...that the Natronobacterium gregoryi Argonaute (NgAgo) is a DNA-guided... ...genome editing in human cells. NgAgo binds 5′ phosphorylated single-... ...loaded with the gDNA. The NgAgo–gDNA system does not require...

Argonaute (NgAgo) with guide DNA (gDNA... ...for zebrafish. Recently the gDNA/NgAgosystem has elicited much interest... ...we investigated whether the gDNA/NgAgo system could be used to...

...and doubt that the protein, NgAgo, works as a gene...

(NgAgo) as a genome engineering... ...with a plasmid DNA encoding NgAgo and a 24-nucleotide,... ...gDNA sequences and used the NgAgo vector provided by Gao ...well as expression of the NgAgo protein. Despite various attempts... to optimize NgAgo-mediated genome editing in three...

...reported that an enzyme called NgAgo could be used to edit...

...Shijiazhuang, reported that the enzyme NgAgo can be used to edit...

...but the authors found that NgAgo, an Argonaute from ...25 nucleotides (nt). WhenNgAgo was expressed in human 293T... ...of off-target binding. Copurified NgAgo and ssDNA guides led to... . Unlike Cas9, NgAgo seemed to randomly remove 1...

(NgAgo). They found that,... ...when expressed in human cells, NgAgo did not associate with endogenous... ...the risk of guide swapping. NgAgo formed double-strand breaks (... ...repair with donor DNA. The NgAgo–gDNA system was at least...

(NgAgo) is a precise and... ...by the Cas9 nuclease — NgAgo can cleave targets using single... ...in length as a guide. NgAgo was found to create site... ...suggesting high fidelity of the NgAgo–gDNA system. Correct insertion...

...new gene-editing system called NgAgo

...of dollars in patent licences. NgAgo, a rival gene-editing...

...most recently DNA-guided endonuclease NgAgo, has considerably improved on-...