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Science——阻断丘脑腺苷A1R信号通路恢复成年小鼠听觉皮层可塑性
1. Title、Authors、Summary
1.Deletion of A1Rs in auditory thalamus is sufficient for passive tone exposure to induce auditory cortex map plasticity.
2. Age-dependent increase of adenosine production underlies cortical map plasticity restrictions in adult mice.
3. Restricting thalamic adenosine signaling or production is sufficient for passive tone exposure to cause a tuning shift in individual neurons in auditory cortex of awake mice.
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