Nature463, 495-500 (28 January 2010) | :10.1038/nature08749:10.1038/nature08749; Received 26 August 2009; Accepted 6 December 2009
There is a Retraction (14 October 2010) associated with this document.
Systemic signals regulate ageing and rejuvenation of blood stem cell niches
Shane R. Mayack1, Jennifer L. Shadrach1, Francis S. Kim1 & Amy J. Wagers1
Department of Stem Cell and Regenerative Biology, Harvard University, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Joslin Diabetes Center, One Joslin Place, Boston, Massachusetts 02115, USA
Correspondence to: Amy J. Wagers1 Correspondence and requests for materials should be addressed to A.J.W. (Email: amy.wagers@joslin.harvard.edu).
[PDF] from chri.orgSR Mayack, JL Shadrach, FS Kim, AJ Wagers - Nature, 2010 - nature.com Ageing in multicellular organisms typically involves a progressive decline in cell replacement and repair processes, resulting in several physiological deficiencies, including inefficient muscle repair, reduced bone mass, and dysregulation of blood formation (haematopoiesis). ... Cited by 13 - Related articles - All 10 versions
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