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James E. Till的论文被引用情况（2010年生理学或医学诺贝尔奖得主预测）
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加拿大安大略癌症研究所 高级科学家 James E. Till
获奖原因
因在 DNA 因发现干细胞和开发诱导多能干细胞而获奖
pnas.org [PDF]JE Till, EA McCulloch, L Siminovitch - Proceedings of the National …, 1964 - ncbi.nlm.nih.gov
Normal mammalian hemopoietic tissue produces a continuous supply of dif- ferentiated blood
cells whose functions are essential for life. These functional cells have limited life spans and
are incapable of self-renewal. For example, erythro- cytes lack nuclei and thus, though ...
Cited by 565 - Related articles - All 11 versions
Normal mammalian hemopoietic tissue produces a continuous supply of dif- ferentiated blood
cells whose functions are essential for life. These functional cells have limited life spans and
are incapable of self-renewal. For example, erythro- cytes lack nuclei and thus, though ...
Cited by 565 - Related articles - All 11 versions
… Worton, EA McCulloch, JE Till - Journal of Cellular …, 1969 - interscience.wiley.com
ABSTRACT Mouse bone marrow cells in suspension were separated into a number of fractions
on the basis of cell density by equilibrium density gradient centrifugation, or on the basis of cell
size by velocity sedimentation. After each type of separation, the cells from the various ...
Cited by 359 - Related articles - All 2 versions
ABSTRACT Mouse bone marrow cells in suspension were separated into a number of fractions
on the basis of cell density by equilibrium density gradient centrifugation, or on the basis of cell
size by velocity sedimentation. After each type of separation, the cells from the various ...
Cited by 359 - Related articles - All 2 versions
[CITATION] Hemopoietic stem cell differentiation.
1: Biochim Biophys Acta. 1980 Nov 26;605(4):431-59. Hemopoietic stem cell differentiation. Till
JE, McCulloch EA. Publication Types: Research Support, Non-US Gov't; Review. Mesh Terms:
Animals; Antigens, Surface/immunology; Cell Differentiation*; Cell Division; ...
Cited by 242 - Related articles - All 3 versions
WJ Mackillop, A Ciampi, JE Till, RN … - Journal of the National …, 1983 - ncbi.nlm.nih.gov
A simple stem cell model of human tumor growth is presented. Three tumor cell populations are
predicted: stem, transitional, and end cells. The properties of these cells are discussed in terms
of their behavior in currently available technologies for investigation of cell kinetics and ...
Cited by 140 - Related articles - All 2 versions
A simple stem cell model of human tumor growth is presented. Three tumor cell populations are
predicted: stem, transitional, and end cells. The properties of these cells are discussed in terms
of their behavior in currently available technologies for investigation of cell kinetics and ...
Cited by 140 - Related articles - All 2 versions
utoronto.ca [PDF]… , EA McCulloch, JE Till… - Journal of Cellular and …, 1963 - tspace.library.utoronto.ca
... Gurney, CW, LG Lajtha and R. Oliver 1962 A method for investigation of stem-cell kinetics.
Brit. J. Haemat., 8: 461-466. McCulloch, EA, and JE Till 1962 The sensitivity of cells from
normal mouse bone marrow to gamrna radiation in vitro and in vivo. ...
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... Gurney, CW, LG Lajtha and R. Oliver 1962 A method for investigation of stem-cell kinetics.
Brit. J. Haemat., 8: 461-466. McCulloch, EA, and JE Till 1962 The sensitivity of cells from
normal mouse bone marrow to gamrna radiation in vitro and in vivo. ...
Cited by 511 - Related articles - View as HTML - All 5 versions
hematologylibrary.org [PDF]… , EA McCulloch, L Siminovitch, JE Till - …, 1965 - bloodjournal.hematologylibrary.org
... By A. J. BECKER, EA MCCULLOCH, L. SIMIN0vITcH AND J. E. TILL ... These specialized cells
are con- tinuously replaced by tile differentiation of descendants of progenitor or stem cells, which
possess capacity for extensive proliferation and self-renewal.12-3'4 ...
Cited by 483 - Related articles - All 8 versions
... By A. J. BECKER, EA MCCULLOCH, L. SIMIN0vITcH AND J. E. TILL ... These specialized cells
are con- tinuously replaced by tile differentiation of descendants of progenitor or stem cells, which
possess capacity for extensive proliferation and self-renewal.12-3'4 ...
Cited by 483 - Related articles - All 8 versions
rupress.org [PDF]AM Wu, JE Till, L Siminovitch, EA … - The Journal of …, 1968 - jem.rupress.org
... BY AM WU,$ BM, JE TILL, PH.D., L. SIMINOVITCH, ProD., Am) EA McCULLOCH, MD (From the
Departments of Medicine and ... mouse hematopoietic colony- forming stem ceils can differentiate
along both erythropoietic and granulocytic lines (1). This class of stem cells is present ...
Cited by 308 - Related articles - All 11 versions
... BY AM WU,$ BM, JE TILL, PH.D., L. SIMINOVITCH, ProD., Am) EA McCULLOCH, MD (From the
Departments of Medicine and ... mouse hematopoietic colony- forming stem ceils can differentiate
along both erythropoietic and granulocytic lines (1). This class of stem cells is present ...
Cited by 308 - Related articles - All 11 versions
rupress.org [PDF]RG Worton, EA McCulloch, JE Till - Journal of Experimental …, 1969 - jem.rupress.org
Two key properties of hemopoietic stem cells are their capacity for self- renewal and their capacity
for differentiation. The stem ceils in mouse hemo- poietic tissues that may be detected by their
ability to form macroscopic splenic colonies possess both these properties, but express ...
Cited by 99 - Related articles - All 8 versions
Two key properties of hemopoietic stem cells are their capacity for self- renewal and their capacity
for differentiation. The stem ceils in mouse hemo- poietic tissues that may be detected by their
ability to form macroscopic splenic colonies possess both these properties, but express ...
Cited by 99 - Related articles - All 8 versions
pnas.org [PDF]AM Wu, L Siminovitch, JE Till, EA McCulloch - Proceedings of the National …, 1968 - JSTOR
The spleen colony technique' has proved to be a useful tool for the enumera- tion of hemopoietic
stem cells in the mouse and for the study of their properties. However, since the method depends
on colony formation in the spleens of heavily irradiated' or genetically anemic2 mice, it ...
Cited by 84 - Related articles - All 8 versions
The spleen colony technique' has proved to be a useful tool for the enumera- tion of hemopoietic
stem cells in the mouse and for the study of their properties. However, since the method depends
on colony formation in the spleens of heavily irradiated' or genetically anemic2 mice, it ...
Cited by 84 - Related articles - All 8 versions
AM Wu, JE Till, L Siminovitch, EA … - Journal of Cellular …, 1967 - interscience.wiley.com
... teristics of the metaphase cells were not determined, it is possible that the marked cells in both
tissues could have differenti- ated along the same pathway and if this were the case, they would
have been de- rived from unipotent stem cells. Becker, McCulloch and Till ('63), Fow ...
Cited by 224 - Related articles - All 2 versions
... teristics of the metaphase cells were not determined, it is possible that the marked cells in both
tissues could have differenti- ated along the same pathway and if this were the case, they would
have been de- rived from unipotent stem cells. Becker, McCulloch and Till ('63), Fow ...
Cited by 224 - Related articles - All 2 versions
hematologylibrary.org [PDF]NN Iscove, JS Senn, JE Till, EA … - Blood, 1971 - bloodjournal.hematologylibrary.org
... Page 4. 4 ISCOVE ET AL. 7. Senn, JS, McCulloch, E. A., and Till, Table 3.-Marrow From Patients
With Acute Myelogenous Leukemia in Relapse Patient0 Colonies/105 Nucleated Marrow Cells
Tested Conditioned Medium No Conditioned Medium 1 18,24,21,31 0,0,0,0 ...
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... Page 4. 4 ISCOVE ET AL. 7. Senn, JS, McCulloch, E. A., and Till, Table 3.-Marrow From Patients
With Acute Myelogenous Leukemia in Relapse Patient0 Colonies/105 Nucleated Marrow Cells
Tested Conditioned Medium No Conditioned Medium 1 18,24,21,31 0,0,0,0 ...
Cited by 428 - Related articles - View as HTML - All 4 versions
JE Till - Journal of Cellular Physiology, 1982 - interscience.wiley.com
The stem cell concept continues to be very useful both for studies on cellular differentiation and
for studies on neoplasia. At present the concept is being enlarged to include consideration of
a new aspect: stem cell genetics, at the molecular level. Some questions are still to be ...
Cited by 63 - Related articles - All 3 versions
The stem cell concept continues to be very useful both for studies on cellular differentiation and
for studies on neoplasia. At present the concept is being enlarged to include consideration of
a new aspect: stem cell genetics, at the molecular level. Some questions are still to be ...
Cited by 63 - Related articles - All 3 versions
JE Dick, MC Magli, D Huszar, RA Phillips, A Bernstein - Cell, 1985 - Elsevier
... B. Clarkson, PA Marks, and JE Till, eds. (Cold Spring Harbor, New York: Cold Spring Harbor
Laboratory), pp. 109-120. Phillips, RA (1985). Comparison of different assays for multipotent
hematopoietic stem cells. In Mediators in Cell Growth and Differentia- tion. ...
Cited by 455 - Related articles - All 3 versions
... B. Clarkson, PA Marks, and JE Till, eds. (Cold Spring Harbor, New York: Cold Spring Harbor
Laboratory), pp. 109-120. Phillips, RA (1985). Comparison of different assays for multipotent
hematopoietic stem cells. In Mediators in Cell Growth and Differentia- tion. ...
Cited by 455 - Related articles - All 3 versions
utoronto.ca [PDF]EA McCulloch, L Siminovitch, JE Till - Science, 1964 - sciencemag.org
... Our results sup- port the suggestion (18) that the "stem cells" responding to erythropoietin (19)
are not identical with the "stem cells" that give rise to spleen colonies. EA MCCULLOCH L.
SIMINOVITCH JE TILL Department of Medical Biophysics, University of Toronto, and ...
Cited by 271 - Related articles - All 6 versions
... Our results sup- port the suggestion (18) that the "stem cells" responding to erythropoietin (19)
are not identical with the "stem cells" that give rise to spleen colonies. EA MCCULLOCH L.
SIMINOVITCH JE TILL Department of Medical Biophysics, University of Toronto, and ...
Cited by 271 - Related articles - All 6 versions
uky.edu [PDF]GJ Spangrude, S Heimfeld, IL Weissman … - Science(Washington), 1988 - elegans.uky.edu
... Perhaps this model will prove sufficient for experiments designed to identify and isolate human
hematopoietic stem cells. If so, the use of these cells in bone marrow transplantation, as targets
for gene insertion therapy, and for the study of the ... 3. JE Till and EA McCulloch, Rad. ...
Cited by 1692 - Related articles - View as HTML - All 8 versions
... Perhaps this model will prove sufficient for experiments designed to identify and isolate human
hematopoietic stem cells. If so, the use of these cells in bone marrow transplantation, as targets
for gene insertion therapy, and for the study of the ... 3. JE Till and EA McCulloch, Rad. ...
Cited by 1692 - Related articles - View as HTML - All 8 versions
hematologylibrary.org [PDF]EA McCulloch, L Siminovitch, JE Till, ES … - …, 1965 - bloodjournal.hematologylibrary.org
... The spleen-colony method of assaying for the proliferative capacity of cells derived from
hemopoietic tissue has been described elsewhere, (Till and McCulloch7) and (McCulloch and
Till8). ... be hemopoietic stem cells have been published elsewhere (Siminovitch et al.9). ...
Cited by 261 - Related articles - All 6 versions
... The spleen-colony method of assaying for the proliferative capacity of cells derived from
hemopoietic tissue has been described elsewhere, (Till and McCulloch7) and (McCulloch and
Till8). ... be hemopoietic stem cells have been published elsewhere (Siminovitch et al.9). ...
Cited by 261 - Related articles - All 6 versions
uniss.it [PDF]MF Pittenger, AM Mackay, SC Beck, RK Jaiswal, R … - Science, 1999 - sciencemag.org
... Natl. Acad. Sci. USA 95, 13726 (1998). 2. JE Till and EA McCulloch, Radiat. Res. 14, 213 (1961);
BI Lord, in Stem Cells, CS Potten, Ed. (Academic Press, New York, 1996), pp. 401–422; CI Civin
et al., J. Immunol. 133, 157 (1984). 3. SA Kuznetsov et al., J. Bone Miner. Res. ...
Cited by 8519 - Related articles - BL Direct - All 13 versions
... Natl. Acad. Sci. USA 95, 13726 (1998). 2. JE Till and EA McCulloch, Radiat. Res. 14, 213 (1961);
BI Lord, in Stem Cells, CS Potten, Ed. (Academic Press, New York, 1996), pp. 401–422; CI Civin
et al., J. Immunol. 133, 157 (1984). 3. SA Kuznetsov et al., J. Bone Miner. Res. ...
Cited by 8519 - Related articles - BL Direct - All 13 versions
hematologylibrary.org [PDF]MD Minden, JE Till, EA McCulloch - Blood, 1978 - bloodjournal.hematologylibrary.org
... By MD Minden, JE Till, and EA McCulloch Peripheral blood from patients with acute myeloblastic
leukemia (AML) contains cells capable of giving rise to colonies in culture when stimulated by
media conditioned by leukocytes (1CM) in the presence of phyto- hemagglutinin (PH ...
Cited by 111 - Related articles - All 3 versions
... By MD Minden, JE Till, and EA McCulloch Peripheral blood from patients with acute myeloblastic
leukemia (AML) contains cells capable of giving rise to colonies in culture when stimulated by
media conditioned by leukocytes (1CM) in the presence of phyto- hemagglutinin (PH ...
Cited by 111 - Related articles - All 3 versions
nih.gov [PDF]EA McCulloch, JE Till - The American Journal of Pathology, 1971 - ncbi.nlm.nih.gov
HEMOPOTETIC SrEM CELLS stand at the beginning of processes of exponential growth and
cellular differentiation. They providethe origins from which marrow recovers after injury or grows
after trans- plantation. When stem cells are damaged by injury or disease, the effects are ...
Cited by 36 - Related articles - All 5 versions
HEMOPOTETIC SrEM CELLS stand at the beginning of processes of exponential growth and
cellular differentiation. They providethe origins from which marrow recovers after injury or grows
after trans- plantation. When stem cells are damaged by injury or disease, the effects are ...
Cited by 36 - Related articles - All 5 versions
[CITATION] Regulation of hemopoietic stem cells
Cited by 33 - Related articles
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