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2019新型冠状病毒家庭成员(β属冠状病毒)研究概况

已有 7005 次阅读 2020-2-14 22:15 |个人分类:个人原创|系统分类:科普集锦


94cad1c8a786c9175889eec0c23d70cf3ac75744.jpg
冠状病毒(Coronavirus)是一个常见而又古老的病毒大家系,自发现以来一直被认为是对人类相对无害的一类病毒。2003年严重急性呼吸综合征冠状病毒(SARS-CoV)的暴发流行彻底颠覆了人类对于冠状病毒的已有认识,意识到其高致病潜能,并发现蝙蝠可以作为致命性冠状病毒的自然宿主。

随着分子技术的进步和人们对冠状病毒的深人研究和探索,分别于加04年和加05年发现人冠状病毒NL63(human Coronavirus NL63,HCoV-NL63)和人冠状病毒HKU1(Human Coronavirus HKU1,HCoV-HKU1)。2012年发生在阿拉伯半岛并持续进展的中东呼吸综合征冠状病毒(Middle East respiratory syndrome Coronavirus,MERS-CoV)的暴发流行,警示冠状病毒对人类仍存在重大危害,而其分布范围之广超乎人们的预期。HCoV-229E 和HCoV-NL63属于α属冠状病毒,COVID-19、HCoV-OC43、SARS-CoV、HCoV-HKU1 和MERS-CoV均为β属冠状病毒,其中,HCoV-OC43 和HCoV-HKU1 属于A亚群,SARS-CoV 属于B亚群,MERS-CoV属于C亚群。 2019新型冠状病毒(COVID-19)是目前已知的第7种可以感染人的冠状病毒,其余6种分别是HCoV-229E、HCoV-OC43、HCoV-NL63、HCoV-HKU1、SARS-CoV(引发重症急性呼吸综合征)  和MERS-CoV(引发中东呼吸综合征)。

其web of science中关于β属冠状病毒的研究概况如下:

概要:通过主题: (Betacoronavirus) OR 主题: (β-coronavirus)搜索显示有1,850 条相关研究记录,被引用45202次,平均每篇文献被引24.43次,引用频次相对较高。


出版物总数

1850分析

h-index97每项平均引用次数24.43

被引频次总计45202去除自引32312

施引文献

17488分析

去除自引

16075
分析

一、按年份的发表和被引频次


(一)每年发文论文数量:                                             (二)每年被引用情况:

image.pngimage.png

(三)被引用排名前十的文献基本信息
序号标题来源出版物名称出版年DOI及中文标题合计引用次数每年的平均数
1

Isolation   of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia


NEW   ENGLAND JOURNAL OF MEDICINE2012

10.1056/NEJMoa1211721

标题:

从沙特阿拉伯病人肺炎中分离出一种新型冠状病毒

1358150.89
2Severe   acute respiratory syndrome coronavirus-like virus in Chinese horseshoe batsPROCEEDINGS   OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA2005

10.1073/pnas.0506735102


标题:

中国菊头蝠中检测到高相似度的严重急性呼吸综合征冠状病毒

72045
3Food-borne   diseases - The challenges of 20 years ago still persist while new ones   continue to emergeINTERNATIONAL   JOURNAL OF FOOD MICROBIOLOGY2010

10.1016/j.ijfoodmicro.2010.01.021

标题:

食源性疾病(病从口入)——20年前的挑战依然存在:新型疾病不断出现

51446.73
4Middle   East respiratory syndrome coronavirus neutralising serum antibodies in   dromedary camels: a comparative serological studyLANCET   INFECTIOUS DISEASES2013

10.1016/S1473-3099(13)70164-6

标题:

血清学比较研究发现在单峰骆驼中存在中东呼吸综合征冠状病毒血清抗体

36645.75
5Genomic   Characterization of a Newly Discovered Coronavirus Associated with Acute   Respiratory Distress Syndrome in HumansMBIO2012

10.1128/mBio.00473-12

标题:

基因组学研究发现揭示在感染急性呼吸窘迫综合征(ARDS) 与一种新发现的冠状病毒关联

或:一种新发现的冠状病毒是导致人类急性呼吸窘迫综合征的罪魁祸首。


36640.67
6Discovery   of Seven Novel Mammalian and Avian Coronaviruses in the Genus   Deltacoronavirus Supports Bat Coronaviruses as the Gene Source of   Alphacoronavirus and Betacoronavirus and Avian Coronaviruses as the Gene   Source of Gammacoronavirus and DeltacoronavirusJOURNAL   OF VIROLOGY2012

10.1128/JVI.06540-11

标题:

研究发现蝙蝠携带7种哺乳动物易感染的α、β属冠状病毒和

新的哺乳动物和鸟类易感染的γ、δ属冠状病毒

36340.33
7Middle   East Respiratory Syndrome Coronavirus (MERS-CoV): Announcement of the   Coronavirus Study GroupJOURNAL   OF VIROLOGY2013

10.1128/JVI.01244-13

标题:

冠状病毒研究小组的宣布新的冠状病毒为:中东呼吸系统综合征病毒

33141.38
8Evidence  of human coronavirus HKU1 and human bocavirus in Australian childrenJOURNAL   OF CLINICAL VIROLOGY2006

10.1016/j.jcv.2005.09.008

标题:

在澳大利亚儿童中发现存在人类冠状病毒HKU1和人类博卡病毒的证据

309

20.6
9Evidence   for Camel-to-Human Transmission of MERS CoronavirusNEW   ENGLAND JOURNAL OF MEDICINE2014

10.1056/NEJMoa1401505

标题:研究找到中东呼吸系统综合征病毒是由骆驼传染到人类的证据

30042.86
10Middle   East respiratory syndrome coronavirus in dromedary camels: an outbreak   investigationLANCET   INFECTIOUS DISEASES2014

10.1016/S1473-3099(13)70690-X


标题:中东呼吸系统综合征疾病爆发研究表明:中东呼吸系统综合征病毒来自单峰骆驼

29742.43


二、研究结果分析

(一)可视化研究方向:

visualization (1).jpg

(二)研究方向记录数和占比

字段: 研究方向记录数%/1,850

INFECTIOUS DISEASES

传染病学

1,835 99.19%

MICROBIOLOGY

微生物学

1,183 63.95%

VIROLOGY

病毒学

1,135 61.35%

RESPIRATORY SYSTEM

呼吸系统疾病

996 53.84%

BIOCHEMISTRY MOLECULAR BIOLOGY

生物化学分子生物学

904 48.87%

IMMUNOLOGY

免疫学

868 46.92%

PUBLIC ENVIRONMENTAL OCCUPATIONAL HEALTH

公共环境与职业健康学

820 44.32%

GENETICS HEREDITY

遗传基因学

819 44.27%

VETERINARY SCIENCES

兽医学

707 38.22%

ENVIRONMENTAL SCIENCES ECOLOGY

环境生态学

531 28.70%

PATHOLOGY

病理学

508 27.46%

(三)研究地区及国家:

美国最多、其次是中国、沙特阿拉伯、韩国、德国等


visualization (2).jpg

(四)来源出版物

EMERGING INFECTIOUS DISEASES、JOURNAL OF VIROLOGY、VIROLOGY、PLOS ONE、JOURNAL OF CLINICAL MICROBIOLOGY等

visualization (3).jpg


(五)研究机构情况

香港大学(UNIVERSITY OF HONG KONG、UNIV HONG KONG)、沙特阿拉伯卫生部(MINIST HLTH)、美国疾病预防控制中心(CENTERS FOR DISEASE CONTROL PREVENTION USA )、沙特阿拉伯卫生部(MINISTRY OF HEALTH SAUDI ARABIA)等

 

visualization (4).jpg


   (六)近期收录的前50篇论文


1.

Full-genome evolutionary analysis of the novel corona virus (2019-nCoV) rejects the hypothesis of emergence as a result of a recent recombination event

作者Paraskevis, D.Kostaki, E. G.Magiorkinis, G.; .

INFECTION GENETICS AND EVOLUTION  : 79     文献号: 104212   出版年: APR 2020

 

被引频次: 0
 2

2.

Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan

作者Chan, Jasper Fuk-WooKok, Kin-HangZhu, Zheng; .

EMERGING MICROBES & INFECTIONS  : 9   : 1   : 221-236   出版年: JAN 1 2020

被引频次1 
 3

3.

Middle East Respiratory Syndrome Coronavirus Antibodies in Bactrian and Hybrid Camels from Dubai

作者Lau, Susanna K. P.Li, Kenneth S. M.Luk, Hayes Kam Hei; .

MSPHERE  : 5   : 1     文献号: e00898-19   出版年: JAN-FEB 2020

被引频次: 0
 4

4.

Parallel Simulation Decision-Making Method for a Response to Unconventional Public Health Emergencies Based on the Scenario-Response Paradigm and Discrete Event System Theory

作者Xie, TianNi, MengnaZhang, Zhaoyun; .

DISASTER MEDICINE AND PUBLIC HEALTH PREPAREDNESS  : 13   : 5-6   : 1017-1027   文献号: PII S1935789319000302   出版年: DEC 2019

 

被引频次: 0
 5

5.

Evaluation of serological assays available in a biosafety level 2 laboratory and their application for survey of Middle East respiratory syndrome coronavirus among livestock in Ethiopia

作者Teramichi, TakurouFukushi, ShuetsuHachiya, Yuma; .

JOURNAL OF VETERINARY MEDICAL SCIENCE  : 81   : 12   : 1887-1891   出版年: DEC 2019

被引频次: 0
 6

6.

Entry of Scotophilus Bat Coronavirus-512 and Severe Acute Respiratory Syndrome Coronavirus in Human and Multiple Animal Cells

作者Chen, Yi-NingHsu, Hsiao-ChinWang, Sheng-Wei; .

PATHOGENS  : 8   : 4     文献号: 259   出版年: DEC 2019

被引频次: 0
 7

7.

Middle East Respiratory Syndrome Coronavirus-Encoded ORF8b Inhibits RIG-I-Like Receptors by a Differential Mechanism

作者Lee, Jeong YoonKim, Seong-JunMyoung, Jinjong

JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY  : 29   : 12   : 2014-2021   出版年: DEC 2019

 

被引频次: 0
 8

8.

Middle East Respiratory Syndrome Coronavirus Seropositivity in Camel Handlers and Their Families, Pakistan

作者Zheng, JianHassan, SohailAlagaili, Abdulaziz N.; .

EMERGING INFECTIOUS DISEASES  : 25   : 12   : 2307-2309   出版年: DEC 2019

被引频次: 0
 9

9.

MERS-CoV in Camels but Not Camel Handlers, Sudan, 2015 and 2017

作者Farag, ElmoubasherSikkema, Reina S.Mohamedani, Ahmed A.; .

EMERGING INFECTIOUS DISEASES  : 25   : 12   : 2333-2335   出版年: DEC 2019

被引频次: 0
 10

10.

Effects of environmental disinfection on the isolation of vancomycin-resistant Enterococcus after a hospital-associated outbreak of Middle East respiratory syndrome

作者Ko, Jae-HoonKim, Si-HoLee, Nam Yong; .

AMERICAN JOURNAL OF INFECTION CONTROL  : 47   : 12   : 1516-1518   出版年: DEC 2019

 

被引频次: 0
 11

11.

A systematic review of MERS-CoV seroprevalence and RNA prevalence in dromedary camels: Implications for animal vaccination

作者Dighe, AmyJombart, ThibautVan Kerkhove, Maria D.; .

EPIDEMICS  : 29     文献号: UNSP 100350   出版年: DEC 2019

被引频次2 
 12

12.

Identifying potential emerging threats through epidemic intelligence activities-looking for the needle in the haystack?

作者Wilburn, JenniferO'Connor, CatherineWalsh, Amanda L.; .

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES  : 89   : 146-153   出版年: DEC 2019

被引频次: 0
 13

13.

Detection of MERS-CoV antigen on formalin-fixed paraffin-embedded nasal tissue of alpacas by immunohistochemistry using human monoclonal antibodies directed against different epitopes of the spike protein

作者Haverkamp, Ann-KathrinBosch, Berend J.Spitzbarth, Ingo; .

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY  : 218     文献号: UNSP 109939   出版年: DEC 2019

 

被引频次: 0
 14

14.

Diversity of Dromedary Camel Coronavirus HKU23 in African Camels Revealed Multiple Recombination Events among Closely Related Betacoronaviruses of the Subgenus Embecovirus

作者So, Ray T. Y.Chu, Daniel K. W.Miguel, Eve; .

JOURNAL OF VIROLOGY  : 93   : 23     文献号: e01236-19   出版年: DEC 2019

被引频次: 0
 15

15.

The 3.1-Angstrom Cryo-electron Microscopy Structure of the Porcine Epidemic Diarrhea Virus Spike Protein in the Prefusion Conformation

作者Wrapp, DanielMcLellan, Jason S.

JOURNAL OF VIROLOGY  : 93   : 23     文献号: e00923-19   出版年: DEC 2019

被引频次: 0
 16

16.

Humoral Immunogenicity and Efficacy of a Single Dose of ChAdOx1 MERS Vaccine Candidate in Dromedary Camels

作者Alharbi, Naif KhalafQasim, IbrahimAlmasoud, Abdulrahman; .

SCIENTIFIC REPORTS  : 9     文献号: 16292   出版年: NOV 8 2019

被引频次: 0
 17

17.

Causative agents and epidemiology of diarrhea in Korean native calves

作者Lee, Sung-HwanKim, Ha-YoungChoi, Eun Wha; .

JOURNAL OF VETERINARY SCIENCE  : 20   : 6     文献号: UNSP e64   出版年: NOV 2019

被引频次: 0
 18

18.

Identification of a Novel Betacoronavirus (Merbecovirus) in Amur Hedgehogs from China

作者Lau, Susanna K. P.Luk, Hayes K. H.Wong, Antonio C. P.; .

VIRUSES-BASEL  : 11   : 11     文献号: 980   出版年: NOV 2019

被引频次: 0
 19

19.

Diagnostic delays in Middle East respiratory syndrome coronavirus patients and health systems

作者Ahmed, Anwar E.

JOURNAL OF INFECTION AND PUBLIC HEALTH  : 12   : 6   : 767-771   出版年: NOV-DEC 2019

被引频次: 0
 20

20.

Coronaviruses as the cause of respiratory infections

作者Corman, V. M.Lienau, J.Witzenrath, M.

INTERNIST  : 60   : 11   : 1136-1145   出版年: NOV 2019

被引频次: 0
 21

21.

Bovine coronavirus in Uruguay: genetic diversity, risk factors and transboundary introductions from neighboring countries

作者Castells, MatiasGiannitti, FedericoCaffarena, Ruben Dario; .

ARCHIVES OF VIROLOGY  : 164   : 11   : 2715-2724   出版年: NOV 2019

被引频次1 
 22

22.

Transmissibility of MERS-CoV Infection in Closed Setting, Riyadh, Saudi Arabia, 2015

作者Van Kerkhove, Maria D.Aswad, SadoofAssiri, Abdullah; .

EMERGING INFECTIOUS DISEASES  : 25   : 10   : 1802-1809   出版年: OCT 2019

被引频次: 0
 23

23.

Sensitive and Specific Detection of Low-Level Antibody Responses in Mild Middle East Respiratory Syndrome Coronavirus Infections

作者Okba, Nisreen M. A.Raj, V. StalinWidjaja, Ivy; .

EMERGING INFECTIOUS DISEASES  : 25   : 10   : 1868-1877   出版年: OCT 2019

被引频次5 
 24

24.

Comparison of Serologic Assays for Middle East Respiratory Syndrome Coronavirus

作者Harvey, RuthMattiuzzo, GiadaHassall, Mark; .

团体作者: Study Participants

EMERGING INFECTIOUS DISEASES  : 25   : 10   : 1878-1883   出版年: OCT 2019

被引频次: 0
 25

25.

Viruses and Bats

作者Woo, Patrick C. Y.Lau, Susanna K. P.

VIRUSES-BASEL  : 11   : 10     文献号: 884   出版年: OCT 2019

被引频次: 0
 26

26.

Detection and characterization of a novel bat-borne coronavirus in Singapore using multiple molecular approaches

作者Lim, Xiao FangLee, Chengfa BenjaminPascoe, Sarah Marie; .

JOURNAL OF GENERAL VIROLOGY  : 100   : 10   : 1363-1374   出版年: OCT 2019

 

被引频次2 
 27

27.

Vaccine against Middle East respiratory syndrome coronavirus

作者Shen, XuejuanSabir, Jamal S. M.Irwin, David M.; .

LANCET INFECTIOUS DISEASES  : 19   : 10   : 1053-1054   出版年: OCT 2019

被引频次: 0
 28

28.

Middle East respiratory syndrome coronavirus in the last two years: Health care workers still at risk

作者Al-Tawfiq, Jaffar A.Memish, Ziad A.

AMERICAN JOURNAL OF INFECTION CONTROL  : 47   : 10   : 1167-1170   出版年: OCT 2019

 

被引频次1 
 29

29.

Assessing exhibition swine as potential disseminators of infectious disease through the detection of five respiratory pathogens at agricultural exhibitions

作者Lauterbach, Sarah E.Nelson, Sarah W.Robinson, Meghann E.; .

VETERINARY RESEARCH  : 50   : 1     文献号: 63   出版年: SEP 18 2019

被引频次: 0
 30

30.

A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence

作者Shen, ZhouWang, GangYang, Yiling; .

JOURNAL OF BIOLOGICAL CHEMISTRY  : 294   : 37   : 13606-13618   出版年: SEP 13 2019

 

被引频次: 0
 31

31.

First Report of Coronaviruses in Northern European Bats

作者Kivisto, IlkkaTidenberg, Eeva-MariaLilley, Thomas; .

VECTOR-BORNE AND ZOONOTIC DISEASES    

http://images.webofknowledge.com/WOKRS534DR1/images/zh_CN/earlyaccessicon.png在线发表日期: SEP 2019

 

被引频次: 0
 32

32.

Risk of Introduction of Infectious Animal Diseases for Europe Based on the Health Situation of North Africa and the Arabian Peninsula

作者Masso Sagues, ElenaFernandez-Carrion, EduardoManuel Sanchez-Vizcaino, Jose

FRONTIERS IN VETERINARY SCIENCE  : 6     文献号: 293   出版年: SEP 4 2019

被引频次: 0
 33

33.

Health risk assessment at mass gatherings: a report of the camel festival in Saudi Arabia

作者Bieh, KingsleyElGanainy, AhmedYezli, Saber; .

EASTERN MEDITERRANEAN HEALTH JOURNAL  : 25   : 9   : 647-655   出版年: SEP 2019

被引频次1 
 34

34.

Crystal structure of the S1 subunit N-terminal domain from DcCoV UAE-HKU23 spike protein

作者Cheng, YanweiHe, BinYang, Jing; .

VIROLOGY  : 535   : 74-82   出版年: SEP 2019

 

被引频次: 0
 35

35.

Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial

作者Modjarrad, KayvonRoberts, Christine C.Mills, Kristin T.; .

LANCET INFECTIOUS DISEASES  : 19   : 9   : 1013-1022   出版年: SEP 2019

 

被引频次4 
 36

36.

Main factors influencing recovery in MERS Co-V patients using machine learning

作者John, MayaShaiba, Hadil

JOURNAL OF INFECTION AND PUBLIC HEALTH  : 12   : 5   : 700-704   出版年: SEP-OCT 2019

被引频次: 0
 37

37.

Risk Factors for Fatal Middle East Respiratory Syndrome Coronavirus Infections in Saudi Arabia: Analysis of the WHO Line List, 2013-2018

作者Rahman, ArifurSarkar, Atanu

AMERICAN JOURNAL OF PUBLIC HEALTH  : 109   : 9   : 1288-1293   出版年: SEP 2019

 

被引频次1 
 38

38.

Detection of multiple viral sequences in the respiratory tract samples of suspected Middle East respiratory syndrome coronavirus patients in Jakarta, Indonesia 2015-2016

作者Setianingsih, Tri YuliWiyatno, AgengHartono, Teguh Sarry; .

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES  : 86   : 102-107   出版年: SEP 2019

被引频次: 0
 39

39.

Prevalence of a novel bovine coronavirus strain with a recombinant hemagglutinin/esterase gene in dairy calves in China

作者Keha, AbiXue, LuoYan, Shen; .

TRANSBOUNDARY AND EMERGING DISEASES  : 66   : 5   : 1971-1981   出版年: SEP 2019

被引频次3 
 40

40.

Spike proteins of novel MERS-coronavirus isolates from North- and West-African dromedary camels mediate robust viral entry into human target cells

作者Kleine-Weber, HannahPoehlmann, StefanHoffmann, Markus

VIROLOGY  : 535   : 261-265   出版年: SEP 2019

 

被引频次: 0
 41

41.

Worldwide Reduction in MERS Cases and Deaths since 2016

作者Donnelly, Christl A.Malik, Mamun R.Elkholy, Amgad; .

EMERGING INFECTIOUS DISEASES  : 25   : 9   : 1758-1760   出版年: SEP 2019

被引频次: 0
 42

42.

Cricket paralysis virus internal ribosome entry site-derived RNA promotes conventional vaccine efficacy by enhancing a balanced Th1/Th2 response

作者Kwak, Hye WonPark, Hyo-JungKo, Hae Li; .

VACCINE  : 37   : 36   : 5191-5202   出版年: AUG 23 2019

 

被引频次1 
 43

43.

Identification of Diverse Bat Alphacoronaviruses and Betacoronaviruses in China Provides New Insights Into the Evolution and Origin of Coronavirus-Related Diseases

作者Han, YelinDu, JiangSu, Haoxiang; .

FRONTIERS IN MICROBIOLOGY  : 10     文献号: 1900   出版年: AUG 14 2019

被引频次: 0
 44

44.

Identification and full-genome characterization of Alpha- and Beta-Coronaviruses viruses from bats in Italy

作者De Sabato, L.Vaccari, G.Lelli, D.; .

VIRUS EVOLUTION  : 5   增刊: 1   : S15-S15   会议摘要: A48   出版年: AUG 2019

被引频次: 0
 45

45.

A Yeast Suppressor Screen Used To Identify Mammalian SIRT1 as a Proviral Factor for Middle East Respiratory Syndrome Coronavirus Replication

作者Weston, StuartMatthews, Krystal L.Lent, Rachel; .

JOURNAL OF VIROLOGY  : 93   : 16     文献号: e00197-19   出版年: AUG 2019

 

被引频次: 0
 46

46.

Species-Specific Colocalization of Middle East Respiratory Syndrome Coronavirus Attachment and Entry Receptors

作者Widagdo, W.Okba, Nisreen M. A.Li, Wentao; .

JOURNAL OF VIROLOGY  : 93   : 16     文献号: e00107-19   出版年: AUG 2019

 

被引频次1 
 47

47.

Effectiveness of an education health programme about Middle East respiratory syndrome coronavirus tested during travel consultations

作者Migault, C.Kanagaratnam, L.Hentzien, M.; .

PUBLIC HEALTH  : 173   : 29-32   出版年: AUG 2019

被引频次: 0
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48.

Complete genome analysis of a SARS-like bat coronavirus identified in the Republic of Korea

作者Kim, YongkwanSon, KidongKim, Young-Sik; .

VIRUS GENES  : 55   : 4   : 545-549   出版年: AUG 2019

被引频次: 0
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49.

Migrating a lab-developed MERS-CoV real-time PCR to 3 "Sample to Result" systems: experiences on optimization and validation

作者Frans, GlynisBeuselinck, KurtPeeters, Bart; .

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE  : 94   : 4   : 349-354   出版年: AUG 2019

 

被引频次1 
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50.

Acute phase response in bovine coronavirus positive post-weaned calves with diarrhea

作者Chae, Jeong-ByoungPark, JinhoJung, Suk-Han; .

ACTA VETERINARIA SCANDINAVICA  : 61     文献号: 36   出版年: JUL 25 2019

被引频次: 0
 












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