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呼吸病学家Peter Barnes的学术成就
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科研生涯与学术成就：
Peter Barnes
Department of Thoracic Medicine, Imperial College School of Medicine, UK
http://f1000medicine.com/member/1657146821606700
http://www1.imperial.ac.uk/medicine/people/p.j.barnes/
主要论著与被引用情况：
endo.gr [HTML]PJ Barnes, M Karin - The New England journal of medicine, 1997 - endo.gr
What causes these diseases is still a mystery, but the disease process results from an interplay
of genetic and environmental factors. Genes, such as those for atopy in asthma and for HLA antigens
in rheumatoid arthritis and inflammatory bowel disease, may determine a patient's ...
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What causes these diseases is still a mystery, but the disease process results from an interplay
of genetic and environmental factors. Genes, such as those for atopy in asthma and for HLA antigens
in rheumatoid arthritis and inflammatory bowel disease, may determine a patient's ...
Cited by 2851 - Related articles - Cached - BL Direct - All 7 versions
portlandpress.com [PDF]PJ Barnes, I Adcock, M Spedding, PM … - Trends in pharmacological …, 1993 - Elsevier
Glucocorticosteroids are highly effective in controlling inflammation and the molecular mechanisms
involved are now becoming clear. Activation of glucocorticoid receptors results in increased or
decreased transcription of a number of genes involved in the inflammatory process. Of ...
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Glucocorticosteroids are highly effective in controlling inflammation and the molecular mechanisms
involved are now becoming clear. Activation of glucocorticoid receptors results in increased or
decreased transcription of a number of genes involved in the inflammatory process. Of ...
Cited by 1164 - Related articles - BL Direct - All 17 versions
nejm.org [HTML]… , AE Tattersfield, P O'Byrne, PJ Barnes, A … - … England Journal of …, 1997 - content.nejm.org
Methods After a four-week run-in period of treatment with budesonide (800 µg twice daily), 852
patients being treated with glucocorticoids were randomly assigned to one of four treatments
given twice daily by means of a dry-powder inhaler (Turbuhaler): 100 µg of budesonide ...
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Methods After a four-week run-in period of treatment with budesonide (800 µg twice daily), 852
patients being treated with glucocorticoids were randomly assigned to one of four treatments
given twice daily by means of a dry-powder inhaler (Turbuhaler): 100 µg of budesonide ...
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… , TT Hansel, ST Holgate, PJ Sterk, PJ Barnes - The Lancet, 2000 - Elsevier
Monoclonal antibody against IL-5 lowered the mean blood eosinophil count at day 29 from
0·25x10 9 /L (95% CI 0·16-0·34) in the placebo group to 0·04x10 9 /L (0·00-0·07) in the 10
mg/kg group (p<0·0001), and prevented the blood eosinophilia that follows allergen ...
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Monoclonal antibody against IL-5 lowered the mean blood eosinophil count at day 29 from
0·25x10 9 /L (95% CI 0·16-0·34) in the placebo group to 0·04x10 9 /L (0·00-0·07) in the 10
mg/kg group (p<0·0001), and prevented the blood eosinophilia that follows allergen ...
Cited by 947 - Related articles - BL Direct - All 9 versions
171.66.122.149 [HTML]… S Hurd, A Anzueto, PJ Barnes, SA Buist, P … - American journal of …, 2007 - 171.66.122.149
Chronic obstructive pulmonary disease (COPD) remains a major public health problem. It is the
fourth leading cause of chronic morbidity and mortality in the United States, and is projected
to rank fifth in 2020 in burden of disease worldwide, according to a study published by the ...
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Chronic obstructive pulmonary disease (COPD) remains a major public health problem. It is the
fourth leading cause of chronic morbidity and mortality in the United States, and is projected
to rank fifth in 2020 in burden of disease worldwide, according to a study published by the ...
Cited by 917 - Related articles - BL Direct - All 26 versions
aspetjournals.org [HTML]PJ Barnes, KF Chung, CP Page - Pharmacological reviews, 1998 - ASPET
Asthma is a complex chronic inflammatory disease of the airways that involves the activation
of many inflammatory and structural cells, all of which release inflammatory mediators that result
in the typical pathophysiological changes of asthma (Barnes, 1996a) (table1). By ...
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Asthma is a complex chronic inflammatory disease of the airways that involves the activation
of many inflammatory and structural cells, all of which release inflammatory mediators that result
in the typical pathophysiological changes of asthma (Barnes, 1996a) (table1). By ...
Cited by 791 - Related articles - BL Direct - All 10 versions
atsjournals.org [HTML]PJ BARNES, S PEDERSEN, WW … - American journal of …, 1998 - Am Thoracic Soc
Inhaled corticosteroids have revolutionized the treatment of asthma and have now become the
mainstay of therapy for patients with chronic disease (1). In a supplement to this journal published
5 yr ago the currently available data on efficacy and safety of inhaled corticosteroids was ...
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Inhaled corticosteroids have revolutionized the treatment of asthma and have now become the
mainstay of therapy for patients with chronic disease (1). In a supplement to this journal published
5 yr ago the currently available data on efficacy and safety of inhaled corticosteroids was ...
Cited by 565 - Related articles - All 7 versions
nejm.org [HTML]PJ Barnes - New England Journal of Medicine, 1995 - content.nejm.org
Glucocorticoids may have direct inhibitory effects on many of the cells involved in airway inflammation
in asthma, including macrophages, T-lymphocytes, eosinophils, and airway epithelial cells. 3
In culture, the drugs decrease cytokine-mediated survival of eosinophils by stimulating ...
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Glucocorticoids may have direct inhibitory effects on many of the cells involved in airway inflammation
in asthma, including macrophages, T-lymphocytes, eosinophils, and airway epithelial cells. 3
In culture, the drugs decrease cytokine-mediated survival of eosinophils by stimulating ...
Cited by 536 - Related articles - BL Direct - All 5 versions
atsjournals.org [HTML]SA Kharitonov, PJ Barnes - … journal of respiratory and critical care …, 2001 - Am Thoracic Soc
There has recently been an explosion of interest in the analysis of breath constituents as a way
of monitoring inflammation and oxidative stress in the lungs. Here we review the use of exhaled
breath analysis in the diagnosis and monitoring of lung disease. Although most studies ...
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There has recently been an explosion of interest in the analysis of breath constituents as a way
of monitoring inflammation and oxidative stress in the lungs. Here we review the use of exhaled
breath analysis in the diagnosis and monitoring of lung disease. Although most studies ...
Cited by 527 - Related articles - BL Direct - All 6 versions
atsjournals.org [HTML]… O'BYRNE, PJ Barnes, R Rodriguez-Roisin … - American journal of …, 2001 - Am Thoracic Soc
The optimal treatment for mild asthma is uncertain. We assessed the effects of adding a
long-acting inhaled beta-agonist, formoterol, to low doses of an inhaled corticosteroid,
budesonide, for 1 yr in subjects with mild asthma, receiving no or only a small dose of ...
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The optimal treatment for mild asthma is uncertain. We assessed the effects of adding a
long-acting inhaled beta-agonist, formoterol, to low doses of an inhaled corticosteroid,
budesonide, for 1 yr in subjects with mild asthma, receiving no or only a small dose of ...
Cited by 474 - Related articles - BL Direct - All 9 versions
… , A Jatakanon, YM Worsdell, PJ Barnes - American journal of …, 1997 - Am Thoracic Soc
The role of glucocorticoids in the treatment of chronic obstructive pulmonary disease (COPD)
is controversial. We have previously described high numbers of neutrophils and high concentrations
of the inflammatory cytokines interleukin-8 (IL-8) and tumor necrosis factor-alpha (TNF- ...
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The role of glucocorticoids in the treatment of chronic obstructive pulmonary disease (COPD)
is controversial. We have previously described high numbers of neutrophils and high concentrations
of the inflammatory cytokines interleukin-8 (IL-8) and tumor necrosis factor-alpha (TNF- ...
Cited by 436 - Related articles - BL Direct - All 4 versions
PJ Barnes, FY Liew - Immunology today, 1995 - Elsevier
Asthmatic patients show an increased expression of inducible nitric oxide synthase (iNOS) in
airway epithelial cells and an increased level of nitric oxide (NO) in exhaled air. The NO derived
from airway epithelial cells may be a mechanism for amplifying and perpetuating ...
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Asthmatic patients show an increased expression of inducible nitric oxide synthase (iNOS) in
airway epithelial cells and an increased level of nitric oxide (NO) in exhaled air. The NO derived
from airway epithelial cells may be a mechanism for amplifying and perpetuating ...
Cited by 393 - Related articles - BL Direct - All 5 versions
171.66.122.149 [HTML]… Maziak, SAM Lim, KF Chung, PJ Barnes - American journal of …, 1999 - 171.66.122.149
Airway inflammation in severe asthma is not well characterized but may involve neutrophils.
We have compared induced sputum profiles in patients with asthma of varying severity and normal
control subjects. We have also measured exhaled nitric oxide (NO) as a noninvasive ...
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Airway inflammation in severe asthma is not well characterized but may involve neutrophils.
We have compared induced sputum profiles in patients with asthma of varying severity and normal
control subjects. We have also measured exhaled nitric oxide (NO) as a noninvasive ...
Cited by 442 - Related articles - BL Direct - All 4 versions
… , M Engele, PA Sieling, PF Barnes, M Rollinghoff, PL … - Science, 2001 - sciencemag.org
This copy is for your personal, non-commercial use only. ... . clicking here colleagues,
clients, or customers by ... , you can order high-quality copies for your ... If you wish to distribute
this article to others ... Permission to republish or repurpose articles or portions of articles
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This copy is for your personal, non-commercial use only. ... . clicking here colleagues,
clients, or customers by ... , you can order high-quality copies for your ... If you wish to distribute
this article to others ... Permission to republish or repurpose articles or portions of articles
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PJ Barnes - Journal of allergy and clinical immunology, 1989 - Elsevier
Recent studies have suggested that inflammation may play an important role in the characteristic
bronchial hyperresponsiveness and symptoms of chronic asthma. The mechanisms by which
inflammatory cells, mediators, and nerves interact to produce the features of asthma are ...
Cited by 367 - Related articles - All 5 versions
Recent studies have suggested that inflammation may play an important role in the characteristic
bronchial hyperresponsiveness and symptoms of chronic asthma. The mechanisms by which
inflammatory cells, mediators, and nerves interact to produce the features of asthma are ...
Cited by 367 - Related articles - All 5 versions
nejm.org [HTML]DV Havlir, PF Barnes - New England Journal of Medicine, 1999 - content.nejm.org
Tuberculosis remains an important problem in patients with human immunodeficiency virus
(HIV) infection in the United States, with an estimated 6000 to 9000 new cases annually. 1 The
case rates are extraordinarily high among indigent patients and substance abusers, and ...
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Tuberculosis remains an important problem in patients with human immunodeficiency virus
(HIV) infection in the United States, with an estimated 6000 to 9000 new cases annually. 1 The
case rates are extraordinarily high among indigent patients and substance abusers, and ...
Cited by 348 - Related articles - BL Direct - All 9 versions
… , K Uyemura, S Cho, PF Barnes, JP Rosat, A Sette, MB … - Science, 1997 - sciencemag.org
This copy is for your personal, non-commercial use only. ... . clicking here colleagues,
clients, or customers by ... , you can order high-quality copies for your ... If you wish to distribute
this article to others ... Permission to republish or repurpose articles or portions of articles
Cited by 367 - Related articles - BL Direct - All 10 versions
This copy is for your personal, non-commercial use only. ... . clicking here colleagues,
clients, or customers by ... , you can order high-quality copies for your ... If you wish to distribute
this article to others ... Permission to republish or repurpose articles or portions of articles
Cited by 367 - Related articles - BL Direct - All 10 versions
atsjournals.org [HTML]… , SA KHARITONOV, PJ BARNES - American journal of …, 2000 - Am Thoracic Soc
Most of the studies linking chronic obstructive pulmonary disease (COPD) with oxidative stress
are in vitro, using invasive techniques, or measuring systemic oxidative stress. The aim of this
study was to quantify oxidative stress in the lungs in patients with COPD and in healthy ...
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Most of the studies linking chronic obstructive pulmonary disease (COPD) with oxidative stress
are in vitro, using invasive techniques, or measuring systemic oxidative stress. The aim of this
study was to quantify oxidative stress in the lungs in patients with COPD and in healthy ...
Cited by 331 - Related articles - BL Direct - All 4 versions
PJ Barnes - Free Radical Biology and Medicine, 1990 - Elsevier
Reactive oxygen species may be generated by several inflammatory cells which participate in
airway inflammation and their production may be increased in asthma. Oxygen metabolites may
contribute to the epithelial damage which is characteristic of asthmatic airways and may ...
Cited by 333 - Related articles - All 3 versions
Reactive oxygen species may be generated by several inflammatory cells which participate in
airway inflammation and their production may be increased in asthma. Oxygen metabolites may
contribute to the epithelial damage which is characteristic of asthmatic airways and may ...
Cited by 333 - Related articles - All 3 versions
… , JA Bock, MJ Boyce, TT Hansel, ST Holgate, PJ Barnes - The Lancet, 2000 - Elsevier
IL-12 caused a significant decrease from baseline in the main peripheral blood eosinophil count
24 h after the fourth injection compared with placebo (p=0·0001). Sputum eosinophils were also
significantly decreased 24 h after allergen challenge when treated with IL-12 compared ...
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IL-12 caused a significant decrease from baseline in the main peripheral blood eosinophil count
24 h after the fourth injection compared with placebo (p=0·0001). Sputum eosinophils were also
significantly decreased 24 h after allergen challenge when treated with IL-12 compared ...
Cited by 322 - Related articles - BL Direct - All 8 versions
K Ito, PJ Barnes, IM Adcock - Molecular and Cellular Biology, 2000 - Am Soc Microbiol
We have investigated the ability of dexamethasone to regulate interleukin-1 (IL-1 )-induced gene
expression, histone acetyltransferase (HAT) and histone deacetylase (HDAC) activity. Low concentrations
of dexamethasone (10 10 M) repress IL-1 -stimulated granulocyte-macrophage colony- ...
Cited by 345 - Related articles - BL Direct - All 6 versions
171.66.122.149 [HTML]… , J Nightingale, SA Kharitonov, PJ Barnes - American journal of …, 1999 - 171.66.122.149
Oxidative stress has an important role in the pathogenesis of asthma. 8-Isoprostane is a prostaglandin
(PG)-F 2 -like compound belonging to the F 2 isoprostane class that is produced in vivo by the
free radical-catalyzed peroxidation of arachidonic acid. 8-Isoprostane is a biomarker of ...
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Oxidative stress has an important role in the pathogenesis of asthma. 8-Isoprostane is a prostaglandin
(PG)-F 2 -like compound belonging to the F 2 isoprostane class that is produced in vivo by the
free radical-catalyzed peroxidation of arachidonic acid. 8-Isoprostane is a biomarker of ...
Cited by 307 - Related articles - BL Direct - All 5 versions
… Kuitert, M Bergmann, IM Adcock, PJ Barnes - Biochemical and …, 1997 - Elsevier
The cyclooxygenase (COX) isoforms COX-1 and COX-2 convert arachidonic acid to prostaglandin
(PG) precursors and are a limiting step in PG production. Interleukin-1β (IL-1β) treatment of type
II A549 cells increases PGE 2 synthesis via transcription- and translation-dependent ...
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The cyclooxygenase (COX) isoforms COX-1 and COX-2 convert arachidonic acid to prostaglandin
(PG) precursors and are a limiting step in PG production. Interleukin-1β (IL-1β) treatment of type
II A549 cells increases PGE 2 synthesis via transcription- and translation-dependent ...
Cited by 276 - Related articles - BL Direct - All 6 versions
… Belvisi, C David Stretton, M Yacoub, PJ Barnes - European journal of …, 1992 - Elsevier
European Journal of Pharmacology, 210 (1992) 221-222 C 1992 Elsevier Science Publishers
BV All rights reserved 0014-2999/92/$05.00 EJP 03328 Rapid communication Nitric oxide is
the endogenous neurotransmitter of bronchodilator nerves in humans Maria G. Belvisi, C. ...
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European Journal of Pharmacology, 210 (1992) 221-222 C 1992 Elsevier Science Publishers
BV All rights reserved 0014-2999/92/$05.00 EJP 03328 Rapid communication Nitric oxide is
the endogenous neurotransmitter of bronchodilator nerves in humans Maria G. Belvisi, C. ...
Cited by 262 - Related articles - All 4 versions
bmj.com [PDF]PJ Barnes, MG Belvisi - Thorax, 1993 - thorax.bmj.com
Even five years ago few could have realised that the simple gas nitric oxide (NO) would be involved
in the regulation of so many physiological functions and pathophysiologi- cal processes. There
has been an explosion of information about nitric oxide which appears to be involved in ...
Cited by 311 - Related articles - BL Direct - All 8 versions
Even five years ago few could have realised that the simple gas nitric oxide (NO) would be involved
in the regulation of so many physiological functions and pathophysiologi- cal processes. There
has been an explosion of information about nitric oxide which appears to be involved in ...
Cited by 311 - Related articles - BL Direct - All 8 versions
nejm.org [PDF]… Hayashi, IM Adcock, JC Hogg, PJ Barnes - … England Journal of …, 2005 - content.nejm.org
From the Airway Disease Section, National Heart and Lung Institute, Imperial College, London
(KI, MI, BC, OMK, IMA, PJB); the Chest and Allergy Clinic, St. Mary's Hospital, London
(OMK); Uni- versity of British Columbia and the James Hogg iCAPTURE Center for ...
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From the Airway Disease Section, National Heart and Lung Institute, Imperial College, London
(KI, MI, BC, OMK, IMA, PJB); the Chest and Allergy Clinic, St. Mary's Hospital, London
(OMK); Uni- versity of British Columbia and the James Hogg iCAPTURE Center for ...
Cited by 332 - Related articles - All 11 versions
fasebj.org [HTML]D Saleh, P Ernst, S Lim, PJ Barnes, A Giaid - The FASEB Journal, 1998 - FASEB
THE AIRWAY EPITHELIUM is exposed to various exogenous and endogenous oxidants that
influence its function and structure (1). Endogenous oxidants are produced by the reaction of
local free radicals and intracellular reactive oxygen species, and often lead to extensive ...
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THE AIRWAY EPITHELIUM is exposed to various exogenous and endogenous oxidants that
influence its function and structure (1). Endogenous oxidants are produced by the reaction of
local free radicals and intracellular reactive oxygen species, and often lead to extensive ...
Cited by 303 - Related articles - BL Direct - All 5 versions
VM Keatings, PJ Barnes - … journal of respiratory and critical care …, 1997 - 171.66.122.149
Airway inflammation is present in asthma and is thought to play a significant part in the development
of airflow obstruction. In chronic obstructive pulmonary disease (COPD), neutrophilic inflammation
is present in the airway lumen, whereas the submucosa displays a lymphocytic infiltrate. ...
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Airway inflammation is present in asthma and is thought to play a significant part in the development
of airflow obstruction. In chronic obstructive pulmonary disease (COPD), neutrophilic inflammation
is present in the airway lumen, whereas the submucosa displays a lymphocytic infiltrate. ...
Cited by 279 - Related articles - BL Direct - All 4 versions
atsjournals.org [HTML]… , JL MATTHEWS, PJ BARNES - American journal of …, 1999 - Am Thoracic Soc
Inhaled corticosteroids are widely prescribed for the treatment of stable chronic obstructive pulmonary
disease (COPD), despite lack of proven efficacy. Because COPD involves airway inflammation
and probable protease-antiprotease imbalance, we examined the effect of high dose ...
Cited by 292 - Related articles - BL Direct - All 4 versions
Inhaled corticosteroids are widely prescribed for the treatment of stable chronic obstructive pulmonary
disease (COPD), despite lack of proven efficacy. Because COPD involves airway inflammation
and probable protease-antiprotease imbalance, we examined the effect of high dose ...
Cited by 292 - Related articles - BL Direct - All 4 versions
nih.gov [PDF]PC Barnes - BMJ: British Medical Journal, 1995 - ncbi.nlm.nih.gov
Symmetrical small joint polyarthritis, with or without large joints also being affected, is the commonest
presentation. In elderly patients the start of rheumatoid arthritis may be indistinguishable from
polymyalgia rheumatica. Occasionally, rheumatoid arthritis may present as a ...
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Symmetrical small joint polyarthritis, with or without large joints also being affected, is the commonest
presentation. In elderly patients the start of rheumatoid arthritis may be indistinguishable from
polymyalgia rheumatica. Occasionally, rheumatoid arthritis may present as a ...
Cited by 250 - Related articles - All 11 versions
… , BJ O'Connor, DJ Evans, PJ Barnes - American journal of …, 1995 - Am Thoracic Soc
The concentration of nitric oxide (NO) is increased in the exhaled air of asthmatic patients and
may reflect cytokine-mediated inflammation in the airways. We investigated whether
allergen-induced inflammation causes an elevation in the level of exhaled NO. Of 25 ...
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The concentration of nitric oxide (NO) is increased in the exhaled air of asthmatic patients and
may reflect cytokine-mediated inflammation in the airways. We investigated whether
allergen-induced inflammation causes an elevation in the level of exhaled NO. Of 25 ...
Cited by 260 - Related articles - BL Direct - All 4 versions
… Robbins, D Yates, V Keatings, PJ Barnes - American journal of …, 1995 - 171.66.122.149
Cigarette smoking is associated with an increased risk of respiratory tract infections, chronic
airway disease, and cardiovascular diseases, all of which may be modulated by endogenous
nitric oxide (NO). We have investigated whether cigarette smoking reduces the production ...
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Cigarette smoking is associated with an increased risk of respiratory tract infections, chronic
airway disease, and cardiovascular diseases, all of which may be modulated by endogenous
nitric oxide (NO). We have investigated whether cigarette smoking reduces the production ...
Cited by 259 - Related articles - BL Direct - All 4 versions
nejm.org [HTML]… , KF Chung, BJ O'Connor, PJ Barnes - … England Journal of …, 1997 - content.nejm.org
Results Both treatments resulted in improvements in lung function that were sustained throughout
the study. As compared with treatment with high-dose budesonide, treatment with low-dose budesonide
plus theophylline resulted in greater improvements in forced vital capacity (P = 0.03) and ...
Cited by 259 - Related articles - BL Direct - All 10 versions
Results Both treatments resulted in improvements in lung function that were sustained throughout
the study. As compared with treatment with high-dose budesonide, treatment with low-dose budesonide
plus theophylline resulted in greater improvements in forced vital capacity (P = 0.03) and ...
Cited by 259 - Related articles - BL Direct - All 10 versions
atsjournals.org [HTML]… KRISHNAN, IANM ADCOCK, PJ BARNES … - American journal of …, 1998 - Am Thoracic Soc
Asthma is associated with increased expression of inflammatory proteins including
cytokines, enzymes, and adhesion molecules. Induction of many of the genes for these proteins
is regulated by the transcription factor, nuclear factor- B (NF- B). We therefore examined ...
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Asthma is associated with increased expression of inflammatory proteins including
cytokines, enzymes, and adhesion molecules. Induction of many of the genes for these proteins
is regulated by the transcription factor, nuclear factor- B (NF- B). We therefore examined ...
Cited by 263 - Related articles - BL Direct - All 4 versions
… Hansell, RB Logan-Sinclair, PJ Barnes - American journal of …, 1995 - 171.66.122.149
... SA Kharitonov, AU Wells, BJ O'Connor, PJ Cole, DM Hansell, RB Logan-Sinclair and PJ Barnes
Department of Thoracic Medicine, National Heart and Lung Institute, London, England. ... Home
page SA KHARITONOV and PJ BARNES Exhaled Markers of Pulmonary Disease Am. ...
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... SA Kharitonov, AU Wells, BJ O'Connor, PJ Cole, DM Hansell, RB Logan-Sinclair and PJ Barnes
Department of Thoracic Medicine, National Heart and Lung Institute, London, England. ... Home
page SA KHARITONOV and PJ BARNES Exhaled Markers of Pulmonary Disease Am. ...
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chestpubs.org [HTML]PJ Barnes - Chest, 2000 - chestjournal.chestpubs.org
Although considerable progress has been made in understanding the cellular and molecular
mechanisms of asthma, much less attention has been paid to COPD. The inflammatory process
in COPD is very different from that in asthma, with different inflammatory cells, mediators, ...
Cited by 249 - Related articles - BL Direct - All 6 versions
Although considerable progress has been made in understanding the cellular and molecular
mechanisms of asthma, much less attention has been paid to COPD. The inflammatory process
in COPD is very different from that in asthma, with different inflammatory cells, mediators, ...
Cited by 249 - Related articles - BL Direct - All 6 versions
171.66.122.149 [HTML]A Jatakanon, SAM Lim, PJ Barnes - American journal of …, 2000 - 171.66.122.149
Exacerbations of asthma are likely to be due to an increase in airway inflammation. We have
studied noninvasive markers of airway inflammation in asthma exacerbations induced by reducing
the dose of inhaled corticosteroids. Following a 2-wk run-in period, mild exacerbations ...
Cited by 244 - Related articles - BL Direct - All 5 versions
Exacerbations of asthma are likely to be due to an increase in airway inflammation. We have
studied noninvasive markers of airway inflammation in asthma exacerbations induced by reducing
the dose of inhaled corticosteroids. Following a 2-wk run-in period, mild exacerbations ...
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PF Barnes, D Chatterjee, JS Abrams, S … - The Journal of …, 1992 - Am Assoc Immnol
0022-1767/92/1492-0541$02.00/0 Copyright 0 1992 by The American Association of Immunologists
THE JOURNAL OF 1MMUNOLOGY ... Vol. 149, 541-547. No. 2. July 15. 1992 Printed in USA
... CYTOKINE PRODUCTION INDUCED BY Mycobacterium tuberculosis ...
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0022-1767/92/1492-0541$02.00/0 Copyright 0 1992 by The American Association of Immunologists
THE JOURNAL OF 1MMUNOLOGY ... Vol. 149, 541-547. No. 2. July 15. 1992 Printed in USA
... CYTOKINE PRODUCTION INDUCED BY Mycobacterium tuberculosis ...
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PJ Barnes, P Minette, J Maclagan - Trends in Pharmacological Sciences, 1988 - Elsevier
Subtypes of muscarinic receptor have recently been shown to exist in the airways of several
species, including humans. M 1 receptors may be present in sympathetic nerves and parasympathetic
ganglia. M 2 receptors on cholinergic nerves (autoreceptors) and M 3 receptors on ...
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Subtypes of muscarinic receptor have recently been shown to exist in the airways of several
species, including humans. M 1 receptors may be present in sympathetic nerves and parasympathetic
ganglia. M 2 receptors on cholinergic nerves (autoreceptors) and M 3 receptors on ...
Cited by 213 - Related articles - BL Direct - All 8 versions
nih.gov [PDF]… Lin, DV Iyer, J Gong, JS Abrams, PF Barnes - Infection and …, 1995 - Am Soc Microbiol
MING ZHANG,1 YUANGUANG LIN,1 DINAKAR V. IYER,1 JIANHUA GONG,1 JOHN S.
ABRAMS,2 AND PETER F. BARNES1* Division of Infectious Diseases, Department of
Medicine, University of Southern California School of Medicine, Los Angeles, California ...
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MING ZHANG,1 YUANGUANG LIN,1 DINAKAR V. IYER,1 JIANHUA GONG,1 JOHN S.
ABRAMS,2 AND PETER F. BARNES1* Division of Infectious Diseases, Department of
Medicine, University of Southern California School of Medicine, Los Angeles, California ...
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