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Nature medicine——周细胞与脊髓损伤中毛细血管血流和运动功能损害相关
Abstract
1.Trace amines constrict capillaries at pericytes after SCI.
2.AADC, trace amines and 5-HT1B receptors are coexpressed in pericytes after SCI.
3.Poor blood flow and hypoxia after chronic SCI.
4.Treatments that dilate vessels and improve oxygenation after SCI lead to increased motor activity.
5.Thoracic contusion or staggered-hemisection injury induces chronic hypoxia that impairs locomotion.
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