在一项新的细胞研究中，伊利诺伊大学的研究人员已经修改CRISPR基因编辑技术，使细胞的内部机制在转录成蛋白质构建模板时跳过基因的一小部分。这给研究者提供了一种不仅可以消除突变的基因序列，而且可以影响基因的表达和调控的方法。这种有针对性的编辑可能有助于治疗基因组突变引起的遗传疾病，如杜氏肌营养不良症、亨廷顿氏病或一些癌症。

New CRISPR technology may help eliminate mutated gene sequence

New CRISPR technique skips over portions of genes that can cause...

phys.org/news/2018-08-crispr-technique-portions-genes-disease.html

New CRISPR technique skips over portions of genes that can cause...

www.sciencedaily.com/releases/2018/08/180816153147.htm

New CRISPR technique skips over portions of genes that can cause disease

https://www.sciencedaily.com/releases/2018/08/180816153147.htm

1. Michael Gapinske, Alan Luu, Jackson Winter, Wendy S. Woods, Kurt A. Kostan, Nikhil Shiva, Jun S. Song, Pablo Perez-Pinera. CRISPR-SKIP: programmable gene splicing with single base editors. Genome Biology, 2018; 19 (1) DOI: 10.1186/s13059-018-1482-5