痤疮是毛囊皮脂腺单位的一种慢性炎症性皮肤病，主要好发于青少年，对青少年的心理和社交影响很大，但青春期后往往能自然减轻或痊愈。临床表现以好发于面部的粉刺、丘疹、脓疱、结节等多形性皮损为特点。http://baike.baidu.com/link?url=qt0NA79pfPGnwYwnzi0eahKRsnTJw0M-8Ehh4ebZnKKmYnoBtfN6KHiCZwi4fcpoPV37T_l9LuIjQ7atkq_EaK

李竞 青春痘的前世今生http://blog.sciencenet.cn/blog-825582-928237.html

      我采用知识发现的方法，对青春痘与焦虑和抑郁的关系进行了分析，发现相关的问题很多（118个密切相关问题），科研人员在选题研究时可以参考。

A-query: Pimple OR Acne Vulgaris
C-query: anxiety and depression

The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 74 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here. The results of this search are saved under id # 13702 and can be accessed from the start page after you leave this session. There are 328 terms on the current B-list (118 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin.

To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.

http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi

job id # 13702 started Wed Oct 14 20:40:19 2015
Max_citations: 50000
Stoplist: /var/www/arrowsmith_uic/data/stopwords_pubmed
Ngram_max: 3
A_query_raw: Pimple Wed Oct 14 20:40:24 2015

A query = Pimple started Wed Oct 14 20:40:25 2015
A query resulted in 99 titles
C_query_raw: depression Wed Oct 14 20:41:27 2015

C: depression 335092

A: Pimple 99

AC: ( Pimple ) AND ( depression ) 5

C_query_raw: depression Wed Oct 14 20:41:30 2015

C: depression 335092

A: Pimple 99

AC: ( Pimple ) AND ( depression ) 5

C query = depression started Wed Oct 14 20:41:30 2015
C query resulted in 50000 titles
A AND C query resulted in 5 titles
626 B-terms ready on Wed Oct 14 20:41:42 2015

Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
58 B-terms left after filter executed Wed Oct 14 20:42:11 2015

Viewed B-terms Wed Oct 14 20:42:33 2015
hiv

C_query_raw: isotretinoin Wed Oct 14 20:45:30 2015

C: isotretinoin 3788

A: Pimple 99

AC: ( Pimple ) AND ( isotretinoin ) 1

C_query_raw: isotretinoin Wed Oct 14 20:45:35 2015

C: isotretinoin 3788

A: Pimple 99

AC: ( Pimple ) AND ( isotretinoin ) 1

C query = isotretinoin started Wed Oct 14 20:45:35 2015
C query resulted in 3788 titles
A AND C query resulted in 1 titles
355 B-terms ready on Wed Oct 14 20:45:37 2015

Viewed B-terms Wed Oct 14 20:46:26 2015
hpv

A_query_raw: Pimple OR Acne Vulgaris Wed Oct 14 20:47:23 2015

A query = Pimple OR Acne Vulgaris started Wed Oct 14 20:47:24 2015
A query resulted in 10652 titles
C_query_raw: anxiety and depression Wed Oct 14 20:48:07 2015

C: anxiety and depression 67956

A: Pimple OR Acne Vulgaris 10652

AC: ( Pimple OR Acne Vulgaris ) AND ( anxiety and depression ) 74

C_query_raw: anxiety and depression Wed Oct 14 20:48:11 2015

C: anxiety and depression 67956

A: Pimple OR Acne Vulgaris 10652

AC: ( Pimple OR Acne Vulgaris ) AND ( anxiety and depression ) 74

C query = anxiety and depression started Wed Oct 14 20:48:11 2015
C query resulted in 50000 titles
A AND C query resulted in 74 titles
10645 B-terms ready on Wed Oct 14 20:48:36 2015

Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
540 B-terms left after filter executed Wed Oct 14 20:49:09 2015

Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
1 B-terms left after filter executed Wed Oct 14 20:49:44 2015

Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
1 B-terms left after filter executed Wed Oct 14 20:49:56 2015

Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
540 B-terms left after filter executed Wed Oct 14 20:50:31 2015

Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
540 B-terms left after filter executed Wed Oct 14 20:50:45 2015

C_query_raw: anxiety and depression Wed Oct 14 20:51:20 2015

C: anxiety and depression 67956

A: Pimple OR Acne Vulgaris 10652

AC: ( Pimple OR Acne Vulgaris ) AND ( anxiety and depression ) 74

C query = anxiety and depression started Wed Oct 14 20:51:21 2015
C query resulted in 50000 titles
A AND C query resulted in 74 titles
10645 B-terms ready on Wed Oct 14 20:51:44 2015

Sem_filter:
Disorders
1342 B-terms left after filter executed Wed Oct 14 20:52:33 2015

Sem_filter:
Concepts & Ideas
Phenomena
328 B-terms left after filter executed Wed Oct 14 20:53:06 2015

B-list on Wed Oct 14 20:55:42 2015
1 depression suicidal ideation
2 antiretroviral therapy
3 depression suicidal behavior
4 psychogenic excoriation
5 qol
6 association depression
7 chronic skin disease
8 treatment depressed
9 ovarian syndrome
10 risk breast cancer
11 health related
12 incidence depression
13 effect oral contraceptive
14 body image
15 initiation antiretroviral therapy
16 controlled parallel
17 blind clinical
18 self injury
19 blind placebo controlled
20 life depressive
21 insulin sensitivity
22 depression suicide risk
23 disorder primary
24 polycystic
25 randomised double blind
26 stress biomarker
27 double blind trial
28 risk prostate cancer
29 australian general
30 aesthetic
31 parallel group
32 breast cancer risk
33 blind controlled
34 double blind clinical
35 depressive
36 double blind placebo
37 venous thromboembolism
38 chronic skin disorder
39 social impairment
40 insulin therapy
41 stage renal disease
42 stress induced myocardial
43 serum lipid
44 single blind
45 remission
46 beta thalassemia major
47 therapy inflammatory bowel
48 aesthetic rhinoplasty
49 double blind
50 premenstrual syndrome frequency
51 quality life depressive
52 depression patient
53 blind comparison
54 therapy women
55 syndrome depression
56 t polymorphism
57 rural urban
58 sun exposure
59 double blind randomised
60 therapy polycystic ovary
61 therapy levodopa
62 activity daily living
63 cancer mortality
64 hyperplasia 21-hydroxylase deficiency
65 novel mutation
66 treatment alzheimer disease
67 relationship acne
68 based therapy
69 arthritis musculoskeletal
70 abdominal obesity
71 study depressive
72 cause depression
73 acid serum lipid
74 necrosis factor alpha
75 treatment obesity
76 diagnosis polycystic ovary
77 therapy severe
78 rehabilitation patient
79 depression new
80 depression
81 depression related
82 health problem
83 advanced breast cancer
84 esthetic
85 advanced cancer
86 treatment migraine
87 adjunctive therapy
88 related health
89 treatment multiple sclerosis
90 decrease insulin sensitivity
91 unemployment
92 rehabilitation
93 treatment endometriosis
94 infected human immunodeficiency
95 tuberous sclerosis complex
96 diabetes cardiovascular
97 depression not
98 therapy treatment
99 high protein low
100 therapy patient
101 treatment psoriasis
102 signaling pathogenesis
103 therapy adolescent
104 post mi
105 pubertal maturation
106 history
107 radiotherapy breast cancer
108 negative social
109 relationship stress
110 pregnant
111 women systemic lupus
112 treatment aggression
113 therapy chronic hepatitis
114 depression associated
115 depression case
116 disorder young
117 benign malignant breast
118 mosaic

http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/view_b_txt.cgi?ID=13702