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Head of Department of Cell Biology, Yale University
James E. Rothman, Head of Department of Cell Biology, Yale University, in memory of Ferguson F Wallace Professor of Biomedicine. He has won many honors, including the Louisa Gross Horvitz Prize of Columbia University, the Lasker Prize for Basic Medicine (2002), and the King Faisal Prize. He received a master's degree from Yale University and a doctor's degree from Harvard. He won the Nobel Prize in Physiology or Medicine in 2013.
耶鲁大学细胞生物学系系主任
詹姆斯·E·罗斯曼(JamesE.Rothman),耶鲁大学细胞生物学系系主任、纪念FergusF.Wallace生物医学教授。他曾获得多种荣誉,包括哥伦比亚大学的露依莎·格罗斯·霍维茨奖、拉斯克奖基础医学奖(2002年)、费萨尔国王奖。他在耶鲁大学取得硕士学位,在哈佛获博士学位。2013年获诺贝尔生理学或医学奖。
https://pubmed.ncbi.nlm.nih.gov/25087728/
Angew Chem Int Ed Engl
. 2014 Nov 17;53(47):12676-94.
doi: 10.1002/anie.201402380. Epub 2014 Aug 1.
Affiliations expand
PMID: 25087728
Cells contain small membrane-enclosed vesicles which transport many kinds of cargo between the compartments of the cell. The result is a choreographed program of secretory, biosynthetic, and endocytic protein traffic that serves the cell's internal physiologic needs.
Keywords: Nobel lecture; SNARE; cellular biology; membrane fusion; vesicle transport.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
The molecular machinery of neurotransmitter release (Nobel lecture).
Angew Chem Int Ed Engl. 2014 Nov 17;53(47):12696-717. doi: 10.1002/anie.201406359. Epub 2014 Oct 22.PMID: 25339369 Review.
In: Liedtke WB, Heller S, editors. TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades. Boca Raton (FL): CRC Press/Taylor & Francis; 2007. Chapter 23.PMID: 21204515 Free Books & Documents. Review.
[The source of membrane fusion in the cell].
Biol Aujourdhui. 2015;209(1):63-85. doi: 10.1051/jbio/2015010. Epub 2015 Jun 26.PMID: 26115713 French. No abstract available.
Nobel 2013 Physiology or medicine: Traffic control system within cells.
Nature. 2013 Dec 5;504(7478):98. doi: 10.1038/504098a.PMID: 24305158 No abstract available.
Med Sci (Paris). 2013 Nov;29(11):1055-8. doi: 10.1051/medsci/20112713024. Epub 2013 Nov 20.PMID: 24280511 French. No abstract available.
Screening of Hydrocarbon-Stapled Peptides for Inhibition of Calcium-Triggered Exocytosis.
Front Pharmacol. 2022 Jun 17;13:891041. doi: 10.3389/fphar.2022.891041. eCollection 2022.PMID: 35814209 Free PMC article.
Interspecies complementation identifies a pathway to assemble SNAREs.
iScience. 2022 Jun 2;25(7):104506. doi: 10.1016/j.isci.2022.104506. eCollection 2022 Jul 15.PMID: 35754735 Free PMC article.
Front Mol Biosci. 2021 Nov 10;8:740408. doi: 10.3389/fmolb.2021.740408. eCollection 2021.PMID: 34859048 Free PMC article.
An active tethering mechanism controls the fate of vesicles.
Nat Commun. 2021 Sep 14;12(1):5434. doi: 10.1038/s41467-021-25465-y.PMID: 34521845 Free PMC article.
AtSEC22 Regulates Cell Morphogenesis via Affecting Cytoskeleton Organization and Stabilities.
Front Plant Sci. 2021 Jun 4;12:635732. doi: 10.3389/fpls.2021.635732. eCollection 2021.PMID: 34149743 Free PMC article.
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