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诺奖发现 乳腺癌 BRCA1基因突变

已有 783 次阅读 2022-9-25 14:55 |个人分类:诺贝尔奖|系统分类:论文交流



Mary-Claire King,美国华盛顿大学医学和基因组科学教授

获奖原因:证明了乳腺癌和卵巢癌的遗传易感性,并发现了BRCA1基因突变所造成的影响。

https://news.sciencenet.cn/htmlnews/2022/9/486641.shtm

乳腺癌文献分析

http://www.pubmedplus.cn/P/SearchQuickResult?wd=9e83c3d7-24ce-424e-aaf8-6f9ce532e543


01.20221 篇4.167%
02.20211 篇4.167%
03.20201 篇4.167%
04.20191 篇4.167%
05.20181 篇4.167%
06.20163 篇12.500%
07.20152 篇8.333%
08.20141 篇4.167%
09.20131 篇4.167%
10.20121 篇4.167%
11.20092 篇8.333%
12.20071 篇4.167%
13.20064 篇16.667%
14.20041 篇4.167%
15.20031 篇4.167%
16.20001 篇4.167%
17.19951 篇4.167%
01.j clin oncol2 篇8.333%
02.acs sens1 篇4.167%
03.adv exp med biol1 篇4.167%
04.asian pac j cancer prev1 篇4.167%
05.biometrics1 篇4.167%
06.bjs open1 篇4.167%
07.bmc genomics1 篇4.167%
08.breast cancer res1 篇4.167%
09.breast cancer res treat1 篇4.167%
10.cancer causes control1 篇4.167%
01.美国13 篇54.167%
02.尼泊尔4 篇16.667%
03.德国2 篇8.333%
04.以色列2 篇8.333%
05.中国1 篇4.167%
06.埃及1 篇4.167%
07.奥地利1 篇4.167%
08.巴基斯坦1 篇4.167%
09.比利时1 篇4.167%
10.哈萨克斯坦1 篇4.167%
01.中国上海1 篇4.167%
02.中国深圳1 篇4.167%
01.Breast Neoplasms24 篇100.000%
02.Female23 篇95.833%
03.Humans23 篇95.833%
04.Adult6 篇25.000%
05.Aged6 篇25.000%
06.Middle Aged5 篇20.833%
07.Animals4 篇16.667%
08.Gene Expression Profiling4 篇16.667%
09.Survival Analysis4 篇16.667%
10.Antineoplastic Combined Chemotherapy Protocols3 篇12.500%

http://www.pubmedplus.cn/P/SearchQuickResult?wd=52cc16e4-0239-4d59-928b-020b32488c09

01.202214 篇6.306%
02.20219 篇4.054%
03.20208 篇3.604%
04.20199 篇4.054%
05.20189 篇4.054%
06.201710 篇4.505%
07.201610 篇4.505%
08.20155 篇2.252%
09.201411 篇4.955%
10.20135 篇2.252%
11.20124 篇1.802%
12.20116 篇2.703%
13.20108 篇3.604%
14.20097 篇3.153%
15.20087 篇3.153%
16.20076 篇2.703%
17.20067 篇3.153%
18.20055 篇2.252%
19.20049 篇4.054%
20.20035 篇2.252%
21.200210 篇4.505%
22.20019 篇4.054%
23.20006 篇2.703%
24.19993 篇1.351%
25.19983 篇1.351%
26.19973 篇1.351%
27.19964 篇1.802%
28.19955 篇2.252%
29.19942 篇0.901%
30.19933 篇1.351%
31.19923 篇1.351%
32.19911 篇0.450%
33.19902 篇0.901%
34.19881 篇0.450%
35.19861 篇0.450%
36.19851 篇0.450%
37.19831 篇0.450%
38.19811 篇0.450%
39.19761 篇0.450%
40.19732 篇0.901%
41.19721 篇0.450%
42.19684 篇1.802%
01.j biol chem19 篇8.559%
02.biosci rep7 篇3.153%
03.science7 篇3.153%
04.insect biochem mol biol6 篇2.703%
05.proc natl acad sci u s a6 篇2.703%
06.biophys j3 篇1.351%
07.chembiochem3 篇1.351%
08.environ res3 篇1.351%
09.genetics3 篇1.351%
10.lakartidningen3 篇1.351%
01.美国57 篇25.676%
02.瑞典55 篇24.775%
03.德国20 篇9.009%
04.英国17 篇7.658%
05.荷兰11 篇4.955%
06.中国7 篇3.153%
07.法国6 篇2.703%
08.日本6 篇2.703%
09.比利时5 篇2.252%
10.俄罗斯4 篇1.802%
01.中国北京2 篇0.901%
02.中国上海2 篇0.901%
03.中国天津1 篇0.450%
04.中国青岛1 篇0.450%
05.中国深圳1 篇0.450%
06.中国重庆1 篇0.450%
01.Humans125 篇56.306%
02.Mutation99 篇44.595%
03.Animals91 篇40.991%
04.Nobel Prize47 篇21.171%
05.History, 20th Century38 篇17.117%
06.Female31 篇13.964%
07.Mice27 篇12.162%
08.Amino Acid Sequence26 篇11.712%
09.Molecular Sequence Data26 篇11.712%
10.Neoplasms24 篇10.811%




https://blog.sciencenet.cn/blog-280034-1356771.html

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