Osanetant (SR142801) 是一种选择性的 NK3 受体拮抗剂 

https://blog.sciencenet.cn/blog-3536222-1444527.html

http://www.pubmedplus.cn/P/SearchQuickResult?wd=9619e4bc-975e-417c-b37e-b32e0937d016

• 1. Opinion: NK3 receptor antagonists: the next generation of antipsychotics?

  Will Spooren,Claus Riemer,Herbert Meltzer

  Will Spooren and Claus Riemer are at F. Hoffmann-La Roche, Pharmaceuticals Division, Psychiatry-Disease Area, Building 72-148, 4070 Basel, Switzerland. will.spooren@roche.com

  will.spooren@roche.com

  Nat Rev Drug Discov (P 1474-1776 E 1474-1776) H指数：289 2005 年 4 卷 12 期 967-75 页

  PMID：16341062 相似文献

  文摘 DOI链接 Nature Publishing Group

• 2. Activation of dopaminergic and cholinergic neurotransmission by tachykinin NK3 receptor stimulation: an in vivo microdialysis approach in guinea pig.

  N Marco,A Thirion,G Mons,I Bougault,G Le Fur,P Soubrié,R Steinberg

  Sanofi Recherche - Neuropsychiatry Department, Montpellier, France.

  Neuropeptides (P 0143-4179 E 0143-4179) H指数：63 1998 年 32 卷 5 期 481-8 页

  PMID：9845011 相似文献

https://pubmed.ncbi.nlm.nih.gov/16341062/

Review

 

Nat Rev Drug Discov

. 2005 Dec;4(12):967-75.

 doi: 10.1038/nrd1905.

Opinion: NK3 receptor antagonists: the next generation of antipsychotics?

Will Spooren 1, Claus Riemer, Herbert Meltzer

Affiliations expand

• PMID: 16341062

•  

• DOI: 10.1038/nrd1905

https://pubmed.ncbi.nlm.nih.gov/9845011/

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Neuropeptides

. 1998 Oct;32(5):481-8.

 doi: 10.1016/s0143-4179(98)90075-0.

Activation of dopaminergic and cholinergic neurotransmission by tachykinin NK3 receptor stimulation: an in vivo microdialysis approach in guinea pig

N Marco 1, A Thirion, G Mons, I Bougault, G Le Fur, P Soubrié, R Steinberg

Affiliations expand

• PMID: 9845011

•  

• DOI: 10.1016/s0143-4179(98)90075-0

http://www.pubmedplus.cn/P/SearchQuickResult?wd=c2441e4d-6dd7-4214-af77-30cd58a2fef1

• 主题词

• 记录数占%

01.	Antipsychotic Agents	52 篇	76.471%
02.	Humans	51 篇	75.000%
03.	Animals	41 篇	60.294%
04.	Schizophrenia	40 篇	58.824%
05.	Receptors, Neurokinin-3	35 篇	51.471%
06.	Piperidines	30 篇	44.118%
07.	Male	21 篇	30.882%
08.	Dose-Response Relationship, Drug	12 篇	17.647%
09.	Adult	9 篇	13.235%
10.	Peptide Fragments	9 篇	13.235%

http://www.pubmedplus.cn/P/SearchQuickResult?wd=46d6ea6a-d200-4bf9-a137-624a6470b1b4

• 主题词

• 记录数占%

01.	Animals	102 篇	99.029%
02.	Male	84 篇	81.553%
03.	Receptors, Neurokinin-3	72 篇	69.903%
04.	Peptide Fragments	71 篇	68.932%
05.	Substance P	71 篇	68.932%
06.	Rats	53 篇	51.456%
07.	Piperidines	44 篇	42.718%
08.	Guinea Pigs	43 篇	41.748%
09.	Dopamine	34 篇	33.010%
10.	In Vitro Techniques	34 篇	33.010%

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