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博文

与Englerin衍生物有关的几条专利文献

已有 3483 次阅读 2012-11-8 09:17 |个人分类:药物动态|系统分类:博客资讯| 专利, 肾癌, 抗癌药, 衍生物, englerin

     有人询问对于肾癌细胞具有抑制生长作用的Englerin A衍生物是否有专利申请,结果有关专利文献数据库进行不全面的简要检索,得到了几项相关专利文献,有美国专利。欧洲专利、世界专利组织的专利,具体内容加下:

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Document Title

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1

WO/2011/120886A1

A PROCESS FOR THE PREPARATION OF (-)-ENGLERIN A, AND ANALOGUES AND INTERMEDIATES THEREOF  
It is provided a process for the preparation of (-)-englerin A, as well as analogous compounds thereof, the process comprising transforming a compound of formula (II) wherein PG1 is an ether...

1000

2

WO/2012/084267A1

DERIVATIVES OF ENGLERIN FOR THE TREATMENT OF CANCER  
The present invention relates to compounds of the general Formula (I), which show a specific activity against cancer cell lines, the use of these compounds for prophylaxis and treatment of cancer...

630

3

WO/2009/088854A1

EPOXY-GUAIANE DERIVATIVES AND TREATMENT OF CANCER  
Disclosed are englerins and derivatives (I) thereof useful in the treatment of a number of cancers, particularly renal cancer, as well as pharmaceutical compositions and method of treating a...

410

4

EP2474550A1

Derivatives of Englerin for the treatment of cancer  
The present invention relates to compounds of the general formula (I) which show a specific activity against cancer cell lines, the use of these compounds for prophylaxis and treatment of cancer as...

407

5

US20100286259

EPOXY-GUAIANE DERIVATIVES AND TREATMENT OF CANCER  
Disclosed are englerins and derivatives (I) thereof useful in the treatment of a number of cancers, particularly renal cancer, as well as pharmaceutical compositions and method of treating a...

379

6

EP2235021B1

EPOXY-GUAIANE DERIVATIVES AND TREATMENT OF CANCER  

120



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