博文
Yamanaka S 的论文被引用情况 2010年生理学或医学诺贝尔奖预测
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日本京都大学 再生医科学研究所干细胞生物学系教授、美国加州旧金山 心血管疾病研究所 高级调查员以及美国加州大学旧金山分校 解剖学教授 Shinya Yamanaka
获奖原因
因发现干细胞和开发诱导多能干细胞而获奖
cell.com [HTML]K Takahashi, S Yamanaka - Cell, 2006 - Elsevier
Differentiated cells can be reprogrammed to an embryonic-like state by transfer of nuclear contents
into oocytes or by fusion with embryonic stem (ES) cells. Little is known about factors that induce
this reprogramming. Here, we demonstrate induction of pluripotent stem cells from mouse ...
Cited by 2552 - Related articles - All 80 versions
cell.com [PDF]… Ohnuki, M Narita, T Ichisaka, K Tomoda, S Yamanaka - Cell, 2007 - Elsevier
Successful reprogramming of differentiated human somatic cells into a pluripotent state would
allow creation of patient- and disease-specific stem cells. We previously reported generation
of induced pluripotent stem (iPS) cells, capable of germline transmission, from mouse ...
Cited by 2016 - Related articles - BL Direct - All 89 versions
Successful reprogramming of differentiated human somatic cells into a pluripotent state would
allow creation of patient- and disease-specific stem cells. We previously reported generation
of induced pluripotent stem (iPS) cells, capable of germline transmission, from mouse ...
Cited by 2016 - Related articles - BL Direct - All 89 versions
ttu.edu [PDF]K Okita, T Ichisaka, S Yamanaka - Nature, 2007 - nature.com
We have previously shown that pluripotent stem cells can be induced from mouse fibroblasts
by retroviral introduction of Oct3/4 (also called Pou5f1), Sox2, c-Myc and Klf4, and subsequent
selection for Fbx15 (also called Fbxo15) expression. These induced pluripotent stem ...
Cited by 1125 - Related articles - BL Direct - All 31 versions
We have previously shown that pluripotent stem cells can be induced from mouse fibroblasts
by retroviral introduction of Oct3/4 (also called Pou5f1), Sox2, c-Myc and Klf4, and subsequent
selection for Fbx15 (also called Fbxo15) expression. These induced pluripotent stem ...
Cited by 1125 - Related articles - BL Direct - All 31 versions
uaslp.mx [PDF]… , K Okita, Y Mochiduki, N Takizawa, S Yamanaka - Nature …, 2007 - nature.com
Direct reprogramming of somatic cells provides an opportunity to generate patient- or
disease-specific pluripotent stem cells. Such induced pluripotent stem (iPS) cells were generated
from mouse fibroblasts by retroviral transduction of four transcription factors: Oct3/4, Sox2, ...
Cited by 646 - Related articles - BL Direct - All 12 versions
Direct reprogramming of somatic cells provides an opportunity to generate patient- or
disease-specific pluripotent stem cells. Such induced pluripotent stem (iPS) cells were generated
from mouse fibroblasts by retroviral transduction of four transcription factors: Oct3/4, Sox2, ...
Cited by 646 - Related articles - BL Direct - All 12 versions
boar.or.kr [PDF]… , M Nakagawa, H Hyenjong, T Ichisaka, S Yamanaka - Science, 2008 - sciencemag.org
... 5. N. Maherali et al., Cell Stem Cell 3, 340 (2008). 6. N. Maherali et al., Cell Stem Cell 1, 55 (2007).
7. WE Lowry et al., Proc. Natl. Acad. Sci. USA 105, 2883 (2008). 8. K. Okita, T. Ichisaka, S.
Yamanaka, Nature 448, 313 (2007). ... 12. S. Yamanaka, Cell Stem Cell 1, 39 (2007). 13. ...
Cited by 369 - Related articles - All 21 versions
... 5. N. Maherali et al., Cell Stem Cell 3, 340 (2008). 6. N. Maherali et al., Cell Stem Cell 1, 55 (2007).
7. WE Lowry et al., Proc. Natl. Acad. Sci. USA 105, 2883 (2008). 8. K. Okita, T. Ichisaka, S.
Yamanaka, Nature 448, 313 (2007). ... 12. S. Yamanaka, Cell Stem Cell 1, 39 (2007). 13. ...
Cited by 369 - Related articles - All 21 versions
[CITATION] Generation of pluripotent stem cells from adult mouse liver and stomach cells
ugr.es [PDF]… T Ichisaka, K Okita, K Takahashi, T Chiba, S Yamanaka - Science, 2008 - AAASCited by 332 - Related articles - All 14 versions
cell.com [HTML]… , K Takahashi, M Maruyama, M Maeda, S Yamanaka - Cell, 2003 - Elsevier
... 1 , Kazutoshi Takahashi 1 , Masayoshi Maruyama 1 , Mitsuyo Maeda 2 and Shinya Yamanaka
Corresponding Author ... Embryonic stem (ES) cells derived from the inner cell mass (ICM) of
blastocysts grow ... In search of a critical factor(s) that underlies pluripotency in both ICM and ...
Cited by 1207 - Related articles - All 25 versions
... 1 , Kazutoshi Takahashi 1 , Masayoshi Maruyama 1 , Mitsuyo Maeda 2 and Shinya Yamanaka
Corresponding Author ... Embryonic stem (ES) cells derived from the inner cell mass (ICM) of
blastocysts grow ... In search of a critical factor(s) that underlies pluripotency in both ICM and ...
Cited by 1207 - Related articles - All 25 versions
stanford.edu [PDF]S Yamanaka - Cell Stem Cell, 2007 - Elsevier
Generating pluripotent stem cells directly from cells obtained from patients is one of the ultimate
goals in regenerative medicine. Two “reprogramming” strategies for the generation of pluripotent
stem cells from somatic cells have been studied extensively: nuclear transfer to oocytes ...
Cited by 200 - Related articles - All 19 versions
Generating pluripotent stem cells directly from cells obtained from patients is one of the ultimate
goals in regenerative medicine. Two “reprogramming” strategies for the generation of pluripotent
stem cells from somatic cells have been studied extensively: nuclear transfer to oocytes ...
Cited by 200 - Related articles - All 19 versions
K Takahashi, K Mitsui, S Yamanaka - Nature, 2003 - nature.com
Embryonic stem (ES) cells are pluripotent cells derived from early mammalian embryos 1, 2 .
Their immortality and rapid growth make them attractive sources for stem cell therapies 3 ;
however, they produce tumours (teratomas) when transplanted, which could preclude ...
Cited by 154 - Related articles - BL Direct - All 9 versions
Embryonic stem (ES) cells are pluripotent cells derived from early mammalian embryos 1, 2 .
Their immortality and rapid growth make them attractive sources for stem cell therapies 3 ;
however, they produce tumours (teratomas) when transplanted, which could preclude ...
Cited by 154 - Related articles - BL Direct - All 9 versions
nih.gov [HTML]… , K Mitsui, M Maeda, H Niwa, S Yamanaka - … and cellular biology, 2003 - Am Soc Microbiol
Embryonic stem (ES) cells are immortal and pluripotent cells derived from early mammalian
embryos. Transcription factor Oct3/4 is essential for self-renewal of ES cells and early mouse
development. However, only a few Oct3/4 target genes have been identified. In this study, ...
Cited by 142 - Related articles - BL Direct - All 8 versions
Embryonic stem (ES) cells are immortal and pluripotent cells derived from early mammalian
embryos. Transcription factor Oct3/4 is essential for self-renewal of ES cells and early mouse
development. However, only a few Oct3/4 target genes have been identified. In this study, ...
Cited by 142 - Related articles - BL Direct - All 8 versions
nih.gov [HTML]… , H Kiyama, K Yonezawa, S Yamanaka - … and cellular biology, 2004 - Am Soc Microbiol
TOR is a serine-threonine kinase that was originally identified as a target of rapamycin in Saccharomyces
cerevisiae and then found to be highly conserved among eukaryotes. In Drosophila
melanogaster, inactivation of TOR or its substrate, S6 kinase, results in reduced cell size ...
Cited by 133 - Related articles - BL Direct - All 8 versions
Cited by 1722 - Related articles - BL Direct - All 33 versions
TOR is a serine-threonine kinase that was originally identified as a target of rapamycin in Saccharomyces
cerevisiae and then found to be highly conserved among eukaryotes. In Drosophila
melanogaster, inactivation of TOR or its substrate, S6 kinase, results in reduced cell size ...
Cited by 133 - Related articles - BL Direct - All 8 versions
uci.edu [PDF]K Takahashi, K Okita, M Nakagawa, S Yamanaka - Nature protocols, 2007 - nature.com
Clinical application of embryonic stem (ES) cells faces difficulties regarding use of embryos,
as well as tissue rejection after implantation. One way to circumvent these issues is to generate
pluripotent stem cells directly from somatic cells. Somatic cells can be reprogrammed to ...
Cited by 131 - Related articles - BL Direct - All 5 versions
Clinical application of embryonic stem (ES) cells faces difficulties regarding use of embryos,
as well as tissue rejection after implantation. One way to circumvent these issues is to generate
pluripotent stem cells directly from somatic cells. Somatic cells can be reprogrammed to ...
Cited by 131 - Related articles - BL Direct - All 5 versions
[CITATION] Induced pluripotent stem cell lines derived from human somatic cells
fhcrc.org [PDF]… -Otto, J Antosiewicz-Bourget, JL Frane, S Tian, J Nie, … - Science, 2007 - AAASCited by 1722 - Related articles - BL Direct - All 33 versions
ahajournals.org [HTML]… Teranishi, K Okita, B Kim, S Matsuoka, S Yamanaka, … - Circulation, 2008 - Am Heart Assoc
From the Laboratory of Stem Cell Differentiation, Stem Cell Research Center, Institute for Frontier
Medical Sciences, Kyoto University, Kyoto, Japan (GN, HU, MT, JKY); Department of Stem Cell
Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan (KO, SY); ...
Cited by 106 - Related articles - All 5 versions
From the Laboratory of Stem Cell Differentiation, Stem Cell Research Center, Institute for Frontier
Medical Sciences, Kyoto University, Kyoto, Japan (GN, HU, MT, JKY); Department of Stem Cell
Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan (KO, SY); ...
Cited by 106 - Related articles - All 5 versions
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