failed to yield new painkillers for use in humans. This abysmal track record has led to calls to overhaul the design of preclinical studies. Elie Dolgin goes to great pains to learn how monitoring rodents' facial expressions and brain activity might offer a more effective and humane way to test drug candidates.
Abstract - | Full Text - Animalgesic effects | (1,380 ) (1,380 )
John T Farrar
Published online: 14 October 2010 | :10.1038/nm.2249:10.1038/nm.2249
Abstract - | Full Text - Advances in clinical research methodology for pain clinical trials | (382 ) (382 )
Michael S Gold & Gerald F Gebhart
Published online: 14 October 2010 | :10.1038/nm.2235:10.1038/nm.2235
Abstract - | Full Text - Nociceptor sensitization in pain pathogenesis | (1,776 ) (1,776 )
Rohini Kuner
Published online: 14 October 2010 | :10.1038/nm.2231:10.1038/nm.2231
Abstract - | Full Text - Central mechanisms of pathological pain | (1,352 ) (1,352 )
Ke Ren & Ronald Dubner
Published online: 14 October 2010 | :10.1038/nm.2234:10.1038/nm.2234
Abstract - | Full Text - Interactions between the immune and nervous systems in pain | (1,414 ) (1,414 )
Irene Tracey
Published online: 14 October 2010 | :10.1038/nm.2229:10.1038/nm.2229
Abstract - | Full Text - Getting the pain you expect: mechanisms of placebo, nocebo and reappraisal effects in humans | (664 ) (664 )
Clifford J Woolf
Published online: 14 October 2010 | :10.1038/nm.2230:10.1038/nm.2230
Abstract - | Full Text - Overcoming obstacles to developing new analgesics | (559 ) (559 )
http://www.gopubmed.org/web/gopubmed/1?WEB1mOWEB10O00d000j10020001000h00100090000
2,157 documents semantically analyzed
1 2 3 | ||
Top Years
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Publications
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2008 |
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199 |
2009 |
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197 |
2007 |
|
180 |
2006 |
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161 |
2010 |
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145 |
2005 |
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136 |
2003 |
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132 |
2004 |
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121 |
2002 |
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100 |
2001 |
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88 |
2000 |
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83 |
1999 |
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64 |
1998 |
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61 |
1997 |
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53 |
1996 |
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51 |
1994 |
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50 |
1995 |
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49 |
1991 |
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35 |
1993 |
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34 |
1990 |
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27 |
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Top Countries
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Publications
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USA |
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566 |
Japan |
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144 |
Italy |
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126 |
Germany |
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125 |
United Kingdom |
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95 |
France |
|
79 |
Turkey |
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61 |
Canada |
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60 |
Spain |
|
51 |
China |
|
49 |
India |
|
44 |
Brazil |
|
40 |
Netherlands |
|
31 |
South Korea |
|
30 |
Switzerland |
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30 |
Sweden |
|
30 |
Denmark |
|
27 |
Australia |
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23 |
Israel |
|
22 |
Greece |
|
19 |
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Top Cities
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Publications
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Boston |
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33 |
London |
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32 |
Ankara |
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26 |
Philadelphia |
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20 |
Milan |
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20 |
Rome |
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19 |
Baltimore |
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18 |
New York City |
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18 |
Seoul, South Korea |
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17 |
Chicago |
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17 |
Tokyo |
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16 |
Barcelona |
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16 |
Paris |
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16 |
Cleveland |
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15 |
Houston |
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15 |
Toronto |
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15 |
Berlin, Germany |
|
13 |
Minneapolis |
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13 |
New Delhi |
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San Diego |
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12 |
1 2 3 ...32 |
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Top Journals
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Publications
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Pain |
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74 |
Eur J Pharmacol |
|
35 |
Arzneimittel-forsch |
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26 |
Anesth Analg |
|
25 |
J Pharmacol Exp Ther |
|
25 |
Anesthesiology |
|
21 |
Gan To Kagaku Ryoho |
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20 |
Spine |
|
19 |
Eur J Pain |
|
15 |
J Clin Oncol |
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15 |
Brit J Pharmacol |
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15 |
Ann Pharmacother |
|
13 |
Am J Gastroenterol |
|
13 |
Deut Med Wochenschr |
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13 |
J Neurosci |
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12 |
Pain Med |
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12 |
J Pain Symptom Manag |
|
12 |
Neuroscience |
|
11 |
Brain Res |
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11 |
Life Sci |
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11 |
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Top Terms
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Publications
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Humans |
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1,611 |
Patients |
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1,118 |
Analgesics |
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997 |
Pain |
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729 |
Middle Aged |
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695 |
Animals |
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675 |
Adult |
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639 |
Anti-Inflammatory Agents, Non-Steroidal |
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576 |
Pain Measurement |
|
536 |
Pharmaceutical Preparations |
|
534 |
Aged |
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521 |
Anti-Inflammatory Agents |
|
428 |
Evaluation Studies as Topic |
|
427 |
Rats |
|
402 |
Analgesics, Opioid |
|
400 |
Diagnosis |
|
323 |
Inflammation |
|
318 |
Treatment Outcome |
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292 |
Morphine |
|
268 |
Mice |
|
239 |
1 2 3 ...422 |
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Top Authors
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Publications
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Ye?ilada E |
|
8 |
Serhan C |
|
8 |
Granados-Soto V |
|
7 |
Küpeli E |
|
6 |
Ferreira S |
|
6 |
Stein C |
|
6 |
Lipton A |
|
6 |
Mantyh P |
|
5 |
Mousa S |
|
5 |
Suzuki T |
|
5 |
Schafer M |
|
5 |
Yaksh T |
|
5 |
Gronert K |
|
5 |
Eisenach J |
|
5 |
Bruera E |
|
5 |
Besson J |
|
5 |
Svensson C |
|
4 |
Jensen T |
|
4 |
Honore P |
|
4 |
Porreca F |
|
4 |
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