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NEJM:体内CRISPR基因编辑疗法可有效治疗血管性水肿
https://www.ebiotrade.com/newsf/2024-2/20240202104435718.htm
http://www.pubmedplus.cn/P/SearchQuickResult?wd=43a49b7b-7f3c-46d8-bcc5-f3d20d73c82a
1. CRISPR-Cas9 In Vivo Gene Editing of KLKB1 for Hereditary Angioedema.
From Te Toka Tumai, Department of Immunology, Auckland City Hospital (H.J.L., K.L.), and the Department of Medicine, University of Auckland (H.J.L.) - both in Auckland, New Zealand; the Department of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam (R.S.P., L.M.F., D.M.C.); Cambridge University Hospitals, NHS Foundation Trust, Cambridge, United Kingdom (P.G.); and Intellia Therapeutics, Cambridge, MA (D.M., J.S.B., M.Y.S., A.G., Y.X., C.B., J.D.V., A.M.A., M.L.M., M.D.M., J.S., B.W.H., S.S., J.L., L.S.-L., E.D.C., D.L.).
N Engl J Med (P 1533-4406 E 0028-4793) 2024 年 390 卷 5 期 432-441 页
PMID:38294975 相似文献
2. Clinical Progress in Hepatic Targeting for Novel Prophylactic Therapies in Hereditary Angioedema.
Marc A Riedl,Laura Bordone,Alexey Revenko,Kenneth B Newman,Danny M Cohn
Division of Allergy and Immunology, University of California, San Diego, La Jolla, Calif. Electronic address: mriedl@health.ucsd.edu.
mriedl@health.ucsd.edu
J Allergy Clin Immunol Pract (P 2213-2201 E ) H指数:0 2023 年
PMID:38142864 相似文献
http://www.pubmedplus.cn/P/SearchQuickResult?wd=a985500b-a698-43f6-8307-b0189ed86991
01. | Humans | 97 篇 | 96.040% |
02. | Angioedemas, Hereditary | 93 篇 | 92.079% |
03. | Complement C1 Inhibitor Protein | 83 篇 | 82.178% |
04. | Female | 58 篇 | 57.426% |
05. | Treatment Outcome | 57 篇 | 56.436% |
06. | Male | 53 篇 | 52.475% |
07. | Adult | 46 篇 | 45.545% |
08. | Middle Aged | 37 篇 | 36.634% |
09. | Adolescent | 32 篇 | 31.683% |
10. | Child | 29 篇 | 28.713% |
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