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Nature neurosci——MD-PFC环路参与工作记忆的维持
Abstract
1.Reciprocal MD–mPFC activity is required for spatial working memory.
2.Discrete task phases depend on distinct MD–mPFC interactions.
3.MD–mPFC functional directionality dynamically shifts across task phases.
4.mPFC spatial tuning is absent during the delay phase and independent of MD input.
5.Delay-elevated mPFC neurons exhibit temporally sparse and sequential activity that tiles the delay phase.
6.Delay-elevated mPFC activity is diminished on incorrect trials and selectively depends on MD inputs.
7.MD activity sustains mPFC delay activity in an input and task phase specific manner.
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Nature neurosci——MD-PFC环路参与工作记忆的维持
Abstract
1.Reciprocal MD–mPFC activity is required for spatial working memory.
2.Discrete task phases depend on distinct MD–mPFC interactions.
3.MD–mPFC functional directionality dynamically shifts across task phases.
4.mPFC spatial tuning is absent during the delay phase and independent of MD input.
5.Delay-elevated mPFC neurons exhibit temporally sparse and sequential activity that tiles the delay phase.
6.Delay-elevated mPFC activity is diminished on incorrect trials and selectively depends on MD inputs.
7.MD activity sustains mPFC delay activity in an input and task phase specific manner.
经典文章回顾
你对老年性痴呆症到底懂多少?
喜欢我,关注我
拉到最上方标题下,点击上方蓝字关注
搜索公众号名称:神经科学临床和基础
也请你推荐给你身边的医学朋友,感谢你~
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