许培扬博客分享 http://blog.sciencenet.cn/u/xupeiyang 跟踪国际前沿 服务国内科研

博文

屠呦呦 糖尿病人的福音

已有 2025 次阅读 2016-12-4 09:13 |个人分类:诺贝尔奖|系统分类:观点评述



屠呦呦团队的青蒿素或可治糖尿病

资料图:屠呦呦。资料图:屠呦呦。

  由我国药学家屠呦呦和她的团队研制出的青蒿素药物至今仍然是世界范围内最主要的抗疟药物,成功挽救了数百万人的生命。

  12月1日,在线发表于美国Cell(《细胞》)杂志上的一项突破性研究表明,这一药物或许还可以拯救数亿糖尿病患者。来自奥地利科学院CeMM分子医学研究中心等机构的科学家,利用一种特别设计的、全自动化的分析,科学家们检测了大量已批准药物对人工培养的α细胞的作用。结果惊喜地发现,青蒿素能够让产生胰高血糖素的α细胞“变身”产生胰岛素的β细胞。

http://news.sina.com.cn/c/nd/2016-12-04/doc-ifxyiayq2229106.shtml


Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

Jin Li, Tamara Casteels, Thomas Frogne, Camilla Ingvorsen, Christian Honoré, Monica Courtney, Kilian V.M. Huber, Nicole Schmitner, Robin A. Kimmel, Roman A. Romanov, Caterina Sturtzel, Charles-Hugues Lardeau, Johanna Klughammer, Matthias Farlik, Sara Sdelci, Andhira Vieira, Fabio Avolio, François Briand, Igor Baburin, Peter Májek, Florian M. Pauler, Thomas Penz, Alexey Stukalov, Manuela Gridling, Katja Parapatics, Charlotte Barbieux, Ekaterine Berishvili, Andreas Spittler, Jacques Colinge, Keiryn L. Bennett, Steffen Hering, Thierry Sulpice, Christoph Bock, Martin Distel, Tibor Harkany, Dirk Meyer, Giulio Superti-Furga, Patrick Collombat, Jacob Hecksher-Sørensen, Stefan Kubicek
Published online: December 1, 2016

Open Access

http://www.cell.com/cell/newarticles

Cell
CountryUnited States
616
H Index
Subject Area and CategoryBiochemistry, Genetics and Molecular Biology
Biochemistry, Genetics and Molecular Biology (miscellaneous)
PublisherCell Press
Publication typeJournals
ISSN00928674, 10974172
Coverage1974-ongoing
ScopeFor more than 30 years, top international researchers have relied on Cell to publish high impact papers that have come to form the foundation of contemporary life science research. Founded by Benjamin Lewin (author of Genes), Cell remains at the forefront of exciting developments in biology, continually redefining the important areas of science with cutting edge papers. Published biweekly, Cell includes original research articles of exceptional significance in areas including molecular biology, biochemistry, cancer research, cell biology, developmental biology, genetics, immunology, microbiology, neurobiology, plant biology, structural biology and virology. (source)

http://www.scimagojr.com/journalsearch.php?q=18434&tip=sid&clean=0




http://blog.sciencenet.cn/blog-280034-1018560.html

上一篇:韩春雨落选长江学者奖励计划
下一篇:精准医疗 治好癌症 目的明确

2 尚成英 nuobeier1997

该博文允许注册用户评论 请点击登录 评论 (4 个评论)

数据加载中...

Archiver|手机版|科学网 ( 京ICP备14006957 )

GMT+8, 2020-1-24 09:22

Powered by ScienceNet.cn

Copyright © 2007- 中国科学报社

返回顶部