博文
Cell Reports第一期第一卷出来了
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生物通报道：《Cell》杂志创刊于1976年，以发表具有重要意义的原创性科研报告为主，现已成为世界自然科学研究领域最著名的期刊之一，除此之 外，Cell出版社目前还陆续发行了十几种姊妹刊，在各自专业领域里均占据着举足轻重的地位。2011年8月，Cell出版社又推出了全新的开放获取期 刊：Cell Reports，这是自2007年Cell出版社新增Cell Stem Cell和Cell Host & Microbe两份期刊后的又一重要新成员。
Cell Reports致力于报道整个生命科学领域的高质量研究成果，主要集中于短小，单个观点的文章——当然也接受标准长度的论文，因此这一期刊命名为Reports。与所有Cell出版社期刊一样，这份期刊的审稿标准也是新的生物观点。
Cell出版社系列期刊的优势之一是对论文开放获取的支持，从2005年起，这一出版社就免费开放了1995年至最近12个月前的文献全文。作为 Cell出版社旗下的首个开放获取期刊，Cell Reports也秉承了这一承诺，而且还为作者提供了面向全球的快速可被获取捷径。
目前Cell Reports已开始接受投稿，发表费用为每篇5000美元，由作者支付，预计创刊将于2012年1月出版。
与此类似的是，今年Nature集团也宣布创办开发获取期刊：Scientific Reports，后者主要涉及的领域包括生物学，化学，物理学和地球科学。
在最新公布的2010最新SCI影响因子（journal citation reports）中，Cell出版社旗下的期刊影响因子得到了大幅增加，比如《Cell》本刊的影响因子达到了32.401，《Immunity》的影响 因子跃升为24.221，提高了18%，从而称为免疫学领域中影响因子最高的一份期刊。其次《Cancer Cell》的影响因子也增长了6.5%，达到26.925。而2007年Cell出版社新增的两份期刊：《Cell Stem Cell》影响因子则达到了25.943，提高了10%，《Cell Host & Microbe》达到了13.728。
（生物通：万纹）
26 January, 2012 Volume 1, Issue 1EditorialMore than the Sum of Its Parts p1More than the Sum of Its Parts
Boyana Konforti
Welcome to the first issue of Cell Reports, a new open-access journal that covers all of biology with a focus on high-quality short papers. There are, of course, other open-access journals—in fact, quite a number have launched just in recent years (and there will almost certainly be more to follow)—though few have the high standards and prestige of the Cell Press brand. There are also other journals that publish short papers, and still others that have a broad remit. But it is the unique combination of these features that will distinguish Cell Reports within Cell Press and beyond—think of the old adage of the sum being greater than its parts.
Cell Reports will place particular emphasis on shorter, single-point stories, called Reports. This focus comes from an awareness that science moves very fast and that there is a need for a high-profile, open-access place to publish intriguing, cutting-edge material that describes one or two key findings. These Reports are not meant for preliminary findings that are not well supported by the data. Instead, they should represent a significant advance in the field that will drive further research and perhaps even raise more questions than they answer. We will also publish the more typical comprehensive, longer-format papers that Cell Press journals are so famous for. The primary criterion for both these types of papers, as for all Cell Press journals, will be new biological insight. Cell Reports will also have a section for Resources, which describe significant technical advances and/or major informational data sets.
Open access means that readers will have immediate and unrestricted access to all papers published in Cell Reports. Authors will retain full copyright for their articles and can choose to publish their work in Cell Reports under one of two Creative Commons licenses. One option allows others to distribute, modify, and build upon the paper, both commercially and non-commercially, and is the most accommodating license that Creative Commons offers. The other option allows the article to be copied and distributed, but it cannot be changed in any way or used commercially.
The aim of Cell Reports will be to publish high-quality papers encompassing all scales of biology, from the organism to the atom. The broad scope of Cell Reports demands an actively engaged editorial board. To that end, we turned to our advisors, well-established senior scientists working across different areas of biology, to help us identify editorial board members who are up-and-coming new leaders in their respective scientific fields. This unique editorial board of dedicated and enthusiastic scientists will help shape the journal from the bottom up, with their expertise well grounded in the present but with their eyes on where science is headed in the future. In addition to the expertise of our editorial board, we work closely with and rely on the advice and experience of the in-house editors across all of the Cell Press journals. This allows Cell Reports to make fast initial review decisions, choose fair and knowledgeable reviewers, and make well-informed, decisive editorial judgments across a broad range of disciplines. As part of the Cell Press family, Cell Reports benefits from the manuscript-transfer system between journals, so one review process can serve for consideration at more than one journal. Cell Reports will publish accepted papers quickly, and new papers will go online every week. Finally, we will also be able to offer all the advantages of the Article of the Future format, including the graphical abstract and highlights as well as all the online Cell Press extras such as podcasts and videos.
The in-house editorial team of Cell Reports consists of me and Sabbi Lall. I've been a professional editor for over 13 years. Most recently, I was Chief Editor of Nature Structural & Molecular Biology. Before becoming an editor I did two postdocs—one at Columbia University with Anna Pyle, and the other at The Rockefeller University with Magda Konarska, studying RNA splicing. My PhD work was on DNA recombination at Stanford University with Ron Davis. I have also just completed a textbook with John Kuriyan and David Wemmer (both at UC Berkeley), called The Molecules of Life: Physical and Chemical Principles (Garland Science: New York), that will be published later this year. Sabbi comes to Cell Reports with both research and editorial experience under her belt. Her PhD work was done in the Ish-Horowicz lab (Oxford University), where she worked on genes involved in Drosophila segmentation. Her postdoctoral work with Fabio Piano and Nikolaus Rajewsky, both at New York University, examined and identified microRNA targets during C. elegans development. She has spent the last five years honing her editorial skills with me at Nature Structural & Molecular Biology. But as I said before, Sabbi and I do not work alone—we work closely with our editorial board, the other Cell Press editors, and of course our reviewers. Cell Reports not only depends on this collaboration, it thrives because of it.
In the first issue we have five Reports: one paper shows that mutations are not random, another gives us a glimpse of how protein translocation across membranes works, another describes an essential component of cholesterol accumulation, another argues that the Hippo signaling pathway predates the origin of metazoans, and another identifies the genetic basis of a movement disorder. One Research Article describes how alternative splicing produces distinct heat-sensing channels in flies, and the other shows how activation of one kind of inflammasome leads to aging of the thymus. Finally, there is a Resource paper that describes a global analysis of RNA secondary structure in two metazoans.
Does the first issue cover all of biology? In a word, no—it couldn't possibly. Nor will the second issue. But we hope that, in time, Cell Reports will publish the best in fields as far apart as ecology and synthetic biology or paleontology and biophysics. I want to thank the reviewers and especially the authors who have made Cell Reports possible. It takes an adventurous spirit to be part of a new journal (even one at Cell Press), and I thank the reviewers for holding the bar high and the authors for believing in our long-term success. And now we turn to the rest of you as readers, reviewers, and authors to fulfill our potential.
Premetazoan Origin of the Hippo Signaling Pathway p13
Structure of the SecY Complex Unlocked by a Preprotein Mimic p21
An Essential Role of Hrs/Vps27 in Endosomal Cholesterol Trafficking p29
Mutation Hot Spots in Yeast Caused by Long-Range Clustering of Homopolymeric Sequences p36
ArticlesThermosensory and Nonthermosensory Isoforms of Drosophila melanogaster TRPA1 Reveal Heat-Sensor Domains of a ThermoTRP Channel p43
The NLRP3 Inflammasome Promotes Age-Related Thymic Demise and Immunosenescence p56
ResourceGlobal Analysis of RNA Secondary Structure in Two Metazoans p69
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