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不平凡的2020年已经过去,但人类与SARS-CoV-2之间的战役仍在继续。临床数据显示,SARS-CoV-2可以从肺入侵到其他多个器官,包括心血管、肝脏、肾脏、肠道以及大脑,不仅引起COVID-19,相关并发症同样不容忽视。
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Editorial│SARS-CoV-2 and its infected world Editor-in-Chief: Jiarui Wu Highlight│A promiscuous interaction of SARS-CoV-2 with bacterial products Authors: Guillaume Carissimo, Lisa F P Ng Article│SARS-CoV-2 spike protein binds to bacterial lipopolysaccharide and boosts proinflammatory activity First Authors: Ganna Petruk, Manoj Puthia Corresponding Author: Artur Schmidtchen Keywords: COVID-19, SARS-CoV-2, spike protein, lipopolysaccharide, inflammation, aggregation, metabolic syndrome Article│Histone deacetylase 4 inhibits NF-κB activation by facilitating IκBα sumoylation First Author: Qi Yang Corresponding Author: Jizheng Chen Keywords: histone deacetylase 4, sumoylation, IκBα, NF-κB, SUMO E3 ligase Article│Proteome-wide data analysis reveals tissue-specific network associated with SARS-CoV-2 infection First Authors: Li Feng, Yuan-Yuan Yin Corresponding Authors: Jiarui Wu, Rong Zeng Keywords: SARS-CoV-2, proteome-wide, tissue-specific Perspective│COVID-19 and diabetes: the contributions of hyperglycemia First Author: Jing Wang Corresponding Author: Wen Meng Perspective│SARS-CoV-2 infection and the antiviral innate immune response Authors: Hui Yang, Yingying Lyu, Fajian Hou Review│Cytoskeleton—a crucial key in host cell for coronavirus infection First Authors: Zeyu Wen, Yue Zhang Corresponding Author: Yaming Jiu Keywords: coronavirus, host cytoskeleton, actin filaments, microtubules, intermediate filaments, pathology Review│The development of neutralizing antibodies against SARS-CoV-2 and their common features First Author: Liu Daisy Liu Corresponding Authors: Leng-Siew Yeap, Fei-Long Meng Keywords: COVID-19, SARS-CoV-2, neutralizing antibody, epitope, RBD Application Note│Rapid quantitative screening assay for SARS-CoV-2 neutralizing antibodies using HiBiT-tagged virus-like particles First Author: Kei Miyakawa Corresponding Author: Akihide Ryo
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