Barry J. Marshall(1951年9月30日~)澳大利亚科学家,与罗宾·沃伦(J. Robin Warren)发现了幽门螺杆菌(Helicobacter pylori,Hp)以及这种细菌在胃炎和胃溃疡等疾病中的作用,被授与2005年诺贝尔生理或医学奖。2011年,被评为中国工程院外籍院士。http://baike.so.com/doc/5612512-5825122.html
20世纪中叶,大多数医生认为胃溃疡是由于焦虑,辛辣食物或酸性物质过多引起的,而只能通过卧床休息,防酸片治疗,实在不行就要手术治疗。
然而在1979年,澳大利亚病理学家Robin Warren做胃组织炎症活检时发现出现有微小弯曲的细菌菌落存在。
另一位澳洲医生Barry Marshall得讯后和他联系组队,两人进行了100例胃溃疡活检。
他们的研究结果表明,细菌是导致胃溃疡和胃炎的原因,他们把这种细菌命名为幽门螺旋杆菌,但持怀疑态度的医学界认为他们的证据还不够充分。
因为没有动物适合作为人类这种疾病研究的替代模型,Barry 勇敢地喝下了含有细菌的培养液。五天后,他失去了胃口,然后每天早晨呕吐。内窥镜检查发现,他确实染上胃炎。Barry 然后开始一个疗程的抗生素,症状消失 (幽门螺旋杆菌引发胃溃疡,长期发展会导致胃癌几率大大提高。所以要及时治疗)。
http://blog.sciencenet.cn/blog-274385-1010458.html
PUBMED数据库检索到论文38篇
pubmed_result 38篇.txt
https://academic.microsoft.com/#/search?iq=Composite(AA.AuN%3D%3D'barry%20marshall')&q=barry%20marshall&filters=&from=0&sort=0
数据来源 http://www.pubmedplus.cn/
08.pacific grove 2 篇3.571% 09.戴维斯(加州大学戴维斯分校) 2 篇3.571% 查看更多
02.school of pathology 10 篇17.857% 03.sir charles gairdner hospital 4 篇7.143% 12.marshall centre for infectious disease research & training 1 篇1.786% 13.marshall centre for infectious disease research and training 1 篇1.786% 14.national cancer centre 1 篇1.786% 15.new england biolabs 1 篇1.786% 16.the university of western aus 1 篇1.786% 17.the university of western austra 1 篇1.786% 18.university of zurich 1 篇1.786% 23.哥德堡大学sahlgrenska学院 1 篇1.786% 28.苏格兰ninewells医院和医学院 1 篇1.786% 01.helicobacter pylori 32 篇57.143% 02.helicobacter infections 24 篇42.857% 03.gastric mucosa 6 篇10.714% 04.history, 20th century 6 篇10.714% 05.peptic ulcer 6 篇10.714% 06.bacterial proteins 4 篇7.143% 07.breath tests 4 篇7.143% 08.drug therapy, combination 4 篇7.143% 10.molecular sequence data 4 篇7.143% 12.stomach neoplasms 4 篇7.143% 13.anti-bacterial agents 3 篇5.357% 14.bacterial adhesion 3 篇5.357% 15.genome, bacterial 3 篇5.357% 16.history, 21st century 3 篇5.357% 20.stomach ulcer 3 篇5.357% 25.dietary supplements 2 篇3.571% 26.dna, bacterial 2 篇3.571% 27.duodenal ulcer 2 篇3.571% 28.enzyme-linked immunosorbent assay 2 篇3.571% 29.epithelial cells 2 篇3.571% 30.evolution, molecular 2 篇3.571% 32.food, fortified 2 篇3.571% 33.genes, reporter 2 篇3.571% 34.genetic vectors 2 篇3.571% 36.macaca mulatta 2 篇3.571% 37.mice, inbred c57bl 2 篇3.571% 39.protein structure, tertiary 2 篇3.571% 40.proton pumps 2 篇3.571% 41.rna, messenger 2 篇3.571% 42.sequence analysis, dna 2 篇3.571% 43.stomach diseases 2 篇3.571% 45.treatment outcome 2 篇3.571% 46.adaptation, biological 1 篇1.786% 47.adaptation, physiological 1 篇1.786% 48.adenocarcinoma 1 篇1.786% 49.adhesins, bacterial 1 篇1.786% 50.advisory committees 1 篇1.786% 01.bacterial proteins 4 篇7.143% 02.anti-bacterial agents 3 篇5.357% 05.dna, bacterial 2 篇3.571% 07.proton pumps 2 篇3.571% 08.rna, messenger 2 篇3.571% 10.1,2-dielaidoylphosphatidylethanolamine 1 篇1.786% 查看更多
24.先天性遗传性新生儿疾病和畸形 2 篇3.571% 01.school of pathology & laboratory medicine 6 篇10.714% 02.school of pathology and laboratory medicine 5 篇8.929% 03.department of gastroenterology 4 篇7.143% 04.department of medicine 4 篇7.143% 05.department of medical microbiology 3 篇5.357% 06.department of microbiology 3 篇5.357% 07.center for comparative medicine 2 篇3.571% 08.department of internal medicine 2 篇3.571% 09.department of pathology 2 篇3.571% 10.school of biomedical sciences 2 篇3.571% 11.school of chemistry and biochemistry 2 篇3.571% 12.1] center for comparative genomics and bioinformatics 1 篇1.786% 13.center for comparative genomics and bioinformatics 1 篇1.786% 14.center for microscopy and image analysis 1 篇1.786% 15.department of basic medical sciences 1 篇1.786% 16.department of biochemistry and microbiology 1 篇1.786% 17.department of biochemistry and molecular biology 1 篇1.786% 18.department of biomedical science 1 篇1.786% 19.department of biotechnology and bioinformatics 1 篇1.786% 20.department of food hygiene and environmental health 1 篇1.786% 21.department of medical biochemistry and cell biology 1 篇1.786% 22.department of medicine and microbiology 1 篇1.786% 23.department of molecular biology 1 篇1.786% 24.department of morphology 1 篇1.786% 25.department of neurology 1 篇1.786% 26.department of social and preventive medicine 1 篇1.786% 27.division of gastroenterology and hepatology 1 篇1.786% 28.institute of biomedicine 1 篇1.786% 29.institute of child health 1 篇1.786% 30.jean mayer usda human nutrition research center on aging at tufts university 1 篇1.786% 31.laboratory of pharmaceutical biotechnology 1 篇1.786% 32.new york university school of medicine and va medical center 1 篇1.786% 33.queen elizabeth medical center 1 篇1.786% 34.school of agriculture & food science 1 篇1.786% 35.school of biochemistry and immunology 1 篇1.786% 36.school of biomedical and chemical sciences 1 篇1.786% 37.school of biotechnology 1 篇1.786% 38.school of chemistry & biochemistry 1 篇1.786% 39.school of medicine and 1 篇1.786% 40.school of pathology 1 篇1.786% 41.school of pathology and laboratory medicine (m502) 1 篇1.786% 42.school of veterinary science 1 篇1.786% 43.united states of america ; center for comparative genomics and bioinformatics 1 篇1.786% 44.usa [2] california national primate research center 1 篇1.786% 45.usa [2] center for comparative genomics and bioinformatics 1 篇1.786% 46.vu university medical center 1 篇1.786%
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