All protein ligand interactions take place in bulk environment. It is important to predict how water molecules in the binding pocket affect their interactions. Thus, a number of tools, including WATsite , Waterdock , Schrodinger Watermap , OpenEYE SZMAP and WaterLap , were developed for this ...
Nature 520, 312–316 (16 April 2015) doi:10.1038/nature14301 Full text Abstract Adiponectin stimulation of its receptors, AdipoR1 and AdipoR2, increases the activities of 5′ AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptor (PPAR), respectively, thereby c ...
Nowadays it is more and more popular to install an OS from usb stick because of it is faster than DVD disk and rewriterable. Here are some Linux tools for creating USB stick installer for Windows and Linux. (1)WINUSB: creating Windows usb installer from ISO image or real DVD download from ...
From http://www.schrodinger.com New features: Molecular Dynamics New mixed all-atom/coarse grain (AACG) capability (command line only) Enables more rapid simulation of proteins in water and membranes Protein-ligand pocket detection with AACG pocket_finde Maest ...
Trends in pharmacological science, Volume 36, Issue 1, p22–31, January 2015 Abstract Generic residue numbers facilitate comparisons of, for example, mutational effects, ligand interactions, and structural motifs. The numbering scheme by Ballesteros and Weinstein for residues within the cl ...
Nature (2014) doi:10.1038/nature14063 Received 12 September 2014 Accepted 12 November 2014 Published online 15 December 2014 full text: http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14063.html The ryanodine receptors ...
From http://www.gizmag.com By Anthony Wood Researchers from the Harvard Stem Cell Institute (HSCI) have shown that injections of a protein dubbed GDF11, when administered to older mice, appear to cause a reversal of many signs of aging. Analysis showed that every major organ ...
From http://www.venturekick.ch 9 December 2014 - In May this year, BioVersys started a project in collaboration with Lille University and GlaxoSmithKline to develop a preclinical candidate for the treatment of tuberculosis, a disease that alone kills more than 1.5 million people each ...
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