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2023年1月12日,我院天然药物及仿生药物国家重点实验室马明研究团队在ACS Catalysis上发表了题为“Structural Insight into a Metal-Dependent Mutase Revealing an Arginine Residue-Covalently Mediated Interconversion between Nucleotide-Based Pyranose and Furanose”的研究论文。该研究阐明了呋喃糖环生物合成中第一个离子依赖型变位酶(mutase)的晶体结构,并揭示了一种精氨酸共价结合底物介导的吡喃糖环和呋喃糖环的相互转化机制。https://www.ebiotrade.com/newsf/2023-1/20230114065035080.htm
http://www.pubmedplus.cn/P/SearchQuickResult?wd=24c210b7-5a6c-4825-833e-3b3f399fa9fe
01. | Intramolecular Transferases | 16 篇 | 80.000% |
02. | Galactose | 6 篇 | 30.000% |
03. | Molecular Sequence Data | 5 篇 | 25.000% |
04. | Uridine Diphosphate | 5 篇 | 25.000% |
05. | Bacterial Proteins | 4 篇 | 20.000% |
06. | Cell Wall | 4 篇 | 20.000% |
07. | Recombinant Proteins | 4 篇 | 20.000% |
08. | Substrate Specificity | 4 篇 | 20.000% |
09. | Uridine Diphosphate Sugars | 4 篇 | 20.000% |
10. | Binding Sites | 3 篇 | 15.000% |
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