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伟大的伯乐--苏新专 vs 屠呦呦的诺贝尔奖
伯乐--苏新专: Xin-zhuan Su, Ph.D.
National Institute of Allergy andInfectious Diseases
Chief, Malaria Functional Genomics Section
Laboratory of Malaria and Vector Research
Major Areas of Research
Plasmodium genetics and genomics
Host-parasite interaction and molecular signaling
Antimalarial drug development and mechanisms of drugresistance
Biography
Dr. Su received his Ph.D. inparasitology from the University of Georgia in 1990. He joined NIAID'sLaboratory of Parasitic Diseases in 1992 and became an investigator in the Laboratory of Malaria and Vector Research in 2001 and a senior investigator in 2006.
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Artemisinin:discovery from the Chinese herbal garden.
Miller LH, Su X.
Cell.2011 Sep 16;146(6):855-8. doi: 10.1016/j.cell.2011.08.024. Epub 2011 Sep 9.
Abstract
This year's Lasker DeBakey Clinical Research Award goes to Youyou Tu for the discovery of artemisinin and its use in the treatment of malaria--a medical advance that has saved millions of lives across the globe, especially in the developing world.
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http://life.xmu.edu.cn/s/161/t/566/24/f4/info140532.htm
苏新专 Su Xin-zhuan, Ph.D.
厦门大学“长江学者”讲座教授
(Adjunct Cheung Kong Professor, Xiamen University)
寄生原虫分子遗传学(Molecular Genetics of Parasitic Protozoa)
E-mail: xsu@niaid.nih.gov
Education and Career:
1982,B.Sc., 1985, M.S., Xiamen University;
1990, Ph.D., The University of Georgia, Athens;
1990-1992, Postdoctoral Fellow, the University ofGeorgia;
1992-2001, Staff Fellow, Senior Staff Fellow, StaffScientist;
2001-2006, Investigator; 2006-, Senior Investigator;
2011-, Senior Biomedical Research Service; National Institutes of Health, USA
(http://www.niaid.nih.gov/LABSANDRESOURCES/LABS/ABOUTLABS/
LMVR/MALARIAFUNCTIONALGENOMICSSECTION/Pages/su.aspx)
研究领域(Research Area)
本课题组以鼠疟原虫为模型,用遗传杂交、基因敲除、基因组测序和表达分析等方法来研究鼠疟原虫的抗药性、寄生虫在鼠和蚊子体内的发育相关的基因。近年来,我们开发了数百个用于约氏疟原虫基因分型的微卫星标记,建立了约氏疟原虫的第一张遗传图谱,开始了基因定位等工作。目前的工作主要是研究卵囊在蚊体内的发育和疟原虫的抗药性等。我们也关注其它有经济意义的寄生原虫如住白虫。
Our laboratory at Xiamen University consists of asmall number of people focusing on genetics of rodent malaria parasites. Wehave developed the first Plasmodiumyoelii linkage map and are using the map to identify genetic loci and genescontributing to drug resistance and parasite development in the rodent andmosquito hosts. Candidate genes will be verified using gene disruption andother biochemical, molecular, and cellular approaches. We are also interestedin other parasitic protozoa of economic importance such as Leucocytozoon of domestic birds.
厦大为第一或通讯作者单位的论文(Publications by students of Xiamen University)
1. LiJ, YuanJ,Chen CC, Inglese J, Su X-z*:Chemical genomics for studying parasite gene function and interaction. Trendsin Parasitol 2013 (In press).
2. Qi Y, Zhu F, Li J, Fu Y,Pattaradilokrat S, Hong L, Liu S, Huang F, Xu W*, Su X-z*: Optimized protocols for improving the likelihood ofcloning recombinant progeny from Plasmodiumyoelii genetic crosses. Exp Parasitol 2013, 113(1):44-50.
3. Zhang Y, Miura K*, Li J, TulloG, Zhu F, Hong L, Lin T, Su X-z,Long C: Macrophage migration inhibitory factor homolog from Plasmodium yoelii modulates monocyterecruitment and activation in spleen during infection. Parasitol Res 2012,110(5): 1755-1763.
4. Zhang Y, Qi Y, Li J, Liu S,Hong L, Lin T, Long C, Su X-z*: Anew malaria antigen produces partial protection against Plasmodium yoelii challenge. Parasitol Res 2012,110(4):1337-1345.
5. Li J, Pattaradilokrat S, ZhuF, Jiang H, Liu S, Hong L, Fu Y, Koo L, Xu W, Pan W, Carlton JM, Kaneko O,Carter R, Wootton JC, Su X-z*:Linkage maps from multiple genetic crosses and loci linked to growth-relatedvirulent phenotype in Plasmodium yoelii.ProcNatl Acad Sci USA 2011, 108(31): E374-E382.
6. Li J, Zhang Y, Liu S, Hong L,Sullivan M, McCutchan TF, Carlton JM, SuX-z*: Hundreds of microsatellites for genotyping Plasmodium yoelii parasites. Mol Biochem Parasitol 2009,166(2):153-158.
7. Li J, Zhang YH, Sullivan M,Hong LX, Huang L, Lu FL, McCutchan TF, SuX-z*: Typing Plasmodium yoeliimicrosatellites using a simple and affordable fluorescent labeling method. MolBiochem Parasitol 2007, 155(2):94-102.
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http://news.sciencenet.cn/htmlnews/2015/10/328115.shtm
屠呦呦获2015年诺贝尔生理学或医学奖
作者:张笑梅进赵河雨来源:科学网www.sciencenet.cn发布时间:2015/10/517:33:15
http://news.sciencenet.cn/html/comment.aspx?id=328115
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http://news.sciencenet.cn/htmlnews/2015/10/328133.shtm
林小春杨骏来源:新华国际发布时间:2015/10/615:28:10
揭秘屠呦呦美国推荐人:2010年起年年推荐
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饶毅是屠呦呦得奖的大功臣确是无稽之谈
http://blog.sciencenet.cn/blog-266190-926069.html
http://blog.sina.com.cn/s/blog_502041670102dvd3.html
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2011-9-19博文:屠呦呦的1971年10月4日:让我们记住这一天
http://blog.sciencenet.cn/blog-453765-925651.html
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[1]孙启高 2015-10-6 04:27
苏新专
在拉斯克奖颁奖期间陪同屠呦呦的美国国家卫生研究院疟疾研究室研究员苏新专认为,从青蒿到抗疟药,各种各样人的贡献肯定少不了,但拉斯克奖并没有颁给整个组织,这是因为“作为一个鼓励科学发现的奖项,拉斯克奖倾向于只授予最初始的发现者”。http://www.wenxuecity.com/news/2015/10/05/4613354.html
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可贵而幸运的“1”----有感于高锟获诺贝尔奖
http://blog.sciencenet.cn/blog-225931-260713.html
2009-10-9 12:12
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