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老药新用如虎添翼:樊嘉院士,朱棣,徐泱等团队提出肝癌免疫治疗新策略
http://www.ebiotrade.com/newsf/2022-4/2022412151741731.htm
2022年4月8日,复旦大学附属中山医院樊嘉院士、复旦大学朱棣研究员、复旦大学附属中山医院徐泱副教授课题组合作在Cancer Discovery (IF=39.40)在线发表题为 “Interferon-α potentiates anti-PD-1 efficacy by remodeling glucose metabolism in the hepatocellular carcinoma microenvironment” 的研究论文,该研究发现干扰素α可通过糖代谢重塑肿瘤免疫微环境激活免疫应答,克服免疫检查点抑制剂治疗(ICB)耐药,并提出两者联合治疗肝癌的新策略。
http://www.pubmedplus.cn/P/SearchQuickResult?wd=4a50572b-27ee-4723-9aa8-4684ae0db973
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