路漫漫其修远兮分享 http://blog.sciencenet.cn/u/zhpd55 追求科学,勇于探索,苦海无涯,愿作小舟。

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国际技术、健康卫生与化学新闻提要 (1月27日)

已有 6397 次阅读 2015-1-28 17:48 |个人分类:新科技|系统分类:博客资讯| 化学, 技术, 国际新闻, 健康卫生

国际技术、健康卫生与化学新闻提要 (127日)

诸平

已经有几天没有摘转国际技术、健康卫生与化学新闻提要了,原因是近日上火牙痛啊,真正领教了什么是“牙痛不是病,痛起来要人命。”所以,连着几天去医院找医生,今天下午算是处理了以下,实际上也可以说是昨天治疗的继续,从医院冒雪(小雪,地上可以看到积雪了。前几次下雪,地上根本没有积雪)回来,看到了27日的新闻,摘转如下。要逐条翻译成中文,可能看到后就已经不是新闻(News)了,而且由于自己水平所限,就是翻译也未必能够做到忠实原意,所以,还是原样摘录如下,喜欢者自己品味吧。

Nanotechnology news

Quantum dots combined with antibodies as a method for studying cells in their native environment

(Phys.org)—To understand cell function, we need to be able to study them in their native environment, in vivo. While there are many techniques for studying cells in vitro, or in the laboratory setting, in vivo studies are much more difficult. A new study by a team of researchers at the Massachusetts Institute of Technology and Harvard Medical School used a unique quantum dot-antibody conjugate to facilitate in vivo studies of bone marrow stem cells in mice. This study was reported in the Proceedings of the National Academy of Science.

'Bulletproof' battery: Kevlar membrane for safer, thinner lithium rechargeables

New battery technology from the University of Michigan should be able to prevent the kind of fires that grounded Boeing 787 Dreamliners in 2013.

Stomach acid-powered micromotors get their first test in a living animal

Researchers at the University of California, San Diego have shown that a micromotor fueled by stomach acid can take a bubble-powered ride inside a mouse. These tiny motors, each about one-fifth the width of a human hair, may someday offer a safer and more efficient way to deliver drugs or diagnose tumors.

Researchers tune friction in ionic solids at the nanoscale

Friction impacts motion, hence the need to control friction forces. Currently, this is accomplished by mechanistic means or lubrication, but experiments conducted by researchers at the Department of Energy's Oak Ridge National Laboratory have uncovered a way of controlling friction on ionic surfaces at the nanoscale using electrical stimulation and ambient water vapor.

Carbon nanoballs can greatly contribute to sustainable energy supply

Researchers at Chalmers University of Technology have discovered that the insulation plastic used in high-voltage cables can withstand a 26 per cent higher voltage if nanometer-sized carbon balls are added. This could result in enormous efficiency gains in the power grids of the future, which are needed to achieve a sustainable energy system.

Nanoparticles that deliver oligonucleotide drugs into cells described

Therapeutic oligonucleotide analogs represent a new and promising family of drugs that act on nucleic acid targets such as RNA or DNA; however, their effectiveness has been limited due to difficulty crossing the cell membrane. A new delivery approach based on cell-penetrating peptide nanoparticles can efficiently transport charge-neutral oligonucleotide analogs into cells, as reported in Nucleic Acid Therapeutics.

Technology news

High-end 'upstream' Linux laptop plans to ship in April

A unique laptop wastes no time in promoting its worth in its title, the Purism Librem 15. Its team maintain that this is "the first high-end laptop in the world that ships without mystery software in the kernel, operating system, or any software applications." The laptop carries appeal for those who are frustrated over paying for a machine with an OS carrying "suspect proprietary software," without the user knowing what that software does. The company says the value of going free/libre and open source is for an important reason: "unless every aspect of your kernel, operating system, and software applications are free/libre and open source, there is no way to know that your computer is truly working in your best interest."

Twitter woos users with group chat and video features

Twitter on Tuesday began rolling out new group chat and video features as it worked to ramp up use of the one-to-many messaging service.

Facebook: Internal glitch caused hour-long global outage (Update)

Facebook said it suffered a self-inflicted outage lasting an hour on Tuesday that made its site inaccessible to users worldwide.

New search engine lets users look for relevant results faster

Researchers at the Helsinki Institute for Information Technology HIIT have developed a new search engine that outperforms current ones, and helps people to do searches more efficiently.

Obama sees need to move on drone rules now (Update)

President Barack Obama says the wayward quadcopter that crashed on the White House grounds—flown by an off-duty intelligence employee—shows that the U.S. must take steps to ensure commercial and consumer drones are used safely.

Computerised vehicles are vulnerable to hacking and theft

Theft of vehicles is about as old as the notion of transport – from horse thieves to carjackers. No longer merely putting a brick through a window, vehicle thieves have continually adapted to new technology, as demonstrated by a new method to steal a car without the need to be anywhere near it.

New gadgets and gimmicks to keep us watching sport live on TV

Australia's love of sport appears to be more from in front of a TV screen than actually attending any event live, and that could be on the increase given some of the new technology heading our way.

Research applications of unmanned aerial vehicles

Mississippi State University researchers are preparing for the day when unmanned aerial vehicles, commonly known as drones, can be used commercially in agriculture.

Pilotless aircraft will play critical roles in precision agriculture

Comparing an unmanned aerial vehicle to a magnetic resonance imaging machine may seem odd, but that is how the director of the Mississippi State University Geosystems Research Institute sees it.

Transmitting wireless data on higher frequencies

Everything we do that requires a wireless connection uses the radio spectrum. We're able to harness radio waves to listen to music in the car or stream Netflix from the 4G network on our smartphones. Each application is assigned its own frequency within the spectrum. The problem is that space is limited and our demand is only increasing. But what if we weren't bound by this crowded spectrum?

Messaging app hides pictures in plain site on Facebook

Snoop-thwarting messaging application Wickr on Tuesday began letting Apple mobile gadget users hide pictures in plain site on their Facebook pages.

Using 3-D printing, MakerBot and Feinstein Institute repair tracheal damage

Investigators at The Feinstein Institute for Medical Research have made a medical breakthrough using 3D printing on a MakerBot Replicator 2X Experimental 3D Printer to create cartilage designed for tracheal repair or replacement. The results were reported today at the 51st Annual Meeting of The Society of Thoracic Surgeons in San Diego, in a presentation by Todd Goldstein, an investigator at the Feinstein Institute, part of the North Shore-LIJ Health System. This is a first for medical research where regular MakerBot PLA Filament was used to 3D print a custom tracheal scaffolding, which was combined with living cells to create a tracheal segment.

Tech sector hot, but no bubble: analyst study

Dealmaking in the tech sector jumped last year to the highest levels since the dot-com boom, a consultancy report said Tuesday.

NREL reports examine economic trade-offs of owning versus leasing a solar photovoltaic system

Two new reports from the Energy Department's National Renewable Energy Laboratory (NREL) examine the economic options customers face when deciding how to finance commercial or residential solar energy systems. NREL analysts found that businesses that use low-cost financing to purchase a photovoltaic (PV) system and homeowners who use solar-specific loans can save up to 30 percent compared with consumers who lease a PV system through a conventional third-party owner.

What! Facebook's down? No storm selfies during brief outage

No storm selfies, hookups, status updates. With Facebook and Instagram down for nearly an hour overnight, what were legions of users to do?

Snapchat to show content from big media brands

Popular disappearing-message app Snapchat is introducing content from media companies such as Vice, CNN and People to its service as it works to broaden its audience.

Microsoft tanks 10 percent, hit by four downgrades on earnings

Microsoft shares plunged more than 10 percent Tuesday after the software giant reported quarterly revenue that beat expectations but warned that a weak PC market and a strong dollar will curb growth this year. Many analysts slashed price targets on the stock and some cut their Buy ratings to Hold.

US watchdog urges safeguards for 'Internet of Things'

A US government consumer watchdog agency called Tuesday for better privacy and security to be built into the myriad of connected devices, for fitness, smart homes or other uses.

Google super-fast US Internet service spreads

Google's super-fast Internet service—up to 100 times quicker than basic broadband—is heading for four more US metropolitan areas as the technology titan ramps up pressure on cable service giants.

Yahoo announces tax-free spinoff of Alibaba stake

Yahoo announced plans Tuesday for a tax-free spinoff of its stake in Chinese Internet giant Alibaba, splitting off the valuable holdings from its core operations.

Big costs drag AT&T to 4Q loss, but revenue up 4 percent

AT&T booked a nearly $4 billion loss for the fourth quarter because of a slew of one-time expenses that included a loss on benefit plans, but its revenue grew 4 percent to top expectations.

Google wireless service could disrupt carriers

Internet users from San Jose to Kansas City have been clamoring for Google to lay down its long-awaited fiber-optic network to compete with Comcast and AT&T in speeding up Web and television access. Now the Silicon Valley search giant plans to do battle with the telecommunications industry on another front: wireless phone service.

Record iPhone sales drive blowout quarter for Apple

Apple had another blowout quarter thanks to its new plus-sized iPhones, which helped the company smash sales records for the holiday season.

Aircraft with a parallel hybrid engine tested in UK

More research is needed before commercial airliners will be powered entirely with electric motors but tests with hybrid designs are turning up interesting results. Researchers from the University of Cambridge in association with Boeing have tested an aircraft with a parallel hybrid engine in the UK, the first ever to be able to recharge its batteries in flight. The Cambridge report said that the test flights took place at the Sywell Aerodrome near Northampton. The tests involved hops along the runway and evaluation flights at a height over 1,500 feet.

Cubans look to US detente for better Web access

Alfredo Castellano travels half an hour to Havana twice a week to write emails in a computer center with a Fidel Castro poster outside and aging machines inside.

Mineral scarcity and environmental technologies seen as opportunities

As mineral resources are dwindling, it is becoming increasingly important to know how even the tiniest amounts of minerals can be recovered from waste - or how minerals can be substituted for other materials in industrial use. The VTT Mineral Economy innovation programme develops new technologies for, for instance, the mining industry.


NREL releases the 2013 Renewable Energy Data Book, detailing increases in installed capacity

The newly released 2013 Renewable Energy Data Book illustrates United States and global energy statistics, including renewable electricity generation, renewable energy development, clean energy investments, and technology-specific data and trends. The Data Book is produced and published annually by the National Renewable Energy Laboratory (NREL) on behalf of the Energy Department's Office of Energy Efficiency and Renewable Energy.

New study will help researchers change face of military training

The Office of Naval Research (ONR) this week launched a study that could lead to breakthroughs in creating the next-generation of avatars, robots and other human surrogates for military training.

Medicine & Health news

A challenge to expedite Genervon's new ASL drug

(Medical Xpress)—The Ice Bucket Challenge to raise awareness for Amyotrophic lateral sclerosis (ALS) went viral on social media last summer. Over 1.2 million videos were posted on Facebook alone. The difficulty in treating a disease like ALS is highlighted by the fact that the only drug available for it, Riluzole, extends life expectancy by just a couple months. A new challenge was just issued to the FDA to make another drug available to sufferers of ALS. Specifically, a petition on Change.org by Nicholas Grillo for access to Genervon's GM6 drug has just acheived a critical mass of over 100,000 signatures.

Researchers pinpoint two genes that trigger severest form of ovarian cancer

In the battle against ovarian cancer, UNC School of Medicine researchers have created the first mouse model of the worst form of the disease and found a potential route to better treatments and much-needed diagnostic screens.

Scientists find drug candidates can block cell-death pathway associated with Parkinson's

In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute (TSRI) have shown their drug candidates can target biological pathways involved in the destruction of brain cells in Parkinson's disease.

Concentrating on word sounds helps reading instruction and intervention

A neuroimaging study by a University at Buffalo psychologist suggests that phonics, a method of learning to read using knowledge of word sounds, shouldn't be overlooked in favor of a whole-language technique that focuses on visually memorizing word patterns, a finding that could help improve treatment and diagnosis of common reading disorders such as dyslexia.

Human stem cells could one day be regulated to replace aged, damaged, and missing tissues

When a salamander loses a tail, it grows a new one. What's the difference, MIT biologist Peter Reddien PhD '02 wondered, between a wound that severs a salamander's tail and one that severs a human spinal cord?

Using stem cells to grow new hair

In a new study from Sanford-Burnham Medical Research Institute (Sanford-Burnham), researchers have used human pluripotent stem cells to generate new hair. The study represents the first step toward the development of a cell-based treatment for people with hair loss. In the United States alone, more than 40 million men and 21 million women are affected by hair loss. The research was published online in PLOS One yesterday.

Research into brain control of liver lipid production could cause break in obesity, diabetes treatment

Ways of keeping the heart healthy has widened, with the discovery that the brain can help fight off hardening of the arteries.

Death rates from lung cancer will overtake those for breast cancer in 2015 among EU women

Death rates from lung cancer will exceed those for breast cancer for the first time among European women in 2015, according to the latest predictions published in the leading cancer journal Annals of Oncology today.

Smoking may increase risks for patients being treated for prostate cancer

Among patients with prostate cancer, those who smoke have increased risks of experiencing side effects from treatment and of developing future cancer recurrences, or even dying from prostate cancer. The findings, which are published in BJU International, suggest that smoking may negatively affect the health outcomes of patients with prostate cancer and may contribute to complications related to their care.

Generic form of nexium approved

(HealthDay)—The first generic version of the heartburn drug Nexium (esomeprazole) has been approved by the U.S. Food and Drug Administration.

Analysis rejects linkage between testosterone therapy and cardiovascular risk

Fears of a link between testosterone replacement therapy and cardiovascular risk are misplaced, according to a review published in this month's Mayo Clinic Proceedings. The therapy has come under widespread scrutiny in recent months, including by a federal Food and Drug Administration (FDA) panel convened last fall.

MRIs link impaired brain activity to inability to regulate emotions in autism

Tantrums, irritability, self-injury, depression, anxiety. These symptoms are associated with autism, but they're not considered core symptoms of the disorder. Researchers from the UNC School of Medicine are challenging this assertion. They have used functional MRI to show that - when it comes to the ability to regulate emotions - brain activity in autistic people is significantly different than brain activity in people without autism.

Measles outbreak that began at Disneyland grows to 87 cases

A measles outbreak that originated at Disneyland has grown to 87 cases.

Mexico City swaps squats for subway rides

There may be no such thing as a free lunch, but the overweight in Mexico City will be glad to hear there is such a thing as a free subway ride.

Age concern in largest ever study of heroin user deaths

Older users of opioids such as heroin are 27 times more likely to become a victim of homicide than the general population, a University of Manchester study of almost 200,000 users has found.

New algorithm will allow better heart surgery

A new technique to help surgeons find the exact location of heart defects could save lives, help them to treat patients more effectively and save health service cash.

Metabolic process of the liver implicated in the spread of colorectal cancer

Colorectal cancer is a cancer on the move: about 50 percent of patients with the disease see their cancer spread, typically to the liver. By identifying genes that become activated in cancer cells that successfully travel—metastasize—to the liver, researchers at Rockefeller have implicated metabolic processes within the liver as a possible means by which starving transient cancer cells can go on to form deadly new colonies. The researchers say their finding represents vulnerability in metastasizing cancer cells that could be exploited with new drugs.

How pornography influences and harms sexual behavior

A new article co-authored by a Virginia Commonwealth University professor suggests that pornography has become a primary source of sexual education, and has a tangible influence on the sex lives of young adults.

In a severe flu season, Virginia Tech researcher searches for better ways to prevent infections

Linsey Marr, a professor in the Charles E. Via Jr. Department of Civil and Environmental Engineering at Virginia Tech, is obsessed with flu transmission.

Autistic subjects' facial expressions don't always mirror emotions

New research by UT Dallas scientists suggests that individuals with autism spectrum disorder can have very expressive faces, but the emotions conveyed can sometimes seem overly intense and unusual.

Neuroscience researchers believe in quitting smoking gradually

Smoking is harmful in almost every respect. Cancer, stroke, and other cardiovascular diseases are just a small part of a well-documented portfolio of serious consequences of smoking. Nicotine is what makes smoking addictive, but new Danish research suggests that smoking initially increases brain activity. However, the brain tissue quickly adapts and the effect will disappear. On the other hand, according to brain scans, the brain's oxygen uptake and blood flow decreases by up to 17% immediately after people stop smoking:

Researchers find hormone that increases the sex drive of mice

Researchers at the University of Gothenburg show that mice that receive a supplement of the "appetite hormone" ghrelin increase their sexual activity. Whether the hormone has the same impact on humans is unknown, but if it does, the researchers may have found the key to future treatments for sex abuse.

Inhibiting CDK6 prevents leukemic relapse

Despite enormous progress in cancer therapy, many patients still relapse because their treatment addresses the symptoms of the disease rather than the cause, the so-called stem cells. Work in the group of Veronika Sexl at the University of Veterinary Medicine, Vienna has given a tantalizing clue to a solution. In the current issue of Blood, the scientists report that the cell-cycle kinase CDK6 is required for activation of the stem cells responsible for causing leukemia.

Inherited gene variation helps explain drug toxicity in patients of East Asian ancestry

About 10 percent of young leukemia patients of East Asian ancestry inherit a gene variation that is associated with reduced tolerance of a drug that is indispensable for curing acute lymphoblastic leukemia (ALL), the most common childhood cancer. St. Jude Children's Research Hospital scientists led the study, which is being published online today in the Journal of Clinical Oncology.

Tips to enjoy a lifestyle that can prevent premature aging

New Year's has become synonymous with a desire to change your lifestyle – in fact, 4 in 10 individuals have been said to made resolutions to lose weight. But what about individuals who are facing physical limitations to weight loss and other barriers to healthy living?

Targeted MRI / ultrasound beats standard biopsy to detect high-risk prostate cancer

Targeted biopsy using new fusion technology that combines magnetic resonance imaging (MRI) with ultrasound is more effective than standard biopsy in detecting high-risk prostate cancer, according to a large-scale study published today in JAMA. More than 1,000 men participated in the research at the National Institutes of Health (NIH) over a seven-year period.

Brain region vulnerable to aging is larger in those with longevity gene variant

People who carry a variant of a gene that is associated with longevity also have larger volumes in a front part of the brain involved in planning and decision-making, according to researchers at UC San Francisco.

Why counting calories is not all about the numbers

Looking to stay healthy this year? A new regulation may help in your endeavor.

Survey indicates willingness of general population to donate tissue samples to biobank

A survey of nearly 1,600 individuals found that the majority were willing to donate tissue samples and medical information to a biobank for research and that most were willing to donate using a blanket consent, according to a study in the January 27 issue of JAMA.

Negative patient-doctor communication could worsen symptoms

Doctors who unintentionally communicate to patients that they do not believe or understand them could actually make their symptoms worse, a new study suggests.

Intracranial stimulation proved efficient in the recovery of learning and memory in rats

Stimulation of the hypothalamus completely reverses learning and memory deficits caused by brain lesions in rats, according to a first time discovery by a group of researchers led by the UAB. The research has also served to study the mechanisms through which this recovery occurs, suggesting that the stimulation of the hypothalamus activates several regions of the brain, especially the memory systems, which offer compensatory effects.

Discrimination is bad for your health – and your kids too

Think about the last time you left the house. Did strangers on the street acknowledge your presence with a smile or avert their glance? Chances are that the answer depended on your age, gender and, of course, your race.

Appraisal of stressful or threatening situations by the brain

Researchers at the Research Center Translational Neurosciences of Johannes Gutenberg University Mainz (JGU) in Germany have advanced a generalized concept as the basis for future studies of mental resilience. Their new approach is based on a mechanistic theory which takes as its starting point the appraisals made by the brain in response to exposure to stressful or threatening situations. Previously social, psychological, and genetic factors were in the foreground of resilience research. The Mainz-based team has published its conclusions in the renowned journal Behavioral and Brain Sciences.

Researchers find potential anti-cancer use for anti-epilepsy drug

Scientists at the University of York have discovered that a drug used widely to combat epilepsy has the potential to reduce the growth and spread of breast cancer.

Study finds traumatic brain injury treatment is ineffective

More than 1.7 million people in the U.S. alone suffer a traumatic brain injury (TBI) every year, often resulting in permanent disabilities or death. Up to half of these patients will experience progression of bleeding inside or around the brain, the occurrence of which is associated with an increased risk of death.

Study shows salivary biomarkers predict oral feeding readiness in preterm newborns

Results from a study published online in the Journal of Pediatrics hold the potential to substantially improve clinical decision-making to determine when a premature newborn is ready for oral feeding. The study describes developmental salivary biomarkers associated with feeding success in newborns, markers that could lead to development of objective assessment tools for caregivers.

Researchers gain new insights into hypothyroidism

An international research team led by physician-scientists at Rush University Medical Center has gained new insights into hypothyroidism - a condition affecting about 10 million people in the U.S. - that may lead to new treatment protocols for the disease, particularly among the approximately 15 percent of patients for whom standard treatments are less effective.

Association between parental time pressure and mental health problems among children

A doctor's thesis at Sahlgrenska Academy has found that children whose parents experience time pressure are more likely to have mental health problems.

Web surfing to weigh up bariatric surgery options

Obese people considering weight-reducing bariatric surgery are only topped by pregnant women when it comes to how often they turn to the Internet for health advice. While most use it to read up on relevant procedures and experiences, one in every four patients actually chooses a surgeon based solely on what he or she has gleaned from, in particular, websites hosted by public hospitals and former patients. This is according to a study in Springer's journal Obesity Surgery, led by Luca Paolino of the Joseph Ducuing Hospital in Toulouse, France.

Prostate cancer: Androgen receptor activates different genes when bound to antiandrogens

The androgen receptor in prostate cancer cells can activate different sets of genes depending on whether it binds with an androgen hormone or an antiandrogen drug, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James).

Beneficial effects of surgery for epilepsy are sustained for more than 15 years

Brain surgery for otherwise hard-to-treat epilepsy is effective for up to 15 years, according to a new survey by Henry Ford Hospital physicians.

Drug combo suppresses growth of late-stage prostate cancer tumors

Low doses of metformin, a widely used diabetes medication, and a gene inhibitor known as BI2536 can successfully halt the growth of late-stage prostate cancer tumors, a Purdue University study finds.

Lung cancer clues found in downstream pathway

Despite the promise of the gene KRAS as a target for treating lung cancer, finding effective therapies has been challenging. Now researchers are traveling down the pathway to find what makes KRAS cancerous.

Infant failure to thrive linked to lysosome dysfunction

Neonatal intestinal disorders that prevent infants from getting the nutrients they need may be caused by defects in the lysosomal system that occur before weaning, according to a new Northwestern Medicine study.

Man trumps dog: Earlier assumption about BPA exposure confirmed

Coating the mouth with BPA-containing food, like soup, does not lead to higher than expected levels of BPA in blood, a new study in Toxicology and Applied Pharmacology shows. The study authors conclude that oral exposure does not create a risk for high exposures.

Low-frequency deep brain stimulation improves difficult-to-treat Parkinson's symptoms (Update)

Parkinson's disease patients treated with low-frequency deep brain stimulation show significant improvements in swallowing dysfunction and freezing of gait over typical high-frequency treatment. The study, published in Neurology on Jan 27, provides a new route for treating Parkinson's patients with these difficult-to-treat and sometimes life-threatening symptoms.

Low influenza vaccination rates among nursing home employees put residents at risk, study finds

Influenza is associated with as many as 7,300 deaths annually in nursing home residents, but the vaccination rate for nursing home staff is only 54 percent, according to a study in the February issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

Surgeon general: 'Desperate need of clarity' on e-cigarettes

Public health officials are "in desperate need of clarity" on electronic cigarettes to help guide policies, the nation's newly appointed surgeon general said Tuesday.

Obama administration on track to surpass health care goal

Some 9.5 million people have already signed up for 2015 coverage under President Barack Obama's health care law, and the administration is on track to surpass its nationwide enrollment target set last year.

A son's struggles and triumphs after premature birth

(HealthDay)—Elise Jackson remembers very clearly the day her son was born: It was May 8, 2002, and Elijah had arrived 15 weeks before his due date.

Student loans take emotional toll on young adults

(HealthDay)—Student loan debt is a major cause of stress for young adults, a new study finds.

Blood transfusions during heart surgery may up pneumonia risk

(HealthDay)—Receiving a blood transfusion during heart bypass surgery may raise a patient's risk of pneumonia, researchers report.

Don't become a blizzard casualty

(HealthDay)—The blizzard conditions and frigid cold blanketing the U.S. Northeast pose numerous health threats, a doctor warns.

Provider demographics affect pain treatment decisions

(HealthDay)—Pain management treatment decisions may be impacted by a health care provider's demographic characteristics, according to a study published in the January issue of Pain Medicine.

How does DPP-4 inhibition affect liver function?

(HealthDay)—Dipeptidyl peptidase-4 (DPP-4) inhibition may attenuate hepatic steatosis and insulin resistance induced by the Western diet (WD) through hepatic lipid remodeling and modulation of hepatic mitochondrial function, according to research published online Jan. 20 in Diabetes.

Impact of intensive lifestyle change on CV burden studied

(HealthDay)—Intensive lifestyle modifications, the cornerstones of atherosclerotic disease management, are associated with a decrease in coronary and carotid atherosclerotic burden, according to a review published in the Jan. 15 issue of The American Journal of Cardiology.

Financial incentives help pregnant women to quit smoking

Pregnant women are more likely to quit smoking if financial rewards are offered as part of a treatment plan, finds new research published in The BMJ.

Cell mechanism discovered that may cause pancreatic cancer

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have found that defects in how cells are squeezed out of overcrowded tissue to die, a process called extrusion, may be a mechanism by which pancreatic cancer begins. From these findings, they may have identified an effective way to reverse the defective extrusion's effects without destroying normal tissues nearby. The results were published in the latest edition of the journal eLife.

Researchers advance the science behind treating patients with corneal blindness

Researchers in the Cedars-Sinai Board of Governors Regenerative Medicine Institute have devised a novel way to generate transplantable corneal stem cells that may eventually benefit patients suffering from life-altering forms of blindness.

World Bank: world 'dangerously unprepared' for pandemics

World Bank President Jim Yong Kim warned Tuesday that the world remains "dangerously unprepared" for deadly pandemics like the Ebola outbreak that has killed thousands in West Africa.

Decisions on future childbearing in women diagnosed with a meningioma

The diagnosis of a brain tumor—even one that's usually "benign" and slow growing such as a meningioma—can be scary. Meningiomas can cause temporary and permanent side effects and sometimes may recur even after surgical removal. In addition, a small percentage of primary or recurrent meningiomas are malignant. Imagine yourself a female meningioma survivor in your childbearing years. Some reports indicate that pregnancy may be a risk factor for tumor progression or recurrence. What do you do?

Uganda sued in landmark medical 'brain drain' case

Raymond Mwesiga's "darling kid sister" had much to live for, but when she needed medical help after a car crash, Uganda's overstretched health system fatally failed her.

Swiss drug maker Novartis posts Q4 profit drop

Swiss pharmaceutical giant Novartis AG says fourth quarter net income dropped 26 percent but the company still posted a healthy 2014 annual profit.

Obama to seek more funds for antibiotic-resistant bacteria fight

President Barack Obama will request a doubling of funds for fighting and preventing antibiotic-resistant bacteria in his 2016 budget, the White House said Tuesday.

Donors pledge $7.5 bn to extend child vaccine drive

Countries and private donors have pledged $7.5 billion (6.6 billion euros) to help immunise 300 million more children in developing countries over the next five years, a major vaccine alliance announced Tuesday.

Liberia closes Ebola centre at epicentre of outbreak

Liberia's president on Monday announced the closure of an Ebola treatment facility which lay at the epicentre of the virus's worst outbreak in history, as the disease's spread has slowed in the country.

Online monitoring system for patients with sleep apnoea

The company Medco Health at the Business, Scientific and Technological Park, Espaitec, of the Universitat Jaume I of Castellón, has developed a telemedicine assistance system that allows online daily monitoring of people with sleep apnoea-hypopnoea syndrome. The method proposed by the company is particularly focused on patient adherence to treatment as only 30% of patients successfully adapt to it.

Device for guided surgery of deviations in long bones

CEU-UCH Cardenal Herrera University patented a device for surgeries to correct deviations in long bones. The research team used the 3D simulation of an affected bone to determine the mathematical formula that for designing such a device, which is adjusted to a specific deviated bone and enables a surgeon to set the best cutting angle and the location and orientation of holes that accept the future addition of a corrective prosthesis. While realigning the affected limb, it also increases precision, shortens the time required for the operation, and improves the operation's functional results. The device has already been used with success in operations on animals and could have applications in orthopedic surgery on humans.

Ongoing dietary challenges for people with coeliac disease

University of Otago researchers have completed the first national survey of people with coeliac disease in New Zealand and found that many experience ongoing health challenges despite adhering to treatments.

Achieving a world without AIDS: Scale must give way to focus, details

The global AIDS community has its sights set on three new goals, known as the "90-90-90" targets. That is, by 2020, 90 percent of people living with HIV should know their HIV status, 90 percent of those who test positive for HIV should begin antiretroviral therapy (ART), and of those who begin ART, 90 percent should achieve virologic suppression, meaning their virus levels are not detectable using standard tests. Meeting these targets would be an enormous step toward a world without AIDS. However, to meet these targets, the traditional approach of broad, population-based treatments, prevention messages, and technologies must give way to more specific and focused approaches, according to a new commentary from Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and colleague Hilary D. Marston, M.D., M.P.H.

Novel radioguided brain surgery technique could help pinpoint cancerous tissue

A novel radioguided surgery technique could quickly and effectively identify residual cancer cells during brain tumor surgery, with low radiation exposure for both patients and surgeons. The study, featured in the January 2015 issue of the Journal of Nuclear Medicine, reports that Y-90 DOTATOC, a beta-minus-emitting tracer, can effectively delineate the margins of meningiomas and high-grade gliomas.

Use sterile or boiled water for nasal washing abroad to avoid amoeba infection

The Norwegian Institute of Public Health has been informed that a woman from Oslo died in December 2014 after returning from Thailand where she had been infected with the Naegleria fowleri amoeba. The source of infection appears to be daily nasal washing with tap water. If you are unsure about the water quality, always use sterile or boiled water for nasal washing, particularly in subtropical and tropical areas.

Pfizer net down on lower sales, higher research, legal costs

Pfizer Inc.'s fourth-quarter profit fell by half as worsening generic competition and unfavorable currency rates reduced sales, and higher research and legal costs also reduced the bottom line.

Low sodium levels increases liver transplant survival benefit in the sickest patients

Researchers report that low levels of sodium in the blood, known as hyponatremia, increase the risk of dying for patients on the liver transplant waiting list. The study published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, showed an increase in survival benefit for patients with hyponatremia and a Model for End Stage Liver Disease (MELD) score of 12 or more.

Amgen tops Street 4Q forecasts

Amgen Inc. cruised to a 27 percent jump in fourth-quarter profit and beat Wall Street expectations, due to higher sales of nearly all its medicines, tight cost controls and a tax benefit.

Funding for pulmonary rehabilitation study in East Africa

Chronic lung disease is a growing and debilitating health issue for countries in East Africa. Resulting from respiratory infections such as TB and HIV, and lifestyle problems such as tobacco smoking and poor nutrition, chronic lung disease affects one in five adults in Africa and is a major threat to health.

Women diagnosed with PCOS twice as likely to be hospitalized

Women diagnosed with polycystic ovary syndrome - the most common hormone disorder in women of reproductive age - face a heightened risk of developing heart disease, diabetes, mental health conditions, reproductive disorders and cancer of the lining of the uterus than healthy women, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

Indiana wins federal OK for state-run Medicaid alternative

Indiana has received federal approval to expand health coverage to about 350,000 uninsured residents through a state-run program Gov. Mike Pence said Tuesday will help the state's working poor families.

Chemistry news

Chemists use high speed camera to fully explain high school explosion demonstration

(Phys.org)—A team of researchers with members from Czech Republic and Germany has found that the general explanation given to high school chemistry students regarding the reasons for an explosion when alkali metals are dropped into water, is insufficient. In their paper published in the journal Nature Chemistry, the group explains how they filmed such reactions and discovered what really happens.

Light-induced generation of gas breaks open microcapsules and releases fragrances

Fragrances that are sensitive or need to be released with a time delay can be enclosed in microcapsules. In the journal Angewandte Chemie, Swiss scientists have now introduced a new type of microcapsule that can be ruptured by its ingredients when irradiated with light.

Micropore labyrinths as crucibles of life

Water-filled micropores in hot rock may have acted as the nurseries in which life on Earth began. An LMU team has now shown that temperature gradients in pore systems promote the cyclical replication and emergence of nucleic acids.

Design and enantioselective synthesis of new Cashmeran odorants

When a perfume is said to include Cashmere Wood, it means the typical smell of the odorant Cashmeran. As described in the journal Angewandte Chemie, scientists from Switzerland and Germany have introduced new members in this exclusive and precious family of scents, by using a novel synthetic strategy to synthesize enantiomerically pure products. Olfactory analysis of these compounds provided insight into the structural requirements for Cashmeran odorants.




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