科学网

 找回密码
  注册
搜索
热搜: 科学 论文
搜索
分享 Another class C GPCR structure released
袁曙光 2014-7-10 04:37
Structure of the human class C GPCR metabotropic glutamate receptor 5 transmembrane domain in complex with the negative allosteric modulator mavoglurant Nature (2014) doi:10.1038/nature13396 Received20 January 2014 Accepted22 April 2014 Published online06 July 2014 ...
个人分类: 科研笔记|1759 次阅读|没有评论
分享 [转载]China’s rise as a major contributor to Science & Technology
袁曙光 2014-7-5 02:23
From: China’s rise as a major contributor to Science and Technology PNAS | July 1, 2014 | vol. 111 | no. 26 | 9437–9442 In the past three decades, China has become a major contributor toscience and technology. China now employs an increasingly large labor force of scientists an ...
个人分类: 好文转载|2426 次阅读|没有评论
分享 Two MMPBSA calculation tools in Gromacs
袁曙光 2014-7-1 23:50
Molecular Mechanics- Poisson Bolzmann Surface Area (MMPBSA) is a versatile method to calculate the binding free energies of a protein/ligand complex. It incorporates the effects of thermal averaging with a force field/continuum solvent model to post-process a series of representative snapshots fr ...
个人分类: 科研笔记|8936 次阅读|没有评论
分享 install NVIDIA Optimus for laptop
袁曙光 2014-5-23 03:28
Nowadays, it is quite common and popular to have two dedicated graphic cards in laptop: usually, one is intergrated (eg: intel HD4xxx ) and the other is indepedent (eg: Nvidia GTX xxx). Such strategy can save laptop energy if we use integrated card for document task; while we can switch to inde ...
个人分类: Linux相关|5265 次阅读|没有评论
分享 convert multimedia between different formats
袁曙光 2014-5-5 04:00
Converting multimedia between different formats can be needed for different purposes. Although there are many tools under Windows, it is still feasible for such task under Linux OS including both command line and GUI end tool. Here are some popular methods for such purposes: ...
个人分类: Linux相关|2203 次阅读|没有评论
分享 Hazards Of Functional Groups
袁曙光 2014-4-18 03:12
Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. Most of the time in drug discovery are spend in optimizing compound properties including absorption, distribution, metabolism, and excretion (ADME). The four criteria all influence ...
个人分类: 科研笔记|3045 次阅读|没有评论
分享 Class C GPCR structure released
袁曙光 2014-3-17 20:45
Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator Science DOI: 10.1126/science.1249489 Abstract he excitatory neurotransmitter glutamate induces modulatory actions via the metabotropic glutamate receptors (mGlus), which &n ...
1943 次阅读|没有评论
分享 PyMOL v1.7.0.0 Release Notes
袁曙光 2014-2-4 23:33
Release Date: January 14, 2014. Graphics new labels visual additions : connectors, backgrounds, and outlines Note: We are building an interface that will make it easier to control labels interactively so that you won’t need to remember all of these settings explicitly, but th ...
个人分类: 科研笔记|2452 次阅读|没有评论
分享 FDA Approves 27 New Drugs in 2013
袁曙光 2014-2-1 17:12
The new drug approvals for 2013 were mostly cancer drugs and drugs for orphan diseases. Other therapeutic areas included metabolic and endocrinological therapies (two type 2 diabetes drugs and one dyslipidaemia drug), antivirals (two hepatitis C virus (HCV) drugs and an HIV drug) and medical ima ...
个人分类: 好文转载|2621 次阅读|没有评论
分享 Linux Kernel 3.13 released
袁曙光 2014-1-21 04:09
From : http://kernelnewbies.org/ Linux 3.13 Linux 3.13 was released on Sun, 19 Jan 2014. Summary : This release includes nftables, the successor of iptables, a revamp of the block layer designed for high-performance SSDs, a power capping framework to cap power consumption ...
个人分类: Linux相关|3288 次阅读|没有评论

Archiver|手机版|科学网 ( 京ICP备14006957 )

GMT+8, 2019-7-23 00:23

Powered by ScienceNet.cn

Copyright © 2007- 中国科学报社

返回顶部