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Crystal structures of adiponectin receptors released
热度 1 袁曙光 2015-4-17 21:12
Nature 520, 312–316 (16 April 2015) doi:10.1038/nature14301 Full text Abstract Adiponectin stimulation of its receptors, AdipoR1 and AdipoR2, increases the activities of 5′ AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptor (PPAR), respectively, thereby c ...
个人分类: 好文转载|2000 次阅读|2 个评论 热度 1
creating USB stick Windows/Linux installer under Linux
袁曙光 2015-3-5 15:20
Nowadays it is more and more popular to install an OS from usb stick because of it is faster than DVD disk and rewriterable. Here are some Linux tools for creating USB stick installer for Windows and Linux. (1)WINUSB: creating Windows usb installer from ISO image or real DVD download from ...
个人分类: Linux相关|2321 次阅读|没有评论
Schrodinger 2015-1 released
热度 2 袁曙光 2015-2-11 21:32
From http://www.schrodinger.com New features: Molecular Dynamics New mixed all-atom/coarse grain (AACG) capability (command line only) Enables more rapid simulation of proteins in water and membranes Protein-ligand pocket detection with AACG pocket_finde Maest ...
个人分类: Linux相关|3697 次阅读|3 个评论 热度 2
2014 FDA drug approvals
袁曙光 2015-2-9 18:32
From Nature Reviews Drug Discovery 14, 77–81(2015) doi:10.1038/nrd4545 Drug (brand name) Sponsor Properties Indications Review types Dapagliflozin (Farxiga) AstraZeneca SGLT2 inhibitor Type 2 diabetes S Tasimelteon (Hetlioz) Vanda Melatonin-receptor agonist ...
个人分类: 好文转载|3781 次阅读|没有评论
Generic GPCR residue numbering
袁曙光 2015-2-1 23:14
Trends in pharmacological science, Volume 36, Issue 1, p22–31, January 2015 Abstract Generic residue numbers facilitate comparisons of, for example, mutational effects, ligand interactions, and structural motifs. The numbering scheme by Ballesteros and Weinstein for residues within the cl ...
个人分类: 科研笔记|3732 次阅读|没有评论
Structure of Ca2+ ion channel solved at near atomic level
袁曙光 2014-12-22 04:54
Nature (2014) doi:10.1038/nature14063 Received 12 September 2014 Accepted 12 November 2014 Published online 15 December 2014 full text: http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14063.html The ryanodine receptors ...
个人分类: 科研笔记|1890 次阅读|没有评论
Harvard researchers find protein that could reverse aging
袁曙光 2014-12-21 03:05
From http://www.gizmag.com By Anthony Wood Researchers from the Harvard Stem Cell Institute (HSCI) have shown that injections of a protein dubbed GDF11, when administered to older mice, appear to cause a reversal of many signs of aging. Analysis showed that every major organ ...
个人分类: 科研笔记|2382 次阅读|没有评论
BioVersys works to bring antinbiotic resistance to an end
袁曙光 2014-12-18 23:43
From http://www.venturekick.ch 9 December 2014 - In May this year, BioVersys started a project in collaboration with Lille University and GlaxoSmithKline to develop a preclinical candidate for the treatment of tuberculosis, a disease that alone kills more than 1.5 million people each ...
个人分类: 好文转载|1944 次阅读|没有评论
Merry Christmas and Happy New Year
热度 1 袁曙光 2014-12-17 05:38
个人分类: 科研笔记|1793 次阅读|1 个评论 热度 1
best PDF editor under Linux
袁曙光 2014-12-11 22:05
Master PDF Editor, a conveient and smart XPS and PDF editor for Linux Master PDF Editor provides you advanced functions for working with PDF and XPS formats: • Create new PDF and XPS files or edit existing ones. • Add and/or edit bookmarks in PDF files. • F ...
个人分类: Linux相关|2605 次阅读|没有评论

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