… Wu, HY Mo, MF Hong, MC King, Z Chen, YX Zeng - Nature genetics, 2002 - nature.com ... 8 These authors contributed equally to this work. Correspondence should be addressed to Yi-Xin Zeng yxzeng@gzsums.edu.cn. Nasopharyngealcarcinoma (NPC) occurs with high frequency in Asian populations, especially among people of Cantonese ancestry. ... Cited by 127 - Related articles - BL Direct - All 4 versions
aacrjournals.org[HTML]J Wang, LP Guo, LZ Chen, YX Zeng, SH Lu - Cancer research, 2007 - AACR The concept of cancer stem cell (CSC) was introduced many years ago to explain tumor cell heterogeneity, and recent studies suggest that CSC may be responsible for tumorigenesis and contribute to some individuals' resistance to cancer therapy. Recently, CSC have been ... Cited by 118 - Related articles - BL Direct - All 8 versions
aacrjournals.org[HTML]… YF Xia, LW Fu, WL Huang, GP Dimri, V Band, YX Zeng - Cancer research, 2006 - AACR Nasopharyngeal carcinoma is a common cancer in southern China (1–3). The etiologic factors associated with nasopharyngeal carcinoma are believed to be genetic susceptibility, EBV infection, and other environmental factors (1–3). However, the precise genetic changes ... Cited by 101 - Related articles - BL Direct - All 4 versions
… , MH Hong, SM Cao, WY Mai, HQ Min, YX Zeng - Cancer, 2000 - interscience.wiley.com 1 Department of Nasopharyngeal Carcinoma, Can- cer Center, Sun Yat-sen University of Medical Sci- ences, Guangzhou, People's Republic of China. 2 Central Laboratory, Cancer Center, Sun Yat-sen University of Medical Sciences, Guangzhou, Peo- ple's Republic of China. 3 ... Cited by 76 - Related articles - BL Direct - All 3 versions
… Zhu, ZC Liu, BF Xie, ZM Li, GK Feng, D Yang, YX Zeng - Cancer letters, 2001 - Elsevier Nasopharyngeal carcinoma (NPC), which occurs with a high incidence in southern China and southeast Asia, is of epithelial origin with overexpression of EGF receptor. To study the effect of inhibition of EGFR signaling on nasopharyngeal carcinoma cell proliferation and cell ... Cited by 48 - Related articles - All 8 versions
… Feng, QX Long, XZ Wang, YX Zeng - … Journal of Cancer, 2003 - interscience.wiley.com Nonrandom allelic loss on chromosome 3p is a common event in nasopharyngeal carcinoma (NPC) with the implica- tion that certain tumor suppressor gene(s) in this region are involved in the pathogenesis of these tumors. The BLU gene, located at 3p21.3, has recently been ... Cited by 45 - Related articles - BL Direct - All 5 versions
YX Zeng, WH Jia - Seminars in cancer biology, 2002 - Elsevier Nasopharyngeal carcinoma (NPC) has a striking geographical and ethnical distribution. It occurs with high frequency in southern China and Southeast Asia. Family clustering was also observed in NPC and a typical family with 15 NPC cases was introduced in this paper. ... Cited by 39 - Related articles - BL Direct - All 5 versions
… XQ Liu, J Lin, TY Chen, QS Feng, YX Zeng - … journal of cancer, 2002 - ncbi.nlm.nih.gov 1. Ai Zheng. 2002 Oct;21(10):1047-50. [Mutation analysis of KLF6 gene in human nasopharyngealcarcinomas] [Article in Chinese] Chen HK, Liu XQ, Lin J, Chen TY, Feng QS, ZengYX. Cancer Center, Sun Yat-sen University, Guangzhou 510060, PR China. ... Cited by 36 - Related articles
aacrjournals.org[HTML]W Xiong, ZY Zeng, JH Xia, K Xia, SR Shen, XL Li, DX … - Cancer research, 2004 - AACR Nasopharyngeal carcinoma (NPC) poses one of the serious health problems in southern Chinese, with an incidence rate ranging from 15 to 50/100,000. Chromosome translocation t(1;3) and frequent loss of heterogeneity on short arms of chromosome 3 and 9 have been ... Cited by 76 - Related articles - BL Direct - All 7 versions
biomedcentral.com[HTML]… , MY Huang, JH Hou, D Xie, YX Zeng, JY … - Journal of …, 2008 - biomedcentral.com Expression of survivin and VEGF were significantly associated with TNM stage, T-stage and metastasis of NPC. The patients with survivin and VEGF over-expression presented lower 5-year survival rate, as compared to those of low-expression (42.32% vs. 70.54%, 40.1% ... Cited by 29 - Related articles - Cached - All 12 versions
… , MZ Li, JH Hou, LW Fu, WL Huang, YX Zeng, MS Zeng - Cancer letters, 2006 - Elsevier The present study was aimed to determine twist expression in nasopharyngeal carcinoma (NPC) and to investigate the clinicopathological significance in the progress of NPC. Semiquantitative RT-PCR and Western blotting were carried out to investigate the expression of Twist in ... Cited by 29 - Related articles - All 4 versions
biomedcentral.com[HTML]… , L Deng, LF Hu, I Ernberg, YX Zeng, DX Lin, JY … - … cancer, 2006 - biomedcentral.com Nasopharyngeal carcinoma (NPC) is one of the most common cancers in southern China. In addition to environmental factors such as Epstein-Barr virus infection and diet, genetic susceptibility has been reported to play a key role in the development of this disease. The x-ray repair ... Cited by 29 - Related articles - Cached - All 8 versions
daifumd.com[PDF]… Deng, LX Lu, SM Huang, ZF Zeng, CG Lin, HH … - International Journal of …, 2004 - Elsevier A total of 49 patients with locoregional recurrent carcinoma in the nasopharynx were treated with IMRT between January 2001 and February 2002 at the Sun Yat-Sen University Cancer Center, Guangzhou, China. The average time to the nasopharyngeal recurrence was ... Cited by 70 - Related articles - All 4 versions
… , QS FENG, ZF REN, I ERNBERG, LF HU, YX ZENG - Anticancer …, 2001 - cat.inist.fr Sixty-one human nasopharyngeal carcinomas (NPC) were examined by allelotype analysis for the purposes of detecting potential association between loss of heterozygosity (LOH), clinicopathological parameters and Epstein-Barr virus (EBV) infection. LOH was performed using 257 ... Cited by 28 - Related articles - BL Direct - All 2 versions
biomedcentral.com[HTML]… Li, X Lin, FL Wen, HO Adami, Y Zeng, YX Zeng - … cancer, 2006 - biomedcentral.com Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world but is common in southern China. A recent report from the Hong Kong Cancer Registry, a high-risk area for NPC in southern China, showed that incidence rate decreased by 29% for males and by 30% ... Cited by 28 - Related articles - Cached - All 11 versions
WH Jia, A Collins, YX Zeng, BJ Feng, XJ Yu, … - European Journal of …, 2004 - nature.com The striking geographical and ethnic distribution of nasopharyngeal carcinoma (NPC) suggests the involvement of genetic and environmental factors in NPC development. The purpose of this study is to investigate the fit of single gene, polygenic and multifactorial models to the ... Cited by 23 - Related articles - All 8 versions
… Huang, XJ Yu, QS Feng, P Huang, JJ Chen, YX Zeng - Cancer letters, 2002 - Elsevier Development of nasopharyngeal carcinoma (NPC) is closely associated with Epstein–Barr virus (EBV) infection. However, NPC occurs with a marked geographic and racial distribution, whereas EBV infection is ubiquitous in the world. This leads to a question whether certain subtypes ... Cited by 26 - Related articles - All 7 versions
nih.gov[HTML]… Zhang, XJ Yu, HM Wang, I Ernberg, YX Zeng - Journal of …, 2005 - Am Soc Microbiol To date, the only entire Epstein-Barr virus (EBV) genomic sequence available in the database is the prototype B95.8, which was derived from an individual with infectious mononucleosis. A causative link between EBV and nasopharyngeal carcinoma (NPC), a disease with a ... Cited by 22 - Related articles - BL Direct - All 10 versions
Zhu, ZC Liu, BF Xie, GK Feng, YX Zeng - Cancer letters, 2003 - Elsevier Ceramide mediates differentiation, growth arrest, apoptosis, proliferation, cytokine biosynthesis and secretion, and a variety of other cellular functions. However, little is known regarding ceramide signaling linked to the cell cycle. In the present study, the effect of ceramide on cell cycle ... Cited by 19 - Related articles - All 6 versions
… Hu, A Li, RH Zhang, HQ Mai, JC Xia, LZ Chen, YX Zeng - Cancer letters, 2004 - Elsevier Epstein-Barr virus (EBV) has been suggested to be involved in pathogenesis of nasopharyngeal carcinoma (NPC). However, EBV infection is ubiquitous, whereas NPC occurs with strong geographic and racial distribution. Whether a substrain of EBV contributes to this phenomenon ... Cited by 18 - Related articles - All 4 versions
biomedcentral.com[HTML]… , MS Zeng, GP Shen, JH Hou, YX Zeng - Journal of …, 2005 - biomedcentral.com Nasopharyngeal carcinoma (NPC) is a tumor derived from epithelial cells and Epstein-Barr virus infection has been reported to be a cause of this disease. Chemokine receptor CXCR4 was found to be involved in HIV infection and was highly expressed in human malignant breast ... Cited by 18 - Related articles - Cached - All 15 versions
Y Zeng, MG Jan, Q Zhang, LG Zhang, … - … Journal of Cancer, 1982 - interscience.wiley.com ...ZENG, Y., LIU, Y .X., LIN, ZY, ZHEN, SW, WEI, JN, ZHU, JS, and ZAI, HJ, Application of immunoenzymatic method and immuno-autoradiographic method for the mass survey of nasopharyngealcarcinoma. Chinese J . Oncol., 1, 2-7 (1979~). ZENG, Y., LIU, YX, LIN, ZR, ZHEN, ... Cited by 117 - Related articles - All 2 versions
… Huang, QC Liu, Y Li, PH Wu, YX Zeng … - … Journal of Cancer, 2006 - interscience.wiley.com The growth and metastasis of nasopharyngeal carcinoma (NPC), one of the most common cancers in southern China, is closely related to neovascularization. Here, we examined whether intra- tumoral delivery of endostatin gene could lead to long-term local expression of ... Cited by 16 - Related articles - BL Direct - All 3 versions
aacrjournals.org[HTML]… , XJ Yu, LZ Chen, QS Feng, YY Shugart, YX Zeng - Cancer Epidemiology …, 2006 - AACR Nasopharyngeal carcinoma (NPC) occurs sporadically in Western countries, but is endemic in southern China and Southeast Asia, with incidence rates from 15 to 50 per 100,000 (1, 2). Etiologic studies have shown that NPC is a complex disease involving genetic, EBV ... Cited by 16 - Related articles - BL Direct - All 4 versions
beyotime.com[PDF]… Kong, CN Qian, YX Zeng, MS Zeng, DF Liao, LB … - Biochemical and …, 2008 - Elsevier 5-Fluorouracil (5-FU) is an important chemotherapeutic agent for nasopharyngeal carcinoma (NPC). However, drug resistance may occur after several cycles of 5-FU-based chemotherapy. The oncogene B-cell-specific Moloney murine leukemia virus insertion ... Cited by 17 - Related articles - All 7 versions
aacrjournals.org[HTML]… Mai, SM Cao, MZ Li, HD Qin, YX Zeng, MS Zeng - Clinical cancer …, 2007 - AACR Results: Reverse transcription-PCR and Western blot showed that the expression level of CENP-H was higher in NPC cell lines and in immortalized nasopharyngeal epithelial cells than in the normal nasopharyngeal epithelial cell line at both transcriptional and translational ... Cited by 16 - Related articles - BL Direct - All 5 versions
biomedcentral.com[HTML]… , MZ Zheng, ZY Hu, LZ Cheng, YX Zeng - Journal of …, 2006 - biomedcentral.com Nasopharyngeal carcinoma (NPC) is an epithelial cancer, the histology of which ranges from well-differentiated, keratinizing squamous cell carcinoma to undifferentiated, non-keratinizing carcinoma according to the World Health Organization (WHO) histological classification of ... Cited by 13 - Related articles - Cached - All 16 versions
ZY Zeng, YH Zhou, WL Zhang, W Xiong, SQ Fan, XL Li … - Human pathology, 2007 - Elsevier Nasopharyngeal carcinoma (NPC) is a particularly common malignant disease in areas of south China and Southeast Asia. To characterize the gene expression profiling of NPC, we detected the gene expression profiles in 22 NPC and 10 nontumor nasopharyngeal epithelial ... Cited by 26 - Related articles - All 5 versions
… , XJ YU, JT LI, LF HU, I ERNBERG, YX ZENG - International journal of …, 2000 - cat.inist.fr Nasopharyngeal carcinoma (NPC) is one of the most common malignant tumors in Southern China, especially in the Guangdong area. To demonstrate a comprehensive profile of loss of heterozygosity (LOH) in NPC, we applied a large panel of 382 microsatellite ... Cited by 54 - Related articles - BL Direct - All 4 versions
… Y Fang, BJ Huang, QW Liang, QL Wu, YX Zeng - Cancer genetics and …, 2002 - Elsevier HER2 (c-erbB-2) has been suggested to be a prognostic factor in a variety of human cancers including breast, gastric and ovarian cancers. This study is therefore designed to identify changes of HER2 in nasopharyngeal carcinoma (NPC), an epithelia-derived malignancy with ... Cited by 13 - Related articles - All 8 versions
aacrjournals.org[HTML]… Chen, QS Feng, RH Zhang, XJ Yu, MZ Zheng, YX Zeng - Cancer research, 2006 - AACR Nasopharyngeal carcinoma is a human malignancy derived from epithelia cells and is rare in most parts of the world but is common in Southern China, Southeast Asian, and in some North African countries (1). Nasopharyngeal carcinoma represents a superb model of gene- ... Cited by 10 - Related articles - BL Direct - All 5 versions
nih.gov[HTML]… , L Zhang, M Zeng, M Li, W Huang, X Wang, YX Zeng, … - PLoS One, 2007 - ncbi.nlm.nih.gov Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV) associated malignancy with high prevalence in Southern Chinese. In order to assess whether defects of EBV-specific immunity may contribute to the tumor, the phenotype and function of circulating T-cells and tumor ... Cited by 12 - Related articles - All 8 versions
Y Zeng, JM Zhong, LY Li, PZ Wang, H Tang, YR … - …, 1983 - content.karger.com ... Follow-Up Studies on Epstein - Barr virus IgA/VCA Antibody-Positive Persons in Zangwu County, China Y. Zeng a , JM Zhong b , LY Li b , PZ Wang c , H. Tang b , YR Ma c , JS Zhu b , WJ Pan b , YX Liu d , ZN ... Epstein-Barr virus; IgA/VCA antibody; Nasopharyngealcarcinoma. ... Cited by 55 - Related articles - All 5 versions
… Law, D Chua, YX Zeng, SW Tsao, EJ … - … Journal of Cancer, 2008 - interscience.wiley.com By using a functional complementation approach, suppression of tumorigenicity was observed after transfer of intact or truncated copies of chromosome 3 into a nasopharyngeal carcinoma (NPC) HONE1 cell line. The extra exogenous chromosome 3 in the microcell hybrids ... Cited by 13 - Related articles - BL Direct - All 5 versions
umich.edu[PDF]… , J Sun, J Wang, D Yang, YX Zeng - … Journal of Cancer, 2008 - interscience.wiley.com Nasopharyngeal carcinoma (NPC) is a common malignant tumor in South China. It has been reported that overexpression of antia- poptotic Bcl-2 family proteins in NPC has caused the lack of long- term efficacy of conventional therapies. Apogossypolone (ApoG2), a novel small- ... Cited by 10 - Related articles - All 5 versions
cellbiolint.org[PDF]… Li, HM Wang, YX He, ML Zheng, HL Yang, WL … - Cell biology …, 2006 - Elsevier The p21 antisense oligodeoxynucleotides (p21 AS ODNs) and the random control oligodeoxynucleotides (p21 RD ODNs) were synthesized. p21 AS ODNs sequence: 5′-TGTCATGCTGGTCTGCCGCC-3′; p21 RD ODNs sequence: 5′- ... Cited by 18 - Related articles - BL Direct - All 5 versions
… Ng, J Yu, A van Hasselt, Y Cao, YX Zeng, AHY Wong, X … - Oncogene, 2008 - nature.com 16q24 is frequently deleted in multiple tumors including cancers of nasopharynx, esophagus, breast, prostate and liver. By array comparative genomic hybridization (aCGH), we refined a 16q24 hemizygous deletion in nasopharyngeal carcinoma (NPC) cell lines. ... Cited by 11 - Related articles - All 7 versions
biomedcentral.com[PDF]… , QS Feng, LZ Chen, DX Lin, YX Zeng - Journal of …, 2004 - biomedcentral.com ... 5. Zong YS, Sham JS, Ng MH, Ou XT, Guo YQ, Zheng SA, Liang JS, Qiu H: Immunoglobulin A against viral capsid antigen of Epstein- Barr virus and indirect mirror examination of the nasophar- ynx in the detection of asymptomatic nasopharyngealcarcinoma. ... Cited by 8 - Related articles - View as HTML - All 16 versions
JY Shao, WF Zeng, YX Zeng - … Aizheng= Chinese journal of cancer, 2002 - ncbi.nlm.nih.gov The aim of this paper was to discuss the molecular genetic events in the development and progression of nasopharyngeal carcinoma (NPC), and the correlation between genetic alterations and clinicopathological changes of NPC. Analyzed by LOH (loss of heterozygosity) and CGH (comparative ... Cited by 6 - Related articles
… , WJ Xia, HF Kung, XY Guan, YX Zeng - American journal of …, 2008 - ajcp.ascpjournals.org AIB1, a candidate oncogene in breast cancer, is commonly amplified and overexpressed in several types of human cancers. In this study, expression and amplification of AIB1 in nasopharyngeal carcinoma (NPC) were studied by immunohistochemical analysis and fluorescence in situ ... Cited by 6 - Related articles - BL Direct - All 4 versions
sgmjournals.org[HTML]… , QS Feng, Q Liu, CN Qian, YX Zeng - Journal of General …, 2008 - Soc General Microbiol Immunoglobulin (Ig) A and/or IgG reactivities to several Epstein–Barr virus (EBV) antigens have been used to facilitate diagnosis of nasopharyngeal carcinoma (NPC). However, antibodies against gp78, an EBV membrane glycoprotein, have not been examined to this day. In ... Cited by 6 - Related articles - BL Direct - All 5 versions
[CITATION] Serological mass survey of nasopharyngeal carcinoma
Y Zeng, YX Liu, JN Wei, JS Zhu, SL Cai, PZ Wang, JM … - Acta Acad Med Sin, 1979 Cited by 11 - Related articles
KW Lo, DP Huang - Seminars in cancer biology, 2002 - Elsevier ... Cited By in Scopus (68). Permissions & Reprints. Genetic and epigenetic changes in nasopharyngealcarcinoma. ... Available online 19 November 2002. Abstract. Nasopharyngeal carcinoma (NPC) is a malignancy with remarkable racial and geographic distribution. ... Cited by 100 - Related articles - BL Direct - All 6 versions
… Song, LZ Chen, RH Zhang, XJ Yu, YX Zeng - Cancer biology & therapy, 2006 - cat.inist.fr Signaling pathways activated by the Toll-like receptor 4 (TLR4) involve the induction of anti-cancer immunity. While screening for nasopharyngeal carcinoma (NPC) susceptibility genes, we isolated TLR4 and found that the 3'-untranslated region (3'-UTR) of exon 4 contained two ... Cited by 5 - Related articles - BL Direct - All 5 versions
… , A Poirier, H Ohshima, C Malaveille, Y Zeng… - …, 1988 - Oxford Univ Press ... Virology, 121, 184-194. 12. Zeng.Y., Liu.YX, Liu,ZR, Zhen.SW, Wei,JN, Zhu,JS and Zei,HS (1980) Application of an immunoenzymatic method and immunoautoradio- graphic method for a mass survey of nasopharyngealcarcinoma. Intervirology, 13, 162-168. 13. ... Cited by 23 - Related articles - All 5 versions
… HY Gao, HQ Mai, Y Zhang, X Guo, YX Zeng - Cancer Biol …, 2004 - landesbioscience.com Mitochondrial DNA (mtDNA) has a high mutation rate due at least in part to a lack of protective histones and an inefficient DNA repair system. The most frequently change in mtDNA is the so-called Common Deletion (CD), which accumulates in patients with hetero-plasmic ... Cited by 5 - Related articles - Cached - All 5 versions
… , JY Shao, XM Liang, YF Xia, YX Zeng - Cancer biology & …, 2008 - ncbi.nlm.nih.gov Nasopharyngeal carcinoma (NPC) is one of the most common cancers in southern China, and is highly sensitive to radiotherapy. The control region (D-loop) of mtDNA is a polymorphic region in which point mutations occur frequently. In this study, point mutation and common ... Cited by 5 - Related articles - All 4 versions
… MY Huang, CW Kou, XF Zhu, YX Zeng … - … Journal of Cancer, 2009 - interscience.wiley.com Expression of caveolin-1 (Cav-1) and extracellular matrix metallo- proteinase inducer (EMMPRIN/CD147) and their prognostic sig- nificance were analyzed in archive NPC samples. Cav-1 and CD147 were overexpressed in 49.48% (96/194) and 59.39% (117/ ... Cited by 6 - Related articles - All 3 versions
HD Zhou, GY Li, YX Yang, XL Li, SR Sheng, WL … - Molecular …, 2006 - Elsevier ... Cited By in Scopus (19). Permissions & Reprints. Intracellular co-localization of SPLUNC1 protein with nanobacteria in nasopharyngealcarcinoma epithelia HNE1 cells depended on the bactericidal permeability increasing protein domain. ... Cited by 29 - Related articles - All 3 versions
aacrjournals.org[HTML]CN Qian, X Guo, B Cao, EJ Kort, CC Lee, J Chen, LM … - Cancer research, 2002 - AACR ... (Austin, TX, catalogue no. ... 2 The abbreviations used are: NPC, nasopharyngealcarcinoma; SO, styloid process-occipital foramen; HGF/SF, hepatocyte growth factor/scatter factor; VEGF, vascular endothelial growth factor; TTBS, Tween 20 in Tris buffered saline; CI, confidence ... Cited by 84 - Related articles - BL Direct - All 4 versions
… , PH Wu, L Zheng, CM Ruan, L Li, YX Mo, … - … journal of cancer, 2003 - ncbi.nlm.nih.gov ... [Spiral computed tomography (CT) and magnetic resonance imaging (MRI) in assessment of the skull base encroachment in nasopharyngealcarcinoma] [Article in Chinese] Xie CM, Liang BL, Wu PH, Zheng L, Ruan CM, Li L, Mo YX, Zhong R, Chen YX, Lin HG. ... Cited by 7 - Related articles
… Jia, HD Qin, H Liang, ZG Pan, YX Zeng - … journal of cancer, 2004 - ncbi.nlm.nih.gov BACKGROUND & OBJECTIVE: The etiology of nasopharyngeal carcinoma (NPC) is associated with environmental and hereditary factors. Xenobiotics from environment must be activated to derive carcinogens. Several cytochrome P450 (CYP450) metabolic enzymes participate ... Cited by 4 - Related articles
J Zeng, CH Gong, MG Jan, Z Fun, … - … Journal of Cancer, 1983 - interscience.wiley.com ... J. Cancer, 29, 139-141 (19826). ZENG, Y., LIU, YX, LIU, ZR, CHEN, SW, WEI, JN, ZHU, JS, and ZAI, HJ, Application of an immunoenzymatic method and an immunoautoradiographic method for a mass survey of nasopharyngealcarcinoma. Infervirology, 13, 162-168 (1982~). Cited by 19 - Related articles - All 3 versions