华中农业大学高层次引进人才津田賢一（Kenichi Tsuda）教授

团队招收多名博士后

·         导师介绍

          津田賢一（Kenichi Tsuda）， 华中农业大学二级教授，此前在德国马克思-普朗克研究所-植物育种所（Max Planck Institute for Plant Breeding Research）工作。他于1995年-2004年在日本北海道大学获得学士，硕士和博士学位； 2005年-2010年在美国明尼苏达大学从事博士后研究；2011年-至今，在德国马克思-普朗克研究所-植物育种所担任Group Leader。2019年被华中农业大学以高水平人才引进在植物科学技术学院及农业微生物学国家重点实验室工作。

          Tsuda博士致力于植物免疫网络结构和动力学的研究，主要以拟南芥为研究对象，研究方向涉及植物病原微生物互作、植物免疫中的激素网络、植物转录重编程、气孔孔径调控、生物胁迫和非生物胁迫相互作用以及MAPK信号通路等许多方面。为了更好理解植物免疫如何影响细菌防御行为，Tsuda 博士建立了一种从感染的病原菌的植物叶中分离细菌mRNA进行RNA-seq 的研究方法，植物与细菌的双重转录组分析有助于全面了解植物与细菌之间的相互作用。至今，Tsuda 博士已在Cell Host & Microbe、Nature Communication、PNAS、Plant Cell、The EMBO Journal 、EMBO Reports、Plos Genetics、New Phytologist、Plant Physiology、Genome Biology 、Plant Journal、Annual Review of Plant Biology、Annual Review of Phytopathology、Current Opinion in Plant Biology等期刊发表论文60余篇。其中，近5年聚焦植物病原微生物互作机制研究，发表高水平SCI学术论文32篇，其中通讯及第一作者16篇，Tsuda博士有7篇高被引论文，总他引次数2613次，H影响因子为27。应邀参加国际学术会议83次，其中大会报告或特邀报告12次、分会场主持3次，应邀到全球25个学术机构进行学术交流。

      课题组网站：      https://www.mpipz.mpg.de/tsuda

                            http://cpst.hzau.edu.cn/info/1015/4777.htm

·        应聘条件

1、  具有或即将获得生物信息学、分子生物学、植物学或相近专业博士学位；

2、  博士期间发表较高水平SCI论文1-2篇以上；

3、  具有较强的英语阅读和写作能力。

4、  责任心强，沟通及表达能力强，具有团队精神。

  ·         应聘者提供的材料

1、  个人英文简历，其中包括反映本人学术水平的代表性成果；

2、  未来初步研究计划；

3、  2-3封专家推荐信。

如有意向了解更多信息可发送邮件至Kenichi Tsuda邮箱：tsuda@mpipz.mpg.de 或联系Kenichi Tsuda博士研究生曹禺：cao@mpipz.mpg.de.

In the group of Kenichi Tsuda at the Huazhong Agricultural University （HZAU）in Wuhan, China,

Postdoctoral positions in Bioinformatics/Plant Biology/Molecular Biology

will be available immediately.

We seek a motivated candidate with a PhD in bioinformatics and/or plant molecular biology (biology). Experience with Arabidopsis and microbe interactions is desirable but not required.

Applicants should have published research results in peer-reviewed high quality journals, demonstrated creativity, independence, high motivation, good communication skills, and the ability to work independently as well as with other members of our research group.

The candidate will work in a project aiming to:

(1) Understand molecular mechanisms underlying the plant interactions with pathogenic and commensal bacteria and microbiota.

(2) Understand molecular mechanisms underlying the complex nature of the plant immune network using a variety of genetic resources and genomics approaches.

(3) Understand plant immune network structures, properties and dynamics with evolutionary aspects using Arabidopsis relatives and natural pathogens.

Please see our website (https://www.mpipz.mpg.de/tsuda，http://cpst.hzau.edu.cn/info/1015/4777.htm ) or contact Kenichi Tsuda (tsuda@mpipz.mpg.de) or Tsuda’s group PhD student Yu Cao (cao@mpipz.mpg.de) by e-mail for details.

Please send your application including (i) a cover letter summarizing your qualifications and your motivation to work on these projects, (ii) a CV with a full publication list, and (iii) names and contacts of two to three references. The application should be submitted electronically as one pdf file to Dr. Kenichi Tsuda (tsuda@mpipz.mpg.de)

Review of applications will begin immediately and continue until the position is filled.

Selected publications

Wang Y, Garrido-Oter R, Wu J, Winkelmuller TM, Agler M, Colby T, Nobori T, Kemen E, Tsuda K*: Site-specific cleavage of bacterial MucD by secreted proteases mediates antibacterial resistance in Arabidopsis. Nature Communications, in press (2019) *corresponding author

Nobori T, Tsuda K*: The plant immune system in heterogeneous environments. Current Opinion in Plant Biology, 50: 58-66 (2019) *corresponding author

Berens ML, Wolinska KW, Spaepen S, Ziegler J, Nobori T, Nair A, Krüler V, Winkelmüller TM, Wang Y, Mine A, Becker D, Garido-Oter R, Schulze-Lefert P*, Tsuda K*: Balancing trade-offs between biotic and abiotic stress responses through leaf age-dependent variation in stress hormone crosstalk. Proceedings of the National Academy of Sciences USA, 116: 2364-2373 (2019) *corresponding author

Wang Y, Schuck S, Wu J, Yang P, Döring AC, Zeier J*, Tsuda K*: A MPK3/6-WRKY33-ALD1-Pipecolic acid Regulatory Loop Contributes to Systemic Acquired Resistance. Plant Cell, 10: 2480-2494 (2018) *corresponding author,  Highlighted in Castroverde Plant Cell, 10: 2238-2239 (2018)

Nobori T and Tsuda K*: In planta Transcriptome Analysis of Pseudomonas syringae. Bio-protocol, 8: 2987 (2018) *corresponding author

Mine A, Seyfferth C, Kracher B, Berens ML, Becker D, Tsuda K*: The Defense Phytohormone Signaling Network Enables Rapid, High-amplitude Transcriptional Reprogramming During Effector-Triggered Immunity. Plant Cell, 30: 1199-1219 (2018) *corresponding author

Nobori T, Mine A, Tsuda K*: Molecular networks in plant-pathogen holobiont. FEBS Letters, 592: 1937-1953 (2018) *corresponding author

Nobori T, Velásquez AC, Wu J, Kvitko BH, Kremer JM, Wang Y, He SY*, Tsuda K*: Transcriptome landscape of a bacterial pathogen under plant immunity. Proceedings of the National Academy of Sciences USA,115: E3055-E3064 (2018) *corresponding author, Spotlighted in Cohen et al Trends Plant Sci, 23: 751-753 (2018)

Jacob F, Kracher B, Mine A, Seyfferth C, Blanvillain-Baufume S, Parker JE, Tsuda K, Schulze-Lefert P, Maekawa T: A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytologist, 217: 1667-1680 (2018)

Huot B, Castroverde CDM, Velásquez AC, Hubbard E, Pulman JA, Yao J, Childs KL, Tsuda K, Montgomery BL, He SY: Dual impact of elevated temperature on plant defence and bacterial virulence in Arabidopsis. Nature Communications, 8: 1808 (2017)

Berens ML, Berry HM, Mine A, Argueso CT, Tsuda K*: Evolution of Hormone Signaling Networks in Plant Defense. Annual Review of Phytopathology, 55: 401-425 (2017) *corresponding author

Mine A, Berens ML, Nobori T, Anver S, Fukumoto K, Winkelmüller TM, Takeda A, Becker D, Tsuda K*: Pathogen exploitation of an abscisic acid- and jasmonate-inducible MAPK phosphatase and its interception by Arabidopsis immunity. Proceedings of the National Academy of Sciences USA, 114: 7456-7461 (2017) *corresponding author

Shigenaga AM, Berens ML, Tsuda K*, Argueso CT*: Towards Engineering of Hormonal Crosstalk in Plant Immunity. Current Opinion in Plant Biology, 38: 164-172 (2017) *corresponding author

Hillmer R, Tsuda K, Rallapalli G, Asai S, Truman W, Papke MD, Sakakibara H, Jone JDG, Myers CL, Katagiri F: The Highly Buffered Arabidopsis Immune Signaling Network Conceals the Functions of its Components. PLoS Genetics, 13: e1006639 (2017) Featured in Brett M Tyler PLoS Genetics 13: e1006713 (2017)

Mine A, Nobori T†, Salazar-Rondon MC†, Winkelmüller TM, Anver S, Becker D, Tsuda K*: An incoherent feed-forward loop mediates robustness and tunability in a plant immune network. EMBO Reports, 18: 464-476 (2017) *corresponding author

Yamada K, Yamaguchi K, Shirakawa T, Nakagami H, Mine A, Ishikawa K, Fujiwara M, Narusaka M, Narusaka Y, Ichimura K, Kobayashi Y, Matsui H, Nomura Y, Nomoto M, Tada Y, Fukao Y, Fukamizo T, Tsuda K, Shirasu K, Shibuya N, Kawasaki T: The CERK1-associated kinase PBL27 mediates chitin-triggered MAPK activation in Arabidopsis. The EMBO Journal, 35: 2468-2483 (2016)

Stuttmann J, Peine N, Garcia AV, Wagner C, Choudhury SR, Wang Y, James GV, Griebel T, Alcazar R, Tsuda K, Schneeberger K, Parker JE: Arabidopsis thaliana DM2h (R8) within the Landsberg RPP1-like Resistance Locus Underlies Three Different Cases of EDS1-Conditioned Autoimmunity. PLoS Genetics, 12: e1005990 (2016)

Yamada K, Yamashita-Yamada M, Hirase T, Fujiwara T, Tsuda K, Hiruma K, Saijo Y: Danger peptide receptor signaling in plants ensures basal immunity upon pathogen-induced depletion of BAK1. The EMBO Journal, 35: 46-61 (2016)

Cui H, Tsuda K, Parker JE: Effector-Triggered Immunity: From Pathogen Perception to Robust Defense. Annual Review of Plant Biology, 66: 487-511 (2015)

Mateos JL, Madrigal P, Tsuda K, Richter R, Rawat V, Romera-Branchat M, Fornara F, Schneeberger K, Krajewski P, Coupland G: Decoded combinatorial activities of SHORT VEGETATIVE PHASE and FLOWERING LOCUS C define distinct modes of flowering regulation in Arabidopsis. Genome Biology, 16: 31 (2015)

Tsuda K* and Somssich IE*: Transcriptional networks in plant immunity. New Phytologist, 206: 932-947 (2015) *corresponding author

Anver S and Tsuda K*: Ethylene and Plant Immunity. In Ethylene in Plants. Ed.: Chi-Kuang Wen. Springer Science+Business Media, Dordrecht Heidelberg New York London, 205-221 (2015) *corresponding author

Seyfferth C and Tsuda K*: Salicylic acid signal transduction: the initiation of biosynthesis, perception and transcriptional reprogramming. Frontiers in Plant Science, 5: 697 (2014) *corresponding author

Mine A, Sato M, Tsuda K*: Toward a systems understanding of plant--microbe interactions. Frontiers in Plant Science, 5: 423 (2014) *corresponding author

Kim Y, Tsuda K, Igarashi D, Hillmer RA, Sakakibara H, Myers CL, Katagiri F: Mechanisms underlying robustness and tunability in a plant immune signaling network. Cell Host & Microbe, 15: 84-94 (2014)

Ross A, Yamada K, Hiruma K, Yamashita-Yamada M, Lu Xunli, Takano Y, Tsuda K, Saijo Y: The Arabidopsis PEPR pathway couples local and systemic plant immunity. The EMBO Journal, 33: 62-75 (2014)

Tsuda K*, Mine A, Bethke G, Igarashi D, Botanga CJ, Tsuda Y, Glazebrook J, Sato M, Katagiri F: Dual regulation of gene expression mediated by extended MAPK activation and salicylic acid contributes to robust innate immunity in Arabidopsis thaliana. PLoS Genetics, 9: e1004015 (2013) *corresponding author

Tintor N, Ross A, Kanehara K, Yamada K, Fan L, Kemmerling B, Nurnberger T, Tsuda K, Saijo Y: Layered pattern receptor signaling via ethylene and endogenous elicitor peptides during Arabidopsis immunity to bacterial infection. Proceedings of the National Academy of Sciences USA, 110: 6211-6216 (2013)

Igarashi D, Tsuda K, Katagiri F: The Peptide Growth Factor, Phytosulfokine, Attenuates Pattern-Triggered Immunity. The Plant Journal, 71: 194-204 (2012)

Tsuda K, Qi Y, Nguyen LV, Bethke G, Tsuda Y, Glazebrook J, Katagiri F: An efficient Agrobacterium-mediated transient transformation of Arabidopsis. The Plant Journal, 69: 713-719 (2012)

Willmann R, Lajunena HM, Erbsb G, Newman M, Kolb D, Tsuda K, Katagiri F, Fliegmann J, Bono J, Cullimore JV, Jehle AK, Gotz F, Kulikh A, Molinaroi A, Lipka V, Gust AA, Nurnberger T: The Arabidopsis LYM1 LYM3 CERK1 pattern recognition system mediates bacterial peptidoglycan sensing and immunity to bacterial infection. Proceedings of the National Academy of Sciences USA, 108: 19824-19829 (2011)

Qi Y, Tsuda K, Nguyen LV, Wang X, Lin J, Murphy AS, Glazebrook J, Thordal-Christensen H, Katagiri F: Physical association of Arabidopsis hypersensitive induced reaction proteins (HIRs) with the immune receptor RPS2. Journal of Biological Chemistry, 286: 31297-31307 (2011)

Wang L, Tsuda K, Truman W, Sato M, Nguyen LV, Katagiri F, Glazebrook J: CBP60g and SARD1 play partially redundant, critical roles in salicylic acid signaling. The Plant Journal, 67: 1029-1041 (2011)

Qi Y, Tsuda K, Glazebrook J, Katagiri F: Physical association of PTI and ETI immune receptors in Arabidopsis. Molecular Plant Pathology, 12: 702-708 (2011)

Katagiri F, Tsuda K: Understanding the plant immune system. Molecular Plant-Microbe Interactions, 23: 1531-1536 (2010)

Tsuda K, Katagiri F: Comparing signaling mechanisms engaged in pattern-triggered and effector-triggered immunity. Current Opinion in Plant Biology, 13: 459-465 (2010)

Sato M, Tsuda K, Wang L, Coller J, Watanabe Y, Glazebrook J, Katagiri F: Network modeling reveals prevalent negative regulatory relationships between signaling sectors in Arabidopsis immune signaling. PLoS Pathogens, 6: e1001011 (2010)

Tsuda K, Sato M, Stoddard T, Glazebrook J, Katagiri F: Network properties of robust immunity in plants. PLoS Genetics, 5: e1000772 (2009)

Wang L, Tsuda K, Sato M, Cohen JD, Katagiri F, Glazebrook J: Arabidopsis CaM binding protein CBP60g contributes to MAMP-induced SA accumulation and is involved in disease resistance against Pseudomonas syringae. PLoS Pathogens, 5: e1000301 (2009)

Tsuda K, Sato M, Glazebrook J, Cohen JD, Katagiri F: Interplay between MAMP-triggered and SA-mediated defense responses. The Plant Journal, 53: 763-775 (2008)