免疫补体介导阿尔兹海默病中突触丢失的新理论

https://www.ebiotrade.com/newsf/2024-1/20240113064532069.htm

检索到相关研究文献2篇 如下

https://pubmed.ncbi.nlm.nih.gov/37442133/

Immunity

. 2023 Aug 8;56(8):1794-1808.e8.

 doi: 10.1016/j.immuni.2023.06.016. Epub 2023 Jul 12.

TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration

Li Zhong 1, Xuan Sheng 2, Wanbing Wang 2, Yanzhong Li 2, Rengong Zhuo 3, Kai Wang 2, Lianshuai Zhang 2, Dan-Dan Hu 2, Yujuan Hong 2, Linting Chen 2, Hengjun Rao 2, Tingting Li 2, Muyang Chen 2, Zhihao Lin 2, Yun-Wu Zhang 2, Xin Wang 4, Xiao-Xin Yan 5, Xiaochun Chen 6, Guojun Bu 7, Xiao-Fen Chen 8

Affiliations expand

• PMID: 37442133

•  

• DOI: 10.1016/j.immuni.2023.06.016

https://pubmed.ncbi.nlm.nih.gov/35794654/

Acta Neuropathol Commun

. 2022 Jul 6;10(1):99.

 doi: 10.1186/s40478-022-01404-w.

Terminal complement pathway activation drives synaptic loss in Alzheimer's disease models

Sarah M Carpanini # 1, Megan Torvell # 1, Ryan J Bevan 1, Robert A J Byrne 1, Nikoleta Daskoulidou 1, Takashi Saito 2, Takaomi C Saido 3, Philip R Taylor 1, Timothy R Hughes 1, Wioleta M Zelek 1, B Paul Morgan 4

Affiliations expand

• PMID: 35794654

•  

• PMCID: PMC9258209

•  

• DOI: 10.1186/s40478-022-01404-w

Free PMC article

检索策略   高级检索  

((阿尔兹海默病[All Fields]) AND 免疫补体介导[All Fields]) AND 突触丢失[All Fields]

http://www.pubmedplus.cn/P/SearchQuickResult?wd=63df1759-0971-4a95-9bf8-1e96261ab839

• 1. TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration.

  Li Zhong,Xuan Sheng,Wanbing Wang,Yanzhong Li,Rengong Zhuo,Kai Wang,Lianshuai Zhang,Dan-Dan Hu,Yujuan Hong,Linting Chen,Hengjun Rao,Tingting Li,Muyang Chen,Zhihao Lin,Yun-Wu Zhang,Xin Wang,Xiao-Xin Yan,Xiaochun Chen,Guojun Bu,Xiao-Fen Chen

  Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen 361102, Fujian, China. Electronic address: zhongli@xmu.edu.cn.

  zhongli@xmu.edu.cn

  Immunity (P 1097-4180 E 1074-7613) H指数：355 2023 年 56 卷 8 期 1794-1808.e8 页

  PMID：37442133 相似文献

  文摘 DOI链接 Elsevier ScienceOvid Technologies, Inc.

• 2. Terminal complement pathway activation drives synaptic loss in Alzheimer's disease models.

  Sarah M Carpanini,Megan Torvell,Ryan J Bevan,Robert A J Byrne,Nikoleta Daskoulidou,Takashi Saito,Takaomi C Saido,Philip R Taylor,Timothy R Hughes,Wioleta M Zelek,B Paul Morgan

  UK Dementia Research Institute Cardiff, and Systems Immunity Research Institute, School of Medicine, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK.

  Morganbp@Cardiff.ac.uk

  Acta Neuropathol Commun (P 2051-5960 E 2051-5960) H指数：37 2022 年 10 卷 1 期 99 页

  PMID：35794654 相似文献

  文摘 DOI链接 BioMed CentralPubMed Central

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