博文
化疗导致精子突变研究文献分析
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《Nature》意外发现化疗可能导致精子突变，甚至影响后代基因。超突变顾名思义，是一种突变频率明显高于正常突变的突变类型，通常以点突变的形式发生。
https://www.ebiotrade.com/newsf/2022-5/20220515065100398.htm
文献分析
http://www.pubmedplus.cn/P/SearchQuickResult?wd=ce21816f-5f11-47db-b54d-936b37a458eb
| 01. | 2020 | 1 篇 | 1.010% |
| 02. | 2019 | 1 篇 | 1.010% |
| 03. | 2015 | 3 篇 | 3.030% |
| 04. | 2010 | 2 篇 | 2.020% |
| 05. | 2009 | 1 篇 | 1.010% |
| 06. | 2008 | 2 篇 | 2.020% |
| 07. | 2006 | 1 篇 | 1.010% |
| 08. | 2005 | 2 篇 | 2.020% |
| 09. | 2004 | 1 篇 | 1.010% |
| 10. | 2002 | 5 篇 | 5.051% |
| 11. | 1999 | 8 篇 | 8.081% |
| 12. | 1998 | 11 篇 | 11.111% |
| 13. | 1997 | 7 篇 | 7.071% |
| 14. | 1996 | 10 篇 | 10.101% |
| 15. | 1995 | 8 篇 | 8.081% |
| 16. | 1994 | 2 篇 | 2.020% |
| 17. | 1993 | 1 篇 | 1.010% |
| 18. | 1992 | 3 篇 | 3.030% |
| 19. | 1991 | 1 篇 | 1.010% |
| 20. | 1990 | 5 篇 | 5.051% |
| 21. | 1989 | 1 篇 | 1.010% |
| 22. | 1988 | 3 篇 | 3.030% |
| 23. | 1987 | 2 篇 | 2.020% |
| 24. | 1984 | 1 篇 | 1.010% |
| 25. | 1983 | 1 篇 | 1.010% |
| 26. | 1980 | 1 篇 | 1.010% |
| 27. | 1979 | 1 篇 | 1.010% |
| 28. | 1978 | 2 篇 | 2.020% |
| 29. | 1976 | 1 篇 | 1.010% |
| 30. | 1975 | 2 篇 | 2.020% |
| 31. | 1974 | 1 篇 | 1.010% |
| 32. | 1973 | 2 篇 | 2.020% |
| 33. | 1972 | 2 篇 | 2.020% |
| 34. | 1971 | 1 篇 | 1.010% |
| 35. | 1970 | 2 篇 | 2.020% |
| 36. | 1969 | 1 篇 | 1.010% |
| 01. | hum reprod | 21 篇 | 21.212% |
| 02. | hum genet | 8 篇 | 8.081% |
| 03. | fertil steril | 6 篇 | 6.061% |
| 04. | mutat res | 6 篇 | 6.061% |
| 05. | cancer genet cytogenet | 4 篇 | 4.040% |
| 06. | j assist reprod genet | 4 篇 | 4.040% |
| 07. | environ mol mutagen | 2 篇 | 2.020% |
| 08. | j reprod fertil | 2 篇 | 2.020% |
| 09. | arch androl | 1 篇 | 1.010% |
| 10. | arch toxikol | 1 篇 | 1.010% |
| 01. | 美国 | 11 篇 | 11.111% |
| 02. | 加拿大 | 9 篇 | 9.091% |
| 03. | 西班牙 | 9 篇 | 9.091% |
| 04. | 比利时 | 6 篇 | 6.061% |
| 05. | 德国 | 6 篇 | 6.061% |
| 06. | 印度 | 5 篇 | 5.051% |
| 07. | 中国 | 4 篇 | 4.040% |
| 08. | 法国 | 4 篇 | 4.040% |
| 09. | 日本 | 4 篇 | 4.040% |
| 10. | 澳大利亚 | 3 篇 | 3.030% |
| 01. | 中国北京 | 2 篇 | 2.020% |
| 02. | 中国太原 | 1 篇 | 1.010% |
| 03. | 中国上海 | 1 篇 | 1.010% |
| 04. | 中国郑州 | 1 篇 | 1.010% |
| 01. | Chromosome Aberrations | 99 篇 | 100.000% |
| 02. | Male | 99 篇 | 100.000% |
| 03. | Spermatozoa | 99 篇 | 100.000% |
| 04. | Humans | 66 篇 | 66.667% |
| 05. | Animals | 49 篇 | 49.495% |
| 06. | Female | 48 篇 | 48.485% |
| 07. | Microinjections | 34 篇 | 34.343% |
| 08. | Mice | 29 篇 | 29.293% |
| 09. | Fertilization in Vitro | 28 篇 | 28.283% |
| 10. | Adult | 25 篇 | 25.253% |
https://blog.sciencenet.cn/blog-280034-1339564.html
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