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Irisin是一种肌细胞因子,由其前体Ⅲ型纤连蛋白域蛋白5(FNDC5)裂解而来,可调节脂肪组织中的葡萄糖和脂质代谢,并通过加速白色脂肪组织的棕色化来增加能量消耗。
Neuron: Irisin让你不再困在时间里1. Irisin促进NEP分泌,导致 3D-AD 模型中Aβ减少;
2. 整合素αV/β5是星形胶质细胞上的Irisin受体,可诱导 NEP 分泌;
3. Irisin通过下调 ERK-STAT3 信号介导 NEP 分泌。
https://blog.sciencenet.cn/blog-3483272-1417502.html
http://www.pubmedplus.cn/P/SearchQuickResult?wd=66e506ae-1c07-4ab4-97d5-d8347e34cde4
01. | Obesity | 245 篇 | 100.000% |
02. | Fibronectins | 197 篇 | 80.408% |
03. | Humans | 196 篇 | 80.000% |
04. | Male | 110 篇 | 44.898% |
05. | Female | 100 篇 | 40.816% |
06. | Animals | 91 篇 | 37.143% |
07. | Adult | 70 篇 | 28.571% |
08. | Insulin Resistance | 65 篇 | 26.531% |
09. | Middle Aged | 59 篇 | 24.082% |
10. | Muscle, Skeletal | 57 篇 | 23.265% |
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