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Cover image: Environmental pollution is one of the greatest challenges the world is facing today. Multi-disciplinary approaches are essential to solve complex environmental problems. The Special Topic in this issue (page 409–462) summarizes major research programs and progress made in addressing environmental pollution and health risk in China and beyond. Image design: Xiaoling Yu.

Table of Contents (Volume 3 Issue 4 December 2016)

EDITORIAL

Mu-ming Poo

Scientific leap-forward in the critical period: the thirteenth Five-Year Plan of the Chinese Academy of Sciences (CAS)

Natl Sci Rev (2016) 3 (4): 393. DOI: 10.1093/nsr/nww075

https://doi.org/10.1093/nsr/nww075

RESEARCH HIGHLIGHTS

PHYSICS

Li You

Viewpoint on optical frequency divider with 10^(-21) precision

Natl Sci Rev (2016) 3 (4): 394-395. DOI: 10.1093/nsr/nww085

https://doi.org/10.1093/nsr/nww085

Nan-Lin Wang

The discovery of a quantum Griffiths singularity in superconducting films

Natl Sci Rev (2016) 3 (4): 396-397. DOI: 10.1093/nsr/nww077

https://doi.org/10.1093/nsr/nww077

GEOSCIENCES

Bojie Fu; Yan Li

Bidirectional coupling between the Earth and human systems is essential for modeling sustainability

Natl Sci Rev (2016) 3 (4): 398-399. DOI: 10.1093/nsr/nww094

https://doi.org/10.1093/nsr/nww094

Yuan Gao

Editors’ selection of papers from China's academic journals

Natl Sci Rev (2016) 3 (4): 399-400. DOI: 10.1093/nsr/nww088

https://doi.org/10.1093/nsr/nww088

PERSPECTIVES

GEOSCIENCES

Mattias Hallquist; John Munthe; Min Hu; Tao Wang; Chak K Chan; Jian Gao; Johan Boman;  Song Guo; Åsa M Hallquist; Johan Mellqvist; Jana Moldanova; Ravi K Pathak; Jan BC Pettersson; Håkan Pleijel; David Simpson; Marie Thynell

Photochemical smog in China: scientific challenges and implications for air-quality policies

Natl Sci Rev (2016) 3 (4): 401-403. DOI: 10.1093/nsr/nww080

https://doi.org/10.1093/nsr/nww080

SCIENCE POLICY

Junling Huang; Dongbo Shi; Lan Xue; Venkatesh Narayanamurti

A case study of a world-class research project accomplished in China: discovery of the quantum anomalous Hall effect

Natl Sci Rev (2016) 3 (4): 405-409. DOI: 10.1093/nsr/nww068

https://doi.org/10.1093/nsr/nww068

Special Topic: Environmental Pollution and Health Risk

GUEST EDITORIAL

Guibin Jiang

Preface to the special topic on environmental pollution and health risk

Natl Sci Rev (2016) 3 (4): 409. DOI: 10.1093/nsr/nww090

https://doi.org/10.1093/nsr/nww090

RESEARCH HIGHLIGHTS

ENVIRONMENT/ECOLOGY

Qian Liu; Holger Hintelmann; Guibin Jiang

Natural stable isotopes: new tracers in environmental health studies

Natl Sci Rev (2016) 3 (4): 410. DOI: 10.1093/nsr/nww054

https://doi.org/10.1093/nsr/nww054

Zhe Li; Hailin Wang

DNA N6-methyladenine modification: a new role for epigenetic silencing in mammalian

Natl Sci Rev (2016) 3 (4): 412. DOI: 10.1093/nsr/nww052

https://doi.org/10.1093/nsr/nww052

PERSPECTIVES

ENVIRONMENT/ECOLOGY

Liang-Hong Guo

Haze and health

Natl Sci Rev (2016) 3 (4): 412-413. DOI: 10.1093/nsr/nww071

https://doi.org/10.1093/nsr/nww071

Yongyi Wei; Bing Yan

Nano products in daily life: to know what we do not know

Natl Sci Rev (2016) 3 (4): 415-416. DOI: 10.1093/nsr/nww073

https://doi.org/10.1093/nsr/nww073

REVIEWS

ENVIRONMENT/ECOLOGY

Tian Xia; Yifang Zhu; Lina Mu; Zuo-Feng Zhang; Sijin Liu

Pulmonary diseases induced by ambient ultrafine and engineered nanoparticles in twenty-first century

Natl Sci Rev (2016) 3 (4): 416-429. DOI: 10.1093/nsr/nww064

https://doi.org/10.1093/nsr/nww064

PHARMACOLOGY & TOXICOLOGY

Xinglei Yao; Nuoya Yin; Francesco Faiola

Stem cell toxicology: a powerful tool to assess pollution effects on human health

Natl Sci Rev (2016) 3 (4): 430-450. DOI: 10.1093/nsr/nww089

https://doi.org/10.1093/nsr/nww089

ENVIRONMENT/ECOLOGY

Aleksandra Popowich; Qi Zhang; X. Chris Le

Arsenobetaine: the ongoing mystery

Natl Sci Rev (2016) 3 (4): 451-458. DOI: 10.1093/nsr/nww061

https://doi.org/10.1093/nsr/nww061

INTERVIEW

Li Xu; Bin Zhao

Global environmental health: an interview with Sally Perreault Darney

Natl Sci Rev (2016) 3 (4): 459-462. DOI: 10.1093/nsr/nww095

https://doi.org/10.1093/nsr/nww095

RESEARCH ARTICLE

PHYSICS

Yuan Yao; Yanyi Jiang; Hongfu Yu; Zhiyi Bi; Longsheng Ma

Optical frequency divider with division uncertainty at the 10^(−21) level

Natl Sci Rev (2016) 3 (4): 463-469. DOI: 10.1093/nsr/nww063

https://doi.org/10.1093/nsr/nww063

REVIEWS

MULTIDISCIPLINARY

Safa Motesharrei; Jorge Rivas; Eugenia Kalnay; Ghassem R. Asrar; Antonio J. Busalacchi;  Robert F. Cahalan; Mark A. Cane; Rita R. Colwell; Kuishuang Feng; Rachel S. Franklin; Klaus Hubacek; Fernando Miralles-Wilhelm; Takemasa Miyoshi; Matthias Ruth; Roald Sagdeev; Adel Shirmohammadi; Jagadish Shukla; Jelena Srebric; Victor M. Yakovenko; Ning Zeng

Modeling sustainability: population, inequality, consumption, and bidirectional coupling of the Earth and Human Systems

Natl Sci Rev (2016) 3 (4): 470-494. DOI: 10.1093/nsr/nww081

https://doi.org/10.1093/nsr/nww081

GEOSCIENCES

Yong-Fei Zheng; Yi-Xiang Chen

Continental versus oceanic subduction zones

Natl Sci Rev (2016) 3 (4): 495-519. DOI: 10.1093/nsr/nww049

https://doi.org/10.1093/nsr/nww049

CHEMISTRY

Xue Wang; Aleksey Ruditskiy; Younan Xia

Rational design and synthesis of noble-metal nanoframes for catalytic and photonic applications

Natl Sci Rev (2016) 3 (4): 520-533. DOI: 10.1093/nsr/nww062

https://doi.org/10.1093/nsr/nww062

INTERVIEW

Ling Wang; Mu-ming Poo

Peidong Yang: cultivating ground-breaking research in China

Natl Sci Rev (2016) 3 (4): 534-537. DOI: 10.1093/nsr/nww086

https://doi.org/10.1093/nsr/nww086

FORUM

Jane Qiu

Research and development of artificial intelligence in China

Natl Sci Rev (2016) 3 (4): 538-541. DOI: 10.1093/nsr/nww076

https://doi.org/10.1093/nsr/nww076