提出问题：Cells continuously move through these zones; thus, a major question is how the boundary between these domains, the transition zone, is formed and maintained. 

主要发现：By combining molecular genetics with computational modeling, we reveal how an auxin/PLETHORA/ARR-B network controls these dynamic patterning processes. 

结果：We show that after germination, cell division causes a drop in distal PLT2 levels that enables transition zone formation and ARR12 activation. The resulting PLT2-ARR12 antagonism controls expansion of the division zone (the meristem). The successive ARR1 activation antagonizes PLT2 through inducing the cell-cycle repressor KRP2, thus setting final meristem size. 

结论：Our work indicates a key role for the interplay between cell division dynamics and regulatory networks in root zonation and transition zone patterning.

拟南芥种子一旦萌发后，细胞分裂会产生PLT水平下降，从而形成过渡区

A PLTs-ARR12 mutual antagonism restricts early root meristem expansion

PLTs与ARR12之间的相互拮抗，限制了根分生组织的早期扩张

ARR1 repression of cell division via KRP2 is key for meristem size stabilization

ARR1通过KRP2抑制细胞分裂对于保持分生组织大小稳定十分重要

Auxin-PLTs-ARRs form a network responsible for self-organized root patterning

Auxin-PLTs-ARRs形成了一个网络，作用于自组织的根模式建成