获得性遗传是法国生物学家拉马克首次提出的，1809年他在出版的《动物哲学》一书中系统阐述了最早的进化理论，他强调用进废退、获得性遗传和动物意志在进化中的重要作用。他在研究动物习性和器官的相互作用中，提出了两条著名的规律：用进废退和获得性遗传，就是说生物在个体发育中由于环境的影响或器官的用进废退获得了新性状，这种新的性状可以遗传给后代。他说：“某一环境约束的大变化，若在某种动物中成为恒常的变化，就会导出此等动物之新的习性是很明白的事。”同时指出机体因环境影响而获得的特征改变可以分为两大类：
https://baike.baidu.com/item/%E8%8E%B7%E5%BE%97%E6%80%A7%E9%81%97%E4%BC%A0/2030956
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| 06. | Mutation | 3034 篇 | 10.849% |
| 07. | Middle Aged | 2865 篇 | 10.244% |
| 08. | Mice | 2715 篇 | 9.708% |
| 09. | Molecular Sequence Data | 2413 篇 | 8.628% |
| 10. | Genetic Variation | 1990 篇 | 7.116% |
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