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他汀类药物国际研究文献分析报告 1970 - 2019年

已有 752 次阅读 2019-6-21 13:40 |个人分类:信息分析|系统分类:科研笔记




他汀类药物是毒药 

http://blog.sciencenet.cn/home.php?mod=space&uid=280034&do=blog&id=1185858

共有49064条符合本次的查询结果.

年份年份趋势图

记录数

占%

 01.2019     644 1.813%

 02.2018     1077 3.032%

 03.2017     1618 4.555%

 04.2016     2178 6.131%

 05.2015     2534 7.133%

 06.2014     2696 7.589%

 07.2013     2479 6.978%

 08.2012     2363 6.652%

 09.2011     2402 6.762%

 10.2010     2369 6.669%

 11.2019     644 1.813%

 12.2017     1618 4.555%

 13.2007     2117 5.959%

 14.2006     1955 5.503%

 15.2005     1843 5.188%

 16.2004     1580 4.448%

 17.2003     1357 3.820%

 18.2002     1059 2.981%

 19.2001     888 2.500%

 20.2000     550 1.548%

 21.1999     429 1.208%

 22.1998     364 1.025%

 23.1997     233 0.656%

 24.1996     202 0.569%

 25.1995     204 0.574%

 26.1994     163 0.459%

 27.1993     140 0.394%

 28.1992     118 0.332%

 29.1991     119 0.335%

 30.1990     109 0.307%

 31.1989     78 0.220%

 32.1988     63 0.177%

 33.1987     46 0.129%

 34.1986     36 0.101%

 35.1985     36 0.101%

 36.1984     30 0.084%

 37.1983     26 0.073%

 38.1982     26 0.073%

 39.1981     33 0.093%

 40.1980     24 0.068%

 41.1979     11 0.031%

 42.1978     17 0.048%

 43.1977     14 0.039%

 44.1976     11 0.031%

 45.1975     6 0.017%

 46.1974     1 0.003%

 47.1972     1 0.003%

 48.1970     1 0.003%

期刊期刊分区中科院期刊分区

记录数

占%

 01.am j cardiol     927 2.610%

 02.atherosclerosis     694 1.954%

 03.circulation     472 1.329%

 04.j am coll cardiol     449 1.264%

 05.int j cardiol     388 1.092%

 06.lancet     339 0.954%

 07.plos one     322 0.906%

 08.bmj     308 0.867%

 09.jama     278 0.783%

 10.curr atheroscler rep     267 0.752%

 11.eur heart j     238 0.670%

 12.n engl j med     238 0.670%

 13.am heart j     225 0.633%

 14.arterioscler thromb vasc biol     224 0.631%

 15.curr med res opin     193 0.543%

 16.stroke     191 0.538%

 17.j clin lipidol     186 0.524%

 18.am j med     183 0.515%

 19.ann intern med     172 0.484%

 20.j atheroscler thromb     167 0.470%

 21.j biol chem     159 0.448%

 22.curr opin lipidol     155 0.436%

 23.cardiovasc drugs ther     154 0.434%

 24.j cardiovasc pharmacol     153 0.431%

 25.biochem biophys res commun     151 0.425%

 26.circ j     150 0.422%

 27.clin ther     150 0.422%

 28.curr pharm des     145 0.408%

 29.clin cardiol     144 0.405%

 30.nihon rinsho     142 0.400%

 31.curr vasc pharmacol     139 0.391%

 32.eur j clin pharmacol     139 0.391%

 33.arch intern med     133 0.374%

 34.int j clin pract     131 0.369%

 35.j lipid res     131 0.369%

 36.expert opin pharmacother     128 0.360%

 37.ann pharmacother     126 0.355%

 38.mmw fortschr med     122 0.343%

 39.am j cardiovasc drugs     121 0.341%

 40.eur j pharmacol     120 0.338%

 41.can j cardiol     119 0.335%

 42.heart     119 0.335%

 43.br j clin pharmacol     118 0.332%

 44.clin pharmacol ther     117 0.329%

 45.biochim biophys acta     115 0.324%

 46.pharmacotherapy     113 0.318%

 47.neurology     111 0.312%

 48.pharmacoepidemiol drug saf     106 0.298%

 49.j vasc surg     105 0.296%

 50.angiology     102 0.287%

国家国家分布图

记录数

占%

 01.美国     8699 24.488%

 02.英国     2200 6.193%

 03.日本     1988 5.596%

 04.意大利     1474 4.149%

 05.中国大陆     1449 4.079%

 06.德国     1438 4.048%

 07.加拿大     1173 3.302%

 08.荷兰     956 2.691%

 09.法国     938 2.640%

 10.西班牙     781 2.199%

 11.澳大利亚     676 1.903%

 12.瑞典     503 1.416%

 13.希腊     490 1.379%

 14.韩国     478 1.346%

 15.波兰     417 1.174%

 16.印度     411 1.157%

 17.瑞士     406 1.143%

 18.中国台湾     384 1.081%

 19.巴西     383 1.078%

 20.土耳其     334 0.940%

 21.芬兰     285 0.802%

 22.以色列     252 0.709%

 23.挪威     245 0.690%

 24.丹麦     239 0.673%

 25.奥地利     216 0.608%

 26.比利时     209 0.588%

 27.捷克共和国     204 0.574%

 28.伊朗     191 0.538%

 29.新西兰     154 0.434%

 30.匈牙利     129 0.363%

 31.中国香港     112 0.315%

 32.爱尔兰     104 0.293%

 33.俄罗斯     101 0.284%

 34.南非     90 0.253%

 35.葡萄牙     84 0.236%

 36.新加坡     73 0.205%

 37.阿根廷     73 0.205%

 38.罗马尼亚     69 0.194%

 39.墨西哥     68 0.191%

 40.沙特阿拉伯     66 0.186%

 41.埃及     58 0.163%

 42.斯洛文尼亚     56 0.158%

 43.泰国     56 0.158%

 44.马来西亚     51 0.144%

 45.斯洛伐克     49 0.138%

 46.智利     48 0.135%

 47.巴基斯坦     28 0.079%

 48.黎巴嫩     26 0.073%

 49.卡塔尔     19 0.053%

 50.冰岛     16 0.045%

大陆城市境外城市

记录数

占%

 01.美国波士顿     878 2.472%

 02.英国伦敦     753 2.120%

 03.美国纽约     603 1.697%

 04.日本东京     461 1.298%

 05.美国芝加哥     356 1.002%

 06.美国休斯敦     344 0.968%

 07.美国洛杉矶     314 0.884%

 08.法国巴黎     297 0.836%

 09.加拿大多伦多     290 0.816%

 10.意大利米兰     284 0.799%

查看更多

大陆作者作者与主题词全部作者作者邮件

记录数

占%

 01.Mikhailidis DP     275 0.774%

 02.Kastelein JJ     201 0.566%

 03.Ridker PM     140 0.394%

 04.Athyros VG     139 0.391%

 05.Ballantyne CM     130 0.366%

 06.Wang Y     123 0.346%

 07.Davidson MH     120 0.338%

 08.Zhang Y     113 0.318%

 09.Mascitelli L     108 0.304%

 10.Watts GF     107 0.301%

 11.Li Y     106 0.298%

 12.Cannon CP     101 0.284%

 13.Banach M     100 0.281%

 14.Gotto AM     100 0.281%

 15.Rosenson RS     98 0.276%

 16.Jukema JW     97 0.273%

 17.Aronow WS     94 0.265%

 18.Karagiannis A     94 0.265%

 19.Wierzbicki AS     94 0.265%

 20.Goldstein MR     93 0.262%

 21.Laufs U     91 0.256%

 22.Shepherd J     90 0.253%

 23.Thompson PD     90 0.253%

 24.Nicholls SJ     86 0.242%

 25.Saito Y     85 0.239%

 26.Li J     83 0.234%

 27.Blumenthal RS     82 0.231%

 28.Elisaf MS     79 0.222%

 29.Liu Y     79 0.222%

 30.Catapano AL     77 0.217%

 31.Liu J     77 0.217%

 32.Pezzetta F     76 0.214%

 33.Li X     75 0.211%

 34.Li L     73 0.205%

 35.Pedersen TR     73 0.205%

 36.Stein EA     73 0.205%

 37.Toth PP     73 0.205%

 38.Tousoulis D     73 0.205%

 39.Zhang J     73 0.205%

 40.Olsson AG     72 0.203%

 41.Wang J     72 0.203%

 42.Liao JK     69 0.194%

 43.Sattar N     69 0.194%

 44.Wang X     69 0.194%

 45.Ray KK     68 0.191%

 46.Robinson JG     68 0.191%

 47.Tziomalos K     68 0.191%

 48.Jacobson TA     67 0.189%

 49.Böhm M     66 0.186%

 50.Chen Y     65 0.183%

大陆机构第一作者机构合著机构境外机构

记录数

占%

 01.哈佛医学院     596 1.678%

 02.布莱根妇女医院     392 1.103%

 03.加州大学     349 0.982%

 04.德克萨斯大学     271 0.763%

 05.贝勒医学院     214 0.602%

 06.华盛顿大学     208 0.586%

 07.法国国家健康医学研究院     190 0.535%

 08.美国加州大学洛杉矶分校     179 0.504%

 09.约翰霍普金斯大学     176 0.495%

 10.瑞典卡罗琳斯卡医学院     169 0.476%

 11.米兰大学     162 0.456%

 12.美国克里夫兰诊所     151 0.425%

 13.密歇根大学     148 0.417%

 14.布鲁斯堡大学     146 0.411%

 15.多伦多大学     140 0.394%

 16.美国德州大学西南医学中心     135 0.380%

 17.美国密西根大学     132 0.372%

 18.埃默里大学     130 0.366%

 19.皇家学院     129 0.363%

 20.美国梅奥诊所     129 0.363%

 21.西澳大学     129 0.363%

 22.伦敦帝国理工学院     128 0.360%

 23.密歇根大学安娜堡分校     128 0.360%

 24.赫尔辛基大学     127 0.358%

 25.哥伦比亚大学     123 0.346%

 26.杜克大学     123 0.346%

 27.德克萨斯大学西南医学中心     122 0.343%

 28.杜克大学医院     122 0.343%

 29.hippokration医院     120 0.338%

 30.美国西北大学     116 0.327%

 31.北卡罗来纳大学     115 0.324%

 32.伦敦大学学院     114 0.321%

 33.麻省总医院     112 0.315%

 34.威尔康乃尔医学院     111 0.312%

 35.va医学中心     110 0.310%

 36.奥斯陆大学     109 0.307%

 37.宾夕法尼亚大学     108 0.304%

 38.牛津大学     107 0.301%

 39.加州大学洛杉矶分校医学院     106 0.298%

 40.麦吉尔大学     106 0.298%

 41.卡罗林斯卡大学附属医院     102 0.287%

 42.斯坦福大学     102 0.287%

 43.杜克大学医学中心     102 0.287%

 44.英属哥伦比亚大学     102 0.287%

 45.东京大学     101 0.284%

 46.艾奥尼纳大学     99 0.279%

 47.雅典大学     98 0.276%

 48.埃默里大学医学院     97 0.273%

 49.荷兰莱顿大学     94 0.265%

 50.科罗拉多大学     91 0.256%

主题词主题词搭配主题词与主题词

记录数

占%

 01.hydroxymethylglutaryl-coa reductase inhibitors     23414 65.910%

 02.risk factors     4642 13.067%

 03.anticholesteremic agents     4197 11.815%

 04.treatment outcome     4081 11.488%

 05.simvastatin     3952 11.125%

 06.cardiovascular diseases     3917 11.026%

 07.cholesterol, ldl     3888 10.945%

 08.hypercholesterolemia     3358 9.453%

 09.heptanoic acids     3353 9.439%

 10.pyrroles     3311 9.320%

 11.cholesterol     3252 9.154%

 12.hypolipidemic agents     2332 6.565%

 13.coronary disease     2091 5.886%

 14.pravastatin     1940 5.461%

 15.time factors     1875 5.278%

 16.drug therapy, combination     1859 5.233%

 17.lovastatin     1844 5.191%

 18.hyperlipidemias     1805 5.081%

 19.coronary artery disease     1788 5.033%

 20.dose-response relationship, drug     1748 4.921%

 21.randomized controlled trials as topic     1618 4.555%

 22.myocardial infarction     1598 4.498%

 23.cholesterol, hdl     1530 4.307%

 24.retrospective studies     1529 4.304%

 25.risk assessment     1523 4.287%

 26.lipids     1500 4.222%

 27.sulfonamides     1449 4.079%

 28.prospective studies     1431 4.028%

 29.pyrimidines     1422 4.003%

 30.clinical trials as topic     1409 3.966%

 31.dyslipidemias     1408 3.964%

 32.fluorobenzenes     1393 3.921%

 33.triglycerides     1360 3.828%

 34.follow-up studies     1353 3.809%

 35.atherosclerosis     1292 3.637%

 36.cells, cultured     1258 3.541%

 37.double-blind method     1230 3.462%

 38.stroke     1227 3.454%

 39.endothelium, vascular     1217 3.426%

 40.diabetes mellitus, type 2     1216 3.423%

 41.c-reactive protein     1157 3.257%

 42.practice guidelines as topic     1145 3.223%

 43.angiotensin-converting enzyme inhibitors     1078 3.035%

 44.biological markers     1007 2.835%

 45.platelet aggregation inhibitors     1004 2.826%

 46.hypertension     995 2.801%

 47.drug interactions     994 2.798%

 48.indoles     988 2.781%

 49.hydroxymethylglutaryl coa reductases     963 2.711%

 50.cohort studies     944 2.657%

Substance化学药中药

记录数

占%

 01.hydroxymethylglutaryl-coa reductase inhibitors     23414 65.910%

 02.anticholesteremic agents     4197 11.815%

 03.simvastatin     3952 11.125%

 04.cholesterol, ldl     3888 10.945%

 05.heptanoic acids     3353 9.439%

 06.pyrroles     3311 9.320%

 07.cholesterol     3252 9.154%

 08.atorvastatin     3029 8.527%

 09.hypolipidemic agents     2332 6.565%

 10.pravastatin     1940 5.461%

查看更多

疾病症状治疗方法物种解剖食品

记录数

占%

 01.心血管疾病     15383 43.303%

 02.营养与代谢疾病     10206 28.730%

 03.血管疾病     10125 28.502%

 04.代谢疾病     8759 24.657%

 05.心脏病     8061 22.692%

 06.血脂异常     7899 22.236%

 07.脂类代谢紊乱     6951 19.567%

 08.高脂血症     6243 17.574%

 09.心肌缺血     5727 16.122%

 10.冠状动脉疾病     4998 14.069%

 11.冠状动脉病变     4905 13.808%

 12.高胆固醇血症     4780 13.456%

 13.糖尿病     4442 12.504%

 14.动脉粥样硬化     4223 11.888%

 15.动脉闭塞性疾病     3710 10.444%

 16.动脉硬化     3575 10.064%

 17.神经系统疾病     3553 10.002%

 18.心肌梗塞     3027 8.521%

 19.肿瘤     2810 7.910%

 20.中风     2599 7.316%

 21.中枢神经系统疾病     2508 7.060%

 22.内分泌系统疾病     2485 6.995%

 23.脑疾病     2455 6.911%

 24.葡萄糖代谢障碍     2378 6.694%

 25.高血压     2336 6.576%

 26.脑血管障碍     1840 5.180%

 27.肾疾病     1775 4.997%

 28.男性泌尿生殖器疾病     1679 4.726%

 29.创伤和损伤     1666 4.690%

 30.2型糖尿病     1648 4.639%

 31.肌骨骼疾病     1617 4.552%

 32.女性泌尿生殖器疾病和妊娠并发症     1587 4.467%

 33.肌疾病     1585 4.462%

 34.女性泌尿生殖器疾病     1510 4.251%

 35.泌尿系疾病     1413 3.978%

 36.脑梗塞     1236 3.479%

 37.疼痛     1217 3.426%

 38.急性冠脉综合征     1178 3.316%

 39.心力衰竭     1122 3.158%

 40.肾功能不全     1073 3.020%

 41.免疫系统疾病     1050 2.956%

 42.胰岛素抵抗     1029 2.897%

 43.消化系统疾病     979 2.756%

 44.动物疾病模型     969 2.728%

 45.先天性遗传性新生儿疾病和畸形     940 2.646%

 46.先天性遗传性疾病     923 2.598%

 47.肥胖症     901 2.536%

 48.横纹肌溶解     900 2.533%

 49.高脂蛋白血症ii型     859 2.418%

 50.感染     857 2.412%

科室学科

记录数

占%

 01.department of medicine     2329 6.556%

 02.department of internal medicine     1428 4.020%

 03.department of cardiology     1345 3.786%

 04.division of cardiology     915 2.576%

 05.school of medicine     692 1.948%

 06.department of neurology     626 1.762%

 07.department of pharmacology     509 1.433%

 08.department of cardiovascular medicine     324 0.912%

 09.college of medicine     291 0.819%

 10.department of surgery     286 0.805%

 11.school of pharmacy     277 0.780%

 12.college of pharmacy     217 0.611%

 13.department of epidemiology     216 0.608%

 14.division of cardiovascular medicine     213 0.600%

 15.department of biochemistry     199 0.560%

 16.department of pharmacy     196 0.552%

 17.department of pediatrics     186 0.524%

 18.division of nephrology     182 0.512%

 19.department of nephrology     165 0.464%

 20.department of pathology     164 0.462%

 21.department of urology     148 0.417%

 22.department of clinical pharmacology     144 0.405%

 23.academic medical center     143 0.403%

 24.school of public health     142 0.400%

 25.department of physiology     140 0.394%

 26.division of endocrinology     139 0.391%

 27.department of vascular medicine     137 0.386%

 28.department of neurosurgery     126 0.355%

 29.department of radiology     117 0.329%

 30.department of anesthesiology     115 0.324%

 31.department of obstetrics and gynecology     114 0.321%

 32.department of endocrinology     113 0.318%

 33.department of clinical biochemistry     111 0.312%

 34.duke university medical center     108 0.304%

 35.leiden university medical center     105 0.296%

 36.university of texas southwestern medical center     97 0.273%

 37.department of family medicine     90 0.253%

 38.department of pharmacy practice     89 0.251%

 39.school of medicine and pharmacology     89 0.251%

 40.department of vascular surgery     88 0.248%

 41.division of endocrinology and metabolism     86 0.242%

 42.university medical center utrecht     82 0.231%

 43.center for cardiovascular disease prevention     80 0.225%

 44.department of biostatistics     80 0.225%

 45.department of laboratory medicine     80 0.225%

 46.department of public health     79 0.222%

 47.department of ophthalmology     76 0.214%

 48.department of chemistry     72 0.203%

 49.department of dermatology     72 0.203%

 50.department of psychiatry     71 0.200%




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