博文
代谢功能障碍相关脂肪性肝病 研究主题分析
||
代谢功能障碍相关脂肪性肝病
1.MASLD早期阶段肝脏中一碳代谢发生变化；
2.脂肪肝中甘氨酸水平下降促进肝脏氧化应激，并提高肝脏对APAP毒性敏感；
3.肝细胞SHMT2催化甘氨酸合成丝氨酸，是脂肪肝中甘氨酸下降的主要原因；
4.通过饮食或遗传干预可提高肝脏中甘氨酸水平，并缓解APAP诱导的肝脏损伤。
https://blog.sciencenet.cn/blog-3483272-1419293.html
http://www.pubmedplus.cn/P/SearchQuickResult?wd=7f3e44af-60af-4181-8d98-391e3965ea53
| 01. | Humans | 142 篇 | 29.583% |
| 02. | Fatty Liver | 76 篇 | 15.833% |
| 03. | Non-alcoholic Fatty Liver Disease | 58 篇 | 12.083% |
| 04. | Metabolic Diseases | 44 篇 | 9.167% |
| 05. | Liver Cirrhosis | 37 篇 | 7.708% |
| 06. | Animals | 35 篇 | 7.292% |
| 07. | Liver | 28 篇 | 5.833% |
| 08. | Male | 27 篇 | 5.625% |
| 09. | Mice | 25 篇 | 5.208% |
| 10. | Obesity | 22 篇 | 4.583% |
http://www.pubmedplus.cn/P/SearchQuickResult?wd=167824ae-7849-4411-95df-24240bee89ef
| 01. | Non-alcoholic Fatty Liver Disease | 236 篇 | 100.000% |
| 02. | Obesity | 236 篇 | 100.000% |
| 03. | Humans | 180 篇 | 76.271% |
| 04. | Animals | 114 篇 | 48.305% |
| 05. | Male | 103 篇 | 43.644% |
| 06. | Liver | 102 篇 | 43.220% |
| 07. | Insulin Resistance | 81 篇 | 34.322% |
| 08. | Female | 57 篇 | 24.153% |
| 09. | Diet, High-Fat | 52 篇 | 22.034% |
| 10. | Mice | 48 篇 | 20.339% |
https://kns.cnki.net/kns8s/search?classid=WD0FTY92&kw=MASLD&korder=SU
(1)
(1)
(1)
(1)
(1)
(1)
(1)
(1)
(1)
(1)
(2)
(2)
(2)
(2)
(1)
(1)
(1)
(1)
(1)
(1)
https://fx.wanfangdata.com.cn/keytrends/detail?theme_name=MASLD
https://blog.sciencenet.cn/blog-280034-1424088.html
上一篇：肌细胞因子Irisin 研究主题分析
下一篇：高瘦素血症 研究主题分析
