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意大利生物学家蒙塔尔奇尼逝世103岁科学贡献与学术影响

已有 7364 次阅读 2012-12-31 09:37 |个人分类:科学名人|系统分类:人物纪事| 生物, 意大利, 影响力

http://www.guardian.co.uk/world/2012/dec/30/rita-levi-montalcini-biologist-dies

http://news.sciencenet.cn/htmlnews/2012/12/273469.shtm

丽塔·列维·蒙塔尔奇尼(1909-2012)，1909年4月22日出生于意大利的都灵，意大利神经生物学家，是当今最年长在世的诺贝尔奖得主，因发现神经生长因子以及上皮细胞生长因子而与斯坦利科恩共同获得1986年诺贝尔生理学或医学奖。

意大利著名女生物学家蒙塔尔奇尼逝世，享年103岁。蒙塔尔奇尼致力于研究人体细胞，她是一名犹太人，在纳粹占领期间，仍继续在地下实验室进行研究。1986年，她与美国科学家科恩共同获得诺贝尔医学奖。蒙塔尔奇尼一生从未结婚，亲属称在去世前她一直保持每天工作数小时。

http://baike.baidu.com/view/9167108.htm

http://beckerexhibits.wustl.edu/mig/bios/levi-montalcini.html

找到的结果数:	86

被引频次总计:	7351
去除自引的被引频次总计:	7122

施引文献:	5556
去除自引的施引文献:	5499

每项平均引用次数:	85.48

h-index :	37

http://apps.webofknowledge.com/CitationReport.do?product=UA&search_mode=CitationReport&SID=P1eAk@ombHmN54Bd@O@&page=1&cr_pqid=23&viewType=summary

Rita Levi-Montalcini

Consiglio Nazionale delle Ricerche

Publications: 32 | Citations: 1367 | G-Index: 32 | H-Index: 19

Interests: Neuroscience, Cell Biology, Molecular Biology

Collaborated with 66 co-authors from 1979 to 2012; Cited by 3349 authors

代表作

Nature 291, 413 - 415 (04 June 1981); doi:10.1038/291413a0

Somatic and behavioural postnatal effects of fetal injections of nerve growth factor antibodies in the rat

L. Aloe, C. Cozzari, P. Calissano & R. Levi-Montalcini

Laboratory of Cell Biology, CNR, Via Romagnosi 18/A, 00196 Rome, Italy

Previous work has shown that injections to neonatal mammals of a specific antiserum to the nerve growth factor (AS-NGF) produce irreversible destruction of sympathetic ganglia^1,2. The animals used in these studies were mice and rats. Because this treatment does not damage other nerve cells or produce adverse effects in other tissues and organs, the immunosympathectomized young and adult rodents do not exhibit—at gross inspection—somatic or behavioural differences compared with controls except for a marked ptosis³. Differences become apparent, however, when the treated rodents are submitted to physiological, pharmacological and behavioural tests⁴. We report here the dramatic effects that are produced by injections of purified antibodies to NGF in rat fetuses. A preliminary account of this work has already been presented^5,6, and similar effects have been demonstrated in another laboratory.

References

1.	Levi-Montalcini, R. & Booder, B. Proc. natn. Acad. Sci. U.S.A. 42, 384−391 (1960).
2.	Cohen, S. Proc. natn. Acad. Sci. U.S.A. 46, 302−311 (1960). \| ChemPort \|
3.	Levi-Montalcini, R. & Angeletti, P. U. Pharmac. Rev. 18, 619−628 (1966). \| ChemPort \|
4.	Steiner, G. & Schönbaum, E. Immunosympathectomy (Elsevier, Amsterdam, 1972).
5.	Levi-Montalcini, R. Nerve Cells, Transmitters and Behaviour, 84 (Elsevier, Amsterdam, 1980).
6.	Levi-Montalcini, R., Aloe, L., Calissano, P. & Cozzari, C. Abstr. 3rd Meet. int. Soc. dev. Neurosci., Strasbourg, 5−6 (1980).
7.	Bocchini, V. & Angeletti, P. U. Proc. natn. Acad. Sci. U.S.A. 64, 787−794 (1969). \| ChemPort \|
8.	Stoeckel, K., Gagnon, C., Guroff, G. & Thoenen, H. J. Neurochem. 26, 1207−1221 (1976). \| PubMed \| ISI \| ChemPort \|
9.	Cozzari, C., Angeletti, P. U., Lazar, J., Orth, H. & Cross, F. Biochem. Pharmac. 22, 1321−1327 (1973). \| Article \| ISI \| ChemPort \|
10.	Angeletti, P. U. & Levi-Montalcini, R. Proc. natn. Acad. Sci. U.S.A. 65, 114−121 (1970). \| ChemPort \|
11.	Angeletti, P. U. & Levi-Montalcini, R. Archs ital. Biol. 108, 213−221 (1970). \| ChemPort \|
12.	Levi-Montalcini, R., Aloe, L., Mugnaini, E., Oesch, F. & Thoenen, H. Proc. natn. Acad. Sci. U.S.A. 72, 595−599 (1975). \| ChemPort \|
13.	Aloe, L. & Levi-Montalcini, R. Proc. natn. Acad. Sci. U.S.A. 76, 1246−1250 (1979). \| ChemPort \|
14.	Levi-Montalcini, R. Harvey Lecture 60, 217−259 (1966). \| ChemPort \|
15.	Riley, C. M. & Moore, R. H. Pediatrics 37, 435−446 (1966). \| PubMed \| ISI \| ChemPort \|
16.	Pearson, J., Pytel, B. A., Grover-Johnson, N., Axerod, F. & Dancis, J. J. neurol. Sci. 35, 77−92 (1978). \| Article \| PubMed \| ISI \| ChemPort \|
17.	Dolkart Gorin, P. & Johnson, E. M. Proc. natn. Acad. Sci. U.S.A. 76, 5382−5386 (1979). \| ChemPort \|
18.	Schwartz, J. P. & Breakefield, X. O. Proc. natn. Acad. Sci. U.S.A. 77, 1154−1158 (1980). \| ChemPort \|
19.	Otten, U., Goedert, H., Mayer, N. & Lembeck, F. Nature 287, 158−159 (1980). \| PubMed \| ISI \| ChemPort \|
20.	Crain, S. M., Peterson, E. R., Leibam, M. & Schulman, H. Expl Neurol. 67, 205−214 (1980). \| Article \| ChemPort \|
21.	Freed, W. J. Brain Res. Bull. 1, 393−412 (1976). \| Article \| PubMed \| ISI \| ChemPort \|
22.	Benowitz, L. I. & Shashona, V. E. Brain Res. 172, 561−565 (1979). \| Article \| PubMed \| ISI \| ChemPort \|
23.	Walker, P., Weichsel, M. E., Fisher, D. A., Guo, S. M. & Fisher, D. A. Science 204, 127−129 (1979).
24.	Otten, U., Baumann, J. B. & Girard, J. Nature 282, 413−414 (1979). \| PubMed \| ISI \| ChemPort \|
25.	Gorin, P. D. & Johnson, E. M. Proc. natn. Acad. Sci. U.S.A. 76, 5382−5386 (1980).
26.	Johnson, E. M. et al. Science 210, 916−918 (1980). \| PubMed \| ISI \| ChemPort \|

http://www.nature.com/nature/journal/v291/n5814/abs/291413a0.html

代表作

THE NERVE GROWTH-FACTOR 35 YEARS LATER
作者: LEVIMONTALCINI, R (LEVIMONTALCINI, R)
来源出版物: SCIENCE 卷: 237 期: 4819 页: 1154-1162 DOI: 10.1126/science.3306916 出版年: SEP 4 1987
被引频次: 2,156 (来自 Web of Science)
引用的参考文献: 119 [ 查看 Related Records ] 引证关系图
入藏号: WOS:A1987J838900032
文献类型: Article
语种: English
通讯作者地址: LEVIMONTALCINI, R (通讯作者),NATL RES COUNCIL,INST CELL BIOL,ROME,ITALY.
出版商: AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005
Web of Science 类别: Multidisciplinary Sciences
研究方向: Science & Technology - Other Topics
IDS 号: J8389
ISSN: 0036-8075

THE NERVE GROWTH-FACTOR 35 YEARS LATER

作者: LEVIMONTALCINI, R (LEVIMONTALCINI, R)

来源出版物: SCIENCE 卷: 237 期: 4819 页: 1154-1162 DOI: 10.1126/science.3306916 出版年: SEP 4 1987

被引频次: 2,156 (来自 Web of Science)

引用的参考文献: 119 [ 查看 Related Records ]

引证关系图

入藏号: WOS:A1987J838900032

文献类型: Article

语种: English

通讯作者地址: LEVIMONTALCINI, R (通讯作者),NATL RES COUNCIL,INST CELL BIOL,ROME,ITALY.

出版商: AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005

Web of Science 类别: Multidisciplinary Sciences

研究方向: Science & Technology - Other Topics

IDS 号: J8389

ISSN: 0036-8075

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