Research papers that are selected for in-depth review are evaluated by at least two outside reviewers, who are contacted before being sent a paper and asked to return comments within 2 weeks in most cases. Once all reviews are in, we initiate a cross-review process in which we invite all reviewers to read the other (still anonymous) reviews and make additional comments within 2 business days. Cross-review is encouraged, but not required. We are able to expedite the review process significantly for papers that require rapid assessment. Manuscripts selected for publication are edited to improve accuracy and clarity, as well as for length. Rejected papers cannot be resubmitted over a disagreement on novelty, interest, or relative merit. If a paper was rejected on the basis of serious reviewer error, resubmission may be considered.