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Based on an unprecedented 75 years longitudinal study known as the  Harvard Grant Study:

What keeps us happy and healthy as we go through life? If you think it's  fame and money, you're not alone – but,according to psychiatrist  Robert Waldinger, you're mistaken. As the director of a 75-year-old study on adult development, Waldinger has unprecedented access to data on true happiness and satisfaction. In this talk, he shares three important lessons learned from the study as well as some practical,old-as-the-hills wisdom on how to build a fulfilling, long life.

This 13 minutes video is well worth watching  http://www.ted.com/talks/robert_waldinger_what_makes_a_good_life_lessons_from_the_longest_study_on_happiness