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Science—阻断丘脑腺苷A1R信号通路恢复成年小鼠听觉皮层可塑性

已有 2953 次阅读 2017-7-5 08:12 |个人分类:神经科学临床和基础|系统分类:观点评述

Science——阻断丘脑腺苷A1R信号通路恢复成年小鼠听觉皮层可塑性


1. Title、Authors、Summary

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1.Deletion of A1Rs in auditory thalamus is sufficient for passive tone exposure to induce auditory cortex map plasticity.

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2. Age-dependent increase of adenosine production underlies cortical map plasticity restrictions in adult mice.

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3. Restricting thalamic adenosine signaling or production is sufficient for passive tone exposure to cause a tuning shift in individual neurons in auditory cortex of awake mice.

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