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氢气分子医学文献汇总(2013/2/23)

已有 5751 次阅读 2013-2-23 17:17 |个人分类:氢气生物学|系统分类:科研笔记| style, 医学

 

2007Ohsawa I发表在Nat Med上的论文,目前在WOS上被引用次数达到222次,引用次数在所有2007年至今Nat Med杂志发表的2801篇各类文章中总排第35名。在google上引用次数已经达到390次,在scopus引用已经达到258 次。以下为WOS上引用文献的目录,几乎90%属于氢气生物学效应研究论文和相关综述,整理出来供大家参考使用。

 

1.         Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, Yamagata K, Katsura K, Katayama Y, Asoh S, Ohta S. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med. 2007;13:688-694

2.         Ball J. Recently published papers: More about egdt, experimental therapies and some inconvenient truths. Critical Care. 2007;11

3.         Fukuda KI, Asoh S, Ishikawa M, Yamamoto Y, Ohsawa I, Ohta S. Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress. Biochemical and biophysical research communications. 2007;361:670-674

4.         Wood KC, Gladwin MT. The hydrogen highway to reperfusion therapy. Nature Medicine. 2007;13:673-674

5.         Buchholz BM, Kaczorowski DJ, Sugimoto R, Yang R, Wang Y, Billiar TR, McCurry KR, Bauer AJ, Nakao A. Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury. American Journal of Transplantation. 2008;8:2015-2024

6.         Cai JM, Kang ZM, Liu WW, Luo X, Qiang S, Zhang JH, Ohta SG, Sun XJ, Xu WG, Tao HY, Li RP. Hydrogen therapy reduces apoptosis in neonatal hypoxia-ischemia rat model. Neuroscience letters. 2008;441:167-172

7.         Fukuyo Y, Inoue M, Nakajima T, Higashikubo R, Horikoshi NT, Hunt C, Usheva A, Freeman ML, Horikoshi N. Oxidative stress plays a critical role in inactivating mutant braf by geldanamycin derivatives. Cancer Research. 2008;68:6324-6330

8.         Hayashida K, Sano M, Ohsawa I, Shinmura K, Tamaki K, Kimura K, Endo J, Katayama T, Kawamura A, Kohsaka S, Makino S, Ohta S, Ogawa S, Fukuda K. Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury. Biochemical and biophysical research communications. 2008;373:30-35

9.         Kajiyama S, Hasegawa G, Asano M, Hosoda H, Fukui M, Nakamura N, Kitawaki J, Imai S, Nakano K, Ohta M, Adachi T, Obayashi H, Yoshikawa T. Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutrition Research. 2008;28:137-143

10.     Katsura KI, Takahashi K, Asoh S, Watanabe M, Sakurazawa M, Ohsawa I, Mori T, Igarashi H, Ohkubo S, Katayama Y, Ohta S. Combination therapy with transductive anti-death fnk protein and fk506 ameliorates brain damage with focal transient ischemia in rat. Journal of neurochemistry. 2008;106:258-270

11.     Ohsawa I, Nishimaki K, Murakami Y, Suzuki Y, Ishikawa M, Ohta S. Age-dependent neurodegeneration accompanying memory loss in transgenic mice defective in mitochondrial aldehyde dehydrogenase 2 activity. Journal of Neuroscience. 2008;28:6239-6249

12.     Ohsawa I, Nishimaki K, Yamagata K, Ishikawa M, Ohta S. Consumption of hydrogen water prevents atherosclerosis in apolipoprotein e knockout mice. Biochemical and biophysical research communications. 2008;377:1195-1198

13.     Renault JP, Vuilleumier R, Pommeret S. Hydrated electron production by reaction of hydrogen atoms with hydroxide ions: A first-principles molecular dynamics study. Journal of Physical Chemistry A. 2008;112:7027-7034

14.     Saitoh Y, Okayasu H, Xiao L, Harata Y, Miwa N. Neutral ph hydrogen-enriched electrolyzed water achieves tumor-preferential clonal growth inhibition over normal cells and tumor invasion inhibition concurrently with intracellular oxidant repression. Oncology Research. 2008;17:247-255

15.     Sato Y, Kajiyama S, Amano A, Kondo Y, Sasaki T, Handa S, Takahashi R, Fukui M, Hasegawa G, Nakamura N, Fujinawa H, Mori T, Ohta M, Obayashi H, Maruyama N, Ishigami A. Hydrogen-rich pure water prevents superoxide formation in brain slices of vitamin c-depleted smp30/gnl knockout mice. Biochemical and biophysical research communications. 2008;375:346-350

16.     Ye J, Li Y, Hamasaki T, Nakamichi N, Komatsu T, Kashiwagi T, Teruya K, Nishikawa R, Kawahara T, Osada K, Toh K, Abe M, Tian H, Kabayama S, Otsubo K, Morisawa S, Katakura Y, Shirahata S. Inhibitory effect of electrolyzed reduced water on tumor angiogenesis. Biological & pharmaceutical bulletin. 2008;31:19-26

17.     Bocci V, Borrelli E, Travagli V, Zanardi I. The ozone paradox: Ozone is a strong oxidant as well as a medical drug. Medicinal Research Reviews. 2009;29:646-682

18.     Cai JM, Kang ZM, Liu K, Liu WW, Li RP, Zhang JH, Luo X, Sun XJ. Neuroprotective effects of hydrogen saline in neonatal hypoxia-ischemia rat model. Brain research. 2009;1256:129-137

19.     Cheng Y, Qiu F, Ye YC, Guo ZM, Tashiro SI, Onodera S, Ikejima T. Autophagy inhibits reactive oxygen species-mediated apoptosis via activating p38-nuclear factor-kappa b survival pathways in oridonin-treated murine fibrosarcoma l929 cells. Febs Journal. 2009;276:1291-1306

20.     Fu Y, Ito M, Fujita Y, Ichihara M, Masuda A, Suzuki Y, Maesawa S, Kajita Y, Hirayama M, Ohsawa I, Ohta S, Ohno K. Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of parkinson's disease. Neuroscience letters. 2009;453:81-85

21.     Fujita K, Seike T, Yutsudo N, Ohno M, Yamada H, Yamaguchi H, Sakumi K, Yamakawa Y, Kido MA, Takaki A, Katafuchi T, Tanaka Y, Nakabeppu Y, Noda M. Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of parkinson's disease. PloS one. 2009;4

22.     Itoh T, Fujita Y, Ito M, Masuda A, Ohno K, Ichihara M, Kojima T, Nozawa Y. Molecular hydrogen suppresses fc epsilon ri-mediated signal transduction and prevents degranulation of mast cells. Biochemical and biophysical research communications. 2009;389:651-656

23.     Kajiya M, Sato K, Silva MJB, Ouhara K, Do PM, Shanmugam KT, Kawai T. Hydrogen from intestinal bacteria is protective for concanavalin a-induced hepatitis. Biochemical and biophysical research communications. 2009;386:316-321

24.     Kajiya M, Silva MJB, Sato K, Ouhara K, Kawai T. Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate. Biochemical and biophysical research communications. 2009;386:11-15

25.     Kawahito S, Kitahata H, Oshita S. Problems associated with glucose toxicity: Role of hyperglycemia-induced oxidative stress. World Journal of Gastroenterology. 2009;15:4137-4142

26.     Kikkawa YS, Nakagawa T, Horie RT, Ito J. Hydrogen protects auditory hair cells from free radicals. Neuroreport. 2009;20:689-694

27.     Kikuchi K, Ioka A, Oku T, Tanaka Y, Saihara Y, Ogumi Z. Concentration determination of oxygen nanobubbles in electrolyzed water. Journal of colloid and interface science. 2009;329:306-309

28.     Li DJ, Tang Q, Shen FM, Su DF, Duan JL, Xi T. Overexpressed alpha 7 nicotinic acetylcholine receptor inhibited proinflammatory cytokine release in nih3t3 cells. Journal of Bioscience and Bioengineering. 2009;108:85-91

29.     Mao YF, Zheng XF, Cai JM, You XM, Deng XM, Zhang JH, Jiang L, Sun XJ. Hydrogen-rich saline reduces lung injury induced by intestinal ischemia/reperfusion in rats. Biochemical and biophysical research communications. 2009;381:602-605

30.     Matchett GA, Fathali N, Hasegawa Y, Jadhav V, Ostrowski RP, Martin RD, Dorotta IR, Sun XJ, Zhang JH. Hydrogen gas is ineffective in moderate and severe neonatal hypoxia-ischemia rat models. Brain research. 2009;1259:90-97

31.     Nagata K, Nakashima-Kamimura N, Mikami T, Ohsawa I, Ohta S. Consumption of molecular hydrogen prevents the stress-induced impairments in hippocampus-dependent learning tasks during chronic physical restraint in mice. Neuropsychopharmacology. 2009;34:501-508

32.     Nakao A, Sugimoto R, Billiar TR, McCurry KR. Therapeutic antioxidant medical gas. Journal of Clinical Biochemistry and Nutrition. 2009;44:1-13

33.     Nakashima-Kamimura N, Mori T, Ohsawa I, Asoh S, Ohta S. Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice. Cancer Chemotherapy and Pharmacology. 2009;64:753-761

34.     Nakayama M, Kabayama S, Nakano H, Zhu WJ, Terawaki H, Nakayama K, Katoh K, Satoh T, Ito S. Biological effects of electrolyzed water in hemodialysis. Nephron Clinical Practice. 2009;112:C9-C15

35.     Saiki R, Nishimura K, Ishii I, Omura T, Okuyama S, Kashiwagi K, Igarashi K. Intense correlation between brain infarction and protein-conjugated acrolein. Stroke; a journal of cerebral circulation. 2009;40:3356-3361

36.     Shimouchi A, Nose K, Takaoka M, Hayashi H, Kondo T. Effect of dietary turmeric on breath hydrogen. Digestive Diseases and Sciences. 2009;54:1725-1729

37.     Sun Q, Kang ZM, Cai JM, Liu WW, Liu Y, Zhang JH, Denoble PJ, Tao HY, Sun XJ. Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats. Experimental Biology and Medicine. 2009;234:1212-1219

38.     Suzuki Y, Sano M, Hayashida K, Ohsawa I, Ohta S, Fukuda K. Are the effects of alpha-glucosidase inhibitors on cardiovascular events related to elevated levels of hydrogen gas in the gastrointestinal tract? FEBS letters. 2009;583:2157-2159

39.     Wagner F, Asfar P, Calzia E, Radermacher P, Szabo C. Bench-to-bedside review: Hydrogen sulfide - the third gaseous transmitter: Applications for critical care. Critical Care. 2009;13

40.     Yun YH, Dong ZY, Lee N, Liu YJ, Xue DC, Guo XF, Kuhlmann J, Doepke A, Halsall HB, Heineman W, Sundaramurthy S, Schulz MJ, Yin ZZ, Shanov V, Hurd D, Nagy P, Li WF, Fox C. Revolutionizing biodegradable metals. Materials Today. 2009;12:22-32

41.     Zheng XF, Mao YF, Cai JM, Li YH, Liu WW, Sun PL, Zhang JH, Sun XJ, Yuan HB. Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats. Free radical research. 2009;43:478-484

42.     Cardinal JS, Zhan JH, Wang YN, Sugimoto R, Tsung A, McCurry KR, Billiar TR, Nakao A. Oral hydrogen water prevents chronic allograft nephropathy in rats. Kidney International. 2010;77:101-109

43.     Chen CH, Manaenko A, Zhan Y, Liu WW, Ostrowki RP, Tang J, Zhang JH. Hydrogen gas reduced acute hyperglycemia-enhanced hemorrhagic transformation in a focal ischemia rat model. Neuroscience. 2010;169:402-414

44.     Chen CW, Chen QB, Mao YF, Xu SM, Xia CY, Shi XY, Zhang JH, Yuan HB, Sun XJ. Hydrogen-rich saline protects against spinal cord injury in rats. Neurochemical research. 2010;35:1111-1118

45.     Chen H, Sun YP, Li Y, Liu WW, Xiang HG, Fan LY, Sun Q, Xu XY, Cai JM, Ruan CP, Su N, Yan RL, Sun XJ, Wang Q. Hydrogen-rich saline ameliorates the severity of l-arginine-induced acute pancreatitis in rats. Biochemical and biophysical research communications. 2010;393:308-313

46.     Domoki F, Olah O, Zimmermann A, Nemeth I, Toth-Szuki V, Hugyecz M, Temesvari P, Bart F. Hydrogen is neuroprotective and preserves cerebrovascular reactivity in asphyxiated newborn pigs. Pediatric Research. 2010;68:387-392

47.     Farhana A, Guidry L, Srivastava A, Singh A, Hondalus MK, Steyn AJC. Reductive stress in microbes: Implications for understanding mycobacterium tuberculosis disease and persistence. In: Poole RK, ed. Advances in microbial physiology, vol 57. 2010:43-117.

48.     Fukuyo Y, Hunt CR, Horikoshi N. Geldanamycin and its anti-cancer activities. Cancer Letters. 2010;290:24-35

49.     George JF, Agarwal A. Hydrogen: Another gas with therapeutic potential. Kidney International. 2010;77:85-87

50.     Gu Y, Huang CS, Inoue T, Yamashita T, Ishida T, Kang KM, Nakao A. Drinking hydrogen water ameliorated cognitive impairment in senescence-accelerated mice. Journal of Clinical Biochemistry and Nutrition. 2010;46:269-276

51.     Hiraoka A, Inaba H, Suzuki E, Kasai K, Suzuki H, Shinohara A, Shirao M, Kubo K, Yoshimura Y. In vitro physicochemical properties of neutral aqueous solution systems (water products as drinks) containing hydrogen gas, 2-carboxyethyl germanium sesquioxide, and platinum nanocolloid as additives. Journal of Health Science. 2010;56:167-174

52.     Hong Y, Chen S, Zhang JM. Hydrogen as a selective antioxidant: A review of clinical and experimental studies. Journal of International Medical Research. 2010;38:1893-1903

53.     Huang CS, Kawamura T, Lee S, Tochigi N, Shigemura N, Buchholz BM, Kloke JD, Billiar TR, Toyoda Y, Nakao A. Hydrogen inhalation ameliorates ventilator-induced lung injury. Critical Care. 2010;14

54.     Huang CS, Kawamura T, Toyoda Y, Nakao A. Recent advances in hydrogen research as a therapeutic medical gas. Free radical research. 2010;44:971-982

55.     Ji XT, Liu WB, Xie KL, Liu WP, Qu Y, Chao XD, Chen T, Zhou J, Fei Z. Beneficial effects of hydrogen gas in a rat model of traumatic brain injury via reducing oxidative stress. Brain research. 2010;1354:196-205

56.     Kanazuru T, Sato EF, Nagata K, Matsui H, Watanabe K, Kasahara E, Jikumaru M, Inoue J, Inoue M. Role of hydrogen generation by klebsiella pneumoniae in the oral cavity. Journal of Microbiology. 2010;48:778-783

57.     Kang N, Zhang JH, Qiu F, Tashiro S, Onodera S, Ikejima T. Inhibition of egfr signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways. Cancer Letters. 2010;294:147-158

58.     Kawamura T, Huang CS, Tochigi N, Lee S, Shigemura N, Billiar TR, Okumura M, Nakao A, Toyoda Y. Inhaled hydrogen gas therapy for prevention of lung transplant-induced ischemia/reperfusion injury in rats. Transplantation. 2010;90:1344-1351

59.     Kawasaki H, Guan JJ, Tamama K. Hydrogen gas treatment prolongs replicative lifespan of bone marrow multipotential stromal cells in vitro while preserving differentiation and paracrine potentials. Biochemical and biophysical research communications. 2010;397:608-613

60.     Kitamura A, Kobayashi S, Matsushita T, Fujinawa H, Murase K. Experimental verification of protective effect of hydrogen-rich water against cisplatin-induced nephrotoxicity in rats using dynamic contrast-enhanced ct. British Journal of Radiology. 2010;83:509-514

61.     Li J, Wang C, Zhang JH, Cai JM, Cao YP, Sun XJ. Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced alzheimer's disease by reduction of oxidative stress. Brain research. 2010;1328:152-161

62.     Liu C, Cui JG, Sun Q, Cai JM. Hydrogen therapy may be an effective and specific novel treatment for acute radiation syndrome. Medical hypotheses. 2010;74:145-146

63.     Liu Q, Shen WF, Sun HY, Fan DF, Nakao A, Cai JM, Yan G, Zhou WP, Shen RX, Yang JM, Sun XJ. Hydrogen-rich saline protects against liver injury in rats with obstructive jaundice. Liver International. 2010;30:958-968

64.     Liu SL, Sun QA, Tao HY, Sun XJ. Oral administration of mannitol may be an effective treatment for ischemia-reperfusion injury. Medical hypotheses. 2010;75:620-622

65.     Low SP, Williams KA, Canham LT, Voelcker NH. Generation of reactive oxygen species from porous silicon microparticles in cell culture medium. Journal of Biomedical Materials Research Part A. 2010;93A:1124-1131

66.     Lu JM, Lin PH, Yao QZ, Chen CY. Chemical and molecular mechanisms of antioxidants: Experimental approaches and model systems. Journal of Cellular and Molecular Medicine. 2010;14:840-860

67.     Nakao A, Kaczorowski DJ, Wang YN, Cardinal JS, Buchholz BM, Sugimoto R, Tobita K, Lee S, Toyoda Y, Billiar TR, McCurry KR. Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both. Journal of Heart and Lung Transplantation. 2010;29:544-553

68.     Nakao A, Toyoda Y, Sharma P, Evans M, Guthrie N. Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study. Journal of Clinical Biochemistry and Nutrition. 2010;46:140-149

69.     Nakayama M, Nakano H, Hamada H, Itami N, Nakazawa R, Ito S. A novel bioactive haemodialysis system using dissolved dihydrogen (h-2) produced by water electrolysis: A clinical trial. Nephrology Dialysis Transplantation. 2010;25:3026-3033

70.     Oharazawa H, Igarashi T, Yokota T, Fujii H, Suzuki H, Machide M, Takahashi H, Ohta S, Ohsawa I. Protection of the retina by rapid diffusion of hydrogen: Administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury. Investigative Ophthalmology & Visual Science. 2010;51:487-492

71.     Pandey BN, Kumar A, Tiwari P, Mishra KP. Radiobiological basis in management of accidental radiation exposure. International Journal of Radiation Biology. 2010;86:613-635

72.     Qian LR, Cao F, Cui JG, Huang YC, Zhou XJ, Liu SL, Cai JM. Radioprotective effect of hydrogen in cultured cells and mice. Free radical research. 2010;44:275-282

73.     Qian LR, Cao F, Cui JG, Wang YC, Huang YC, Chuai YH, Zaho LQ, Jiang H, Cai JM. The potential cardioprotective effects of hydrogen in irradiated mice. Journal of Radiation Research. 2010;51:741-747

74.     Qian LR, Li BL, Cai JM, Gao F. The hypothesis of an effective safe and novel radioprotective agent hydrogen-rich solution. West Indian Medical Journal. 2010;59:122-124

75.     Qian LR, Li BL, Cao F, Huang YC, Liu SL, Cai JM, Gao F. Hydrogen-rich pbs protects cultured human cells from ionizing radiation-induced cellular damage. Nuclear Technology & Radiation Protection. 2010;25:23-29

76.     Saitoh Y, Harata Y, Mizuhashi F, Nakajima M, Miwa N. Biological safety of neutral-ph hydrogen-enriched electrolyzed water upon mutagenicity, genotoxicity and subchronic oral toxicity. Toxicology and Industrial Health. 2010;26:203-216

77.     Santos HA, Riikonen J, Salonen J, Makila E, Heikkila T, Laaksonen T, Peltonen L, Lehto VP, Hirvonen J. In vitro cytotoxicity of porous silicon microparticles: Effect of the particle concentration, surface chemistry and size. Acta Biomaterialia. 2010;6:2721-2731

78.     Shen MH, He JA, Cai JM, Sun QA, Sun XJ, Huo ZL. Hydrogen as a novel and effective treatment of acute carbon monoxide poisoning. Medical hypotheses. 2010;75:235-237

79.     Shingu C, Koga H, Hagiwara S, Matsumoto S, Goto K, Yokoi I, Noguchi T. Hydrogen-rich saline solution attenuates renal ischemia-reperfusion injury. Journal of Anesthesia. 2010;24:569-574

80.     Taura A, Kikkawa YS, Nakagawa T, Ito J. Hydrogen protects vestibular hair cells from free radicals. Acta Oto-Laryngologica. 2010;130:95-100

81.     Ueda Y, Nakajima A, Oikawa T. Hydrogen-related enhancement of in vivo antioxidant ability in the brain of rats fed coral calcium hydride. Neurochemical research. 2010;35:1510-1515

82.     Weng YC, Hung KC, Wang JC, Lee YG, Su YF, Lin CY. Binary platinum-ruthenium/nafion electrodes for the detection of hydrogen. Sensors and Actuators B-Chemical. 2010;150:264-270

83.     Wolf AM, Asoh S, Hiranuma H, Ohsawa I, Iio K, Satou A, Ishikura M, Ohta S. Astaxanthin protects mitochondrial redox state and functional integrity against oxidative stress. Journal of Nutritional Biochemistry. 2010;21:381-389

84.     Xiang J, Tang YP, Wu P, Gao JP, Cai DF. Chinese medicine nao-shuan-tong attenuates cerebral ischemic injury by inhibiting apoptosis in a rat model of stroke. Journal of ethnopharmacology. 2010;131:174-181

85.     Xie KL, Yu YH, Pei YP, Hou LC, Chen SY, Xiong LZ, Wang GL. Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and hmgb1 release. Shock. 2010;34:90-97

86.     Xie KL, Yu YH, Zhang ZS, Liu WB, Pei YP, Xiong LZ, Hou LC, Wang GL. Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model. Shock. 2010;34:495-501

87.     Yan HX, Tian HZ, Kinjo T, Hamasaki T, Tomimatsu K, Nakamichi N, Teruya K, Kabayama S, Shirahata S. Extension of the lifespan of caenorhabditis elegans by the use of electrolyzed reduced water. Bioscience Biotechnology and Biochemistry. 2010;74:2011-2015

88.     Zheng J, Liu K, Kang ZM, Cai JM, Liu WW, Xu WG, Li RP, Tao HY, Zhang JH, Sun XJ. Saturated hydrogen saline protects the lung against oxygen toxicity. Undersea & Hyperbaric Medicine. 2010;37:185-192

89.     Zhou ZY, Tang YP, Xiang J, Wua P, Jin HM, Wang Z, Mori M, Cai DF. Neuroprotective effects of water-soluble ganoderma lucidum polysaccharides on cerebral ischemic injury in rats. Journal of ethnopharmacology. 2010;131:154-164

90.     Bimbo LM, Makila E, Laaksonen T, Lehto VP, Salonen J, Hirvonen J, Santos HA. Drug permeation across intestinal epithelial cells using porous silicon nanoparticles. Biomaterials. 2011;32:2625-2633

91.     Bocci V, Zanardi I, Travagli V. Ozone: A new therapeutic agent in vascular diseases. American Journal of Cardiovascular Drugs. 2011;11:73-82

92.     Buchholz BM, Masutani K, Kawamura T, Peng XM, Toyoda Y, Billiar TR, Bauer AJ, Nakao A. Hydrogen-enriched preservation protects the isogeneic intestinal graft and amends recipient gastric function during transplantation. Transplantation. 2011;92:985-992

93.     Chen H, Sun YP, Hu PF, Liu WW, Xiang HG, Li Y, Yan RL, Su N, Ruan CP, Sun XJ, Wang QA. The effects of hydrogen-rich saline on the contractile and structural changes of intestine induced by ischemia-reperfusion in rats. Journal of Surgical Research. 2011;167:316-322

94.     Chen XA, Zuo QA, Hai YD, Sun XJ. Lactulose: An indirect antioxidant ameliorating inflammatory bowel disease by increasing hydrogen production. Medical hypotheses. 2011;76:325-327

95.     Chuai YH, Zhao LQ, Ni J, Sun D, Cui JG, Li BL, Qian LR, Gao F, Cai JM. A possible prevention strategy of radiation pneumonitis: Combine radiotherapy with aerosol inhalation of hydrogen-rich solution. Medical Science Monitor. 2011;17:HY1-HY4

96.     Eltzschig HK, Eckle T. Ischemia and reperfusion-from mechanism to translation. Nature Medicine. 2011;17:1391-1401

97.     Fanelli V, Zhang H, Slutsky AS. Year in review 2010: Critical care - respirology. Critical Care. 2011;15

98.     Fang Y, Fu XJ, Gu C, Xu P, Wang Y, Yu WR, Sun Q, Sun XJ, Yao M. Hydrogen-rich saline protects against acute lung injury induced by extensive burn in rat model. Journal of Burn Care & Research. 2011;32:E82-E91

99.     Fujita R, Tanaka Y, Saihara Y, Yamakita M, Ando D, Koyama K. Effect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle. Journal of Physiological Anthropology. 2011;30:195-201

100.  Hayashi T, Yoshioka T, Hasegawa K, Miyamura M, Mori T, Ukimura A, Matsumura Y, Ishizaka N. Inhalation of hydrogen gas attenuates left ventricular remodeling induced by intermittent hypoxia in mice. American Journal of Physiology-Heart and Circulatory Physiology. 2011;301:H1062-H1069

101.  Huang CS, Kawamura T, Peng XM, Tochigi N, Shigemura N, Billiar TR, Nakao A, Toyoda Y. Hydrogen inhalation reduced epithelial apoptosis in ventilator-induced lung injury via a mechanism involving nuclear factor-kappa b activation. Biochemical and biophysical research communications. 2011;408:253-258

102.  Huang Y, Xie KL, Li JP, Xu N, Gong G, Wang GL, Yu YH, Dong HL, Xiong LZ. Beneficial effects of hydrogen gas against spinal cord ischemia-reperfusion injury in rabbits. Brain research. 2011;1378:125-136

103.  Hugyecz M, Mracsko E, Hertelendy P, Farkas E, Domoki F, Bari F. Hydrogen supplemented air inhalation reduces changes of prooxidant enzyme and gap junction protein levels after transient global cerebral ischemia in the rat hippocampus. Brain research. 2011;1404:31-38

104.  Itoh T, Hamada N, Terazawa R, Ito M, Ohno K, Ichihara M, Nozawa Y. Molecular hydrogen inhibits lipopolysaccharide/interferon gamma-induced nitric oxide production through modulation of signal transduction in macrophages. Biochemical and biophysical research communications. 2011;411:143-149

105.  Ji Q, Hui KL, Zhang LD, Sun XJ, Li WY, Duan ML. The effect of hydrogen-rich saline on the brain of rats with transient ischemia. Journal of Surgical Research. 2011;168:E95-E101

106.  Jiao L, Zhang J, Li Z, Liu H, Chen Y, Xu S. Edaravone alleviates delayed neuronal death and long-dated cognitive dysfunction of hippocampus after transient focal ischemia in wistar rat brains. Neuroscience. 2011;182:177-183

107.  Kamimura N, Nishimaki K, Ohsawa I, Ohta S. Molecular hydrogen improves obesity and diabetes by inducing hepatic fgf21 and stimulating energy metabolism in db/db mice. Obesity. 2011;19:1396-1403

108.  Kasuyama K, Tomofuji T, Ekuni D, Tamaki N, Azuma T, Irie K, Endo Y, Morita M. Hydrogen-rich water attenuates experimental periodontitis in a rat model. Journal of Clinical Periodontology. 2011;38:1085-1090

109.  Kohno M, Mokudai T, Ozawa T, Niwano Y. Free radical formation from sonolysis of water in the presence of different gases. Journal of Clinical Biochemistry and Nutrition. 2011;49:96-101

110.  Kubota M, Shimmura S, Kubota S, Miyashita H, Kato N, Noda K, Ozawa Y, Usui T, Ishida S, Umezawa K, Kurihara T, Tsubota K. Hydrogen and n-acetyl-l-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model. Investigative Ophthalmology & Visual Science. 2011;52:427-433

111.  Li QY, Jiang CF, Zu YG, Song Z, Zhang BY, Meng XD, Qiu W, Zhang L. Sfe-co2 extract from typhonium giganteum engl. Tubers, induces apoptosis in human hepatoma smmc-7721 cells involvement of a ros-mediated mitochondrial pathway. Molecules. 2011;16:8228-8242

112.  Li YP, Hamasaki T, Nakamichi N, Kashiwagi T, Komatsu T, Ye J, Teruya K, Abe M, Yan HX, Kinjo T, Kabayama S, Kawamura M, Shirahata S. Suppressive effects of electrolyzed reduced water on alloxan-induced apoptosis and type 1 diabetes mellitus. Cytotechnology. 2011;63:119-131

113.  Lin Y, Kashio A, Sakamoto T, Suzukawa K, Kakigi A, Yamasoba T. Hydrogen in drinking water attenuates noise-induced hearing loss in guinea pigs. Neuroscience letters. 2011;487:12-16

114.  Liu SL, Liu K, Sun QA, Liu WW, Xu WG, Denoble P, Tao HY, Sun XJ. Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats. Journal of Biomedicine and Biotechnology. 2011

115.  Matsushita T, Kusakabe Y, Kitamura A, Okada S, Murase K. Investigation of protective effect of hydrogen-rich water against cisplatin-induced nephrotoxicity in rats using blood oxygenation level-dependent magnetic resonance imaging. Japanese Journal of Radiology. 2011;29:503-512

116.  Matsushita T, Kusakabe Y, Kitamura A, Okada S, Murase K. Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent mr imaging. Magnetic Resonance in Medical Sciences. 2011;10:169-176

117.  Nakai Y, Sato B, Ushiama S, Okada S, Abe K, Arai S. Hepatic oxidoreduction-related genes are upregulated by administration of hydrogen-saturated drinking water. Bioscience Biotechnology and Biochemistry. 2011;75:774-776

118.  Ni XX, Cai ZY, Fan DF, Liu Y, Zhang RJ, Liu SL, Kang ZM, Liu K, Li RP, Sun XJ, Xu WG. Protective effect of hydrogen-rich saline on decompression sickness in rats. Aviation Space and Environmental Medicine. 2011;82:604-609

119.  Noda M, Fujita K, Lee CH, Yoshioka T. The principle and the potential approach to ros-dependent cytotoxicity by non-pharmaceutical therapies: Optimal use of medical gases with antioxidant properties. Current pharmaceutical design. 2011;17:2253-2263

120.  Ohta S. Recent progress toward hydrogen medicine: Potential of molecular hydrogen for preventive and therapeutic applications. Current pharmaceutical design. 2011;17:2241-2252

121.  Qiu XC, Li HY, Tang HT, Jin YC, Li WQ, YuSun, PingFeng, Sun XJ, Xia ZF. Hydrogen inhalation ameliorates lipopolysaccharide-induced acute lung injury in mice. International immunopharmacology. 2011;11:2130-2137

122.  Schoenfeld MP, Ansari RR, Zakrajsek JF, Billiar TR, Toyoda Y, Wink DA, Nakao A. Hydrogen therapy may reduce the risks related to radiation-induced oxidative stress in space flight. Medical hypotheses. 2011;76:117-118

123.  Shen L, Wang J, Liu K, Wang CZ, Wang CT, Wu HW, Sun Q, Sun XJ, Jing H. Hydrogen-rich saline is cerebroprotective in a rat model of deep hypothermic circulatory arrest. Neurochemical research. 2011;36:1501-1511

124.  Song GH, Tian H, Liu J, Zhang HL, Sun XJ, Qin SC. H-2 inhibits tnf-alpha-induced lectin-like oxidized ldl receptor-1 expression by inhibiting nuclear factor kappa b activation in endothelial cells. Biotechnology Letters. 2011;33:1715-1722

125.  Sun HY, Chen L, Zhou WP, Hu LA, Li LA, Tu QQ, Chang YX, Liu Q, Sun XJ, Wu MC, Wang HY. The protective role of hydrogen-rich saline in experimental liver injury in mice. Journal of hepatology. 2011;54:471-480

126.  Sun QA, Cai JM, Liu SL, Liu Y, Xu WG, Tao HY, Sun XJ. Hydrogen-rich saline provides protection against hyperoxic lung injury. Journal of Surgical Research. 2011;165:E43-E49

127.  Sun QA, Cai JM, Zhou JR, Tao HY, Zhang JH, Zhang W, Sun XJ. Hydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity. Critical care medicine. 2011;39:765-769

128.  Terasaki Y, Ohsawa I, Terasaki M, Takahashi M, Kunugi S, Kang DD, Urushiyama H, Amenomori S, Kaneko-Togashi M, Kuwahara N, Ishikawa A, Kamimura N, Ohta S, Fukuda Y. Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress. American Journal of Physiology-Lung Cellular and Molecular Physiology. 2011;301:L415-L426

129.  Ueda Y, Kojima T, Oikawa T. Hippocampal gene network analysis suggests that coral calcium hydride may reduce accelerated senescence in mice. Nutrition Research. 2011;31:863-872

130.  Wang C, Li JA, Liu QA, Yang R, Zhang JH, Cao YP, Sun XJ. Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of jnk and nf-kappa b activation in a rat model of amyloid-beta-induced alzheimer's disease. Neuroscience letters. 2011;491:127-132

131.  Wang F, Yu GA, Liu SY, Li JB, Wang JF, Bo LL, Qian LR, Sun XJ, Deng XM. Hydrogen-rich saline protects against renal ischemia/reperfusion injury in rats. Journal of Surgical Research. 2011;167:E339-E344

132.  Weis SN, Schunck RVA, Pettenuzzo LF, Krolow R, Matte C, Manfredini V, Peralbad MDR, Vargas CR, Dalmaz C, Wyse ATS, Netto CA. Early biochemical effects after unilateral hypoxia-ischemia in the immature rat brain. International Journal of Developmental Neuroscience. 2011;29:115-120

133.  Yan HX, Kinjo T, Tian HZ, Hamasaki T, Teruya K, Kabayama S, Shirahata S. Mechanism of the lifespan extension of caenorhabditis elegans by electrolyzed reduced water-participation of pt nanoparticles. Bioscience Biotechnology and Biochemistry. 2011;75:1295-1299

134.  Yang X, Guo L, Sun X, Chen X, Tong X. Protective effects of hydrogen-rich saline in preeclampsia rat model. Placenta. 2011;32:681-686

135.  Yoon KS, Huang XZ, Yoon YS, Kim SK, Song SB, Chang BS, Kim DH, Lee KJ. Histological study on the effect of electrolyzed reduced water-bathing on uvb radiation-induced skin injury in hairless mice. Biological & pharmaceutical bulletin. 2011;34:1671-1677

136.  Yoon YS, Kim DH, Kim SK, Song SB, Uh Y, Jin D, Qi XF, Teng YC, Lee KJ. The melamine excretion effect of the electrolyzed reduced water in melamine-fed mice. Food and Chemical Toxicology. 2011;49:1814-1819

137.  Yu JG, Zhou RR, Cai GJ. From hypertension to stroke: Mechanisms and potential prevention strategies. Cns Neuroscience & Therapeutics. 2011;17:577-584

138.  Yu P, Wang ZX, Sun XJ, Chen XH, Zeng SY, Chen L, Li SR. Hydrogen-rich medium protects human skin fibroblasts from high glucose or mannitol induced oxidative damage. Biochemical and biophysical research communications. 2011;409:350-355

139.  Zhang YF, Sun QA, He B, Xiao JA, Wang ZN, Sun XJ. Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion. International journal of cardiology. 2011;148:91-95

140.  Zhao LQ, Zhou CF, Zhang JA, Gao F, Li BL, Chuai YH, Liu C, Cai JM. Hydrogen protects mice from radiation induced thymic lymphoma in balb/c mice. International Journal of Biological Sciences. 2011;7:297-300

141.  Zheng XF, Sun XJ, Xia ZF. Hydrogen resuscitation, a new cytoprotective approach. Clinical and Experimental Pharmacology and Physiology. 2011;38:155-163

142.  Zhu WJ, Nakayama M, Mori T, Nakayama K, Katoh J, Murata Y, Sato T, Kabayama S, Ito S. Intake of water with high levels of dissolved hydrogen (h-2) suppresses ischaemia-induced cardio-renal injury in dahl salt-sensitive rats. Nephrology Dialysis Transplantation. 2011;26:2112-2118

143.  Abe T, Li XK, Yazawa K, Hatayama N, Xie L, Sato B, Kakuta Y, Tsutahara K, Okumi M, Tsuda H, Kaimori J, Isaka Y, Natori M, Takahara S, Nonomura N. Hydrogen-rich university of wisconsin solution attenuates renal cold ischemia-reperfusion injury. Transplantation. 2012;94:14-21

144.  Anzai K, Ban N, Ozawa T, Tokonami S. Fukushima daiichi nuclear power plant accident: Facts, environmental contamination, possible biological effects, and countermeasures. Journal of Clinical Biochemistry and Nutrition. 2012;50:2-8

145.  Betanzos-Lara S, Liu Z, Habtemariam A, Pizarro AM, Qamar B, Sadler PJ. Organometallic ruthenium and iridium transfer-hydrogenation catalysts using coenzyme nadh as a cofactor. Angewandte Chemie-International Edition. 2012;51:3897-3900

146.  Boros M, Ghyczy M, Erces D, Varga G, Tokes T, Kupai K, Torday C, Kaszaki J. The anti-inflammatory effects of methane. Critical care medicine. 2012;40:1269-1278

147.  Carbonero F, Benefiel AC, Gaskins HR. Contributions of the microbial hydrogen economy to colonic homeostasis. Nature Reviews Gastroenterology & Hepatology. 2012;9:504-518

148.  Chuai YH, Gao F, Li BL, Zhao LQ, Qian LR, Cao F, Wang L, Sun XJ, Cui JG, Cai JM. Hydrogen-rich saline attenuates radiation-induced male germ cell loss in mice through reducing hydroxyl radicals. Biochemical Journal. 2012;442:49-56

149.  Chuai YH, Qian LR, Sun XJ, Cai JM. Molecular hydrogen and radiation protection. Free radical research. 2012;46:1061-1067

150.  Chuai YH, Shen JL, Qian LR, Wang YC, Huang YC, Gao F, Cui JG, Ni J, Zhao LQ, Liu SL, Sun XJ, Li BL, Cai JM. Hydrogen-rich saline protects spermatogenesis and hematopoiesis in irradiated balb/c mice. Medical Science Monitor. 2012;18:BR89-BR94

151.  Doi N, Hoshi Y, Itokawa M, Yoshikawa T, Ichikawa T, Arai M, Usui C, Tachikawa H. Paradox of schizophrenia genetics: Is a paradigm shift occurring? Behavioral and Brain Functions. 2012;8

152.  Domoki F, Zolei D, Olah O, Toth-Szuki V, Hopp B, Bari F, Smausz T. Evaluation of laser-speckle contrast image analysis techniques in the cortical microcirculation of piglets. Microvascular research. 2012;83:311-317

153.  Ekuni D, Tomofuji T, Endo Y, Kasuyama K, Irie K, Azuma T, Tamaki N, Mizutani S, Kojima A, Morita M. Hydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model. Archives of oral biology. 2012;57:1615-1622

154.  Feng M, Wang XH, Yang XB, Xiao Q, Jiang FG. Protective effect of saturated hydrogen saline against blue light-induced retinal damage in rats. International journal of ophthalmology. 2012;5:151-157

155.  Fujita K, Yamafuji M, Nakabeppu Y, Noda M. Therapeutic approach to neurodegenerative diseases by medical gases: Focusing on redox signaling and related antioxidant enzymes. Oxidative Medicine and Cellular Longevity. 2012

156.  Ge PF, Zhao JW, Li SL, Ding YC, Yang FW, Luo YN. Inhalation of hydrogen gas attenuates cognitive impairment in transient cerebral ischemia via inhibition of oxidative stress. Neurological research. 2012;34:187-194

157.  Ghanizadeh A. Hydrogen as a novel hypothesized emerging treatment for oxidative stress in autism. European Review for Medical and Pharmacological Sciences. 2012;16:1313-1314

158.  Hardeland R. Hydrogen therapy: A future option in critical care? Critical care medicine. 2012;40:1382-1383

159.  Hong Y, Guo SX, Chen S, Sun CR, Zhang JM, Sun XJ. Beneficial effect of hydrogen-rich saline on cerebral vasospasm after experimental subarachnoid hemorrhage in rats. Journal of neuroscience research. 2012;90:1670-1680

160.  Hou ZG, Luo W, Sun XJ, Hao SY, Zhang Y, Xu FF, Wang ZC, Liu BY. Hydrogen-rich saline protects against oxidative damage and cognitive deficits after mild traumatic brain injury. Brain research bulletin. 2012;88:560-565

161.  Huang LN, Zhao SH, Zhang JH, Sun XJ. Hydrogen saline treatment attenuates hyperoxia-induced retinopathy by inhibition of oxidative stress and reduction of vegf expression. Ophthalmic Research. 2012;47:122-127

162.  Ji XT, Tian Y, Xie KL, Liu WP, Qu Y, Fei Z. Protective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress. Journal of Surgical Research. 2012;178:E9-E16

163.  Jiang DP, Wu DZ, Zhang YB, Xu B, Sun XJ, Li ZZ. Protective effects of hydrogen rich saline solution on experimental testicular ischemia-reperfusion injury in rats. Journal of Urology. 2012;187:2249-2253

164.  Kato S, Saitoh Y, Iwai K, Miwa N. Hydrogen-rich electrolyzed warm water represses wrinkle formation against uva ray together with type-i collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes. Journal of Photochemistry and Photobiology B-Biology. 2012;106:24-33

165.  Katsura K, Suda S, Abe A, Kanamaru T, Toda Y, Katayama Y. Brain protection therapy in acute cerebral infarction. Journal of Nippon Medical School. 2012;79:104-110

166.  Kawai D, Takaki A, Nakatsuka A, Wada J, Tamaki N, Yasunaka T, Koike K, Tsuzaki R, Matsumoto K, Miyake Y, Shiraha H, Morita M, Makino H, Yamamoto K. Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice. Hepatology. 2012;56:912-921

167.  Lee JW, Kim JI, Lee YA, Lee DH, Song CS, Cho YJ, Han JS. Inhaled hydrogen gas therapy for prevention of testicular ischemia/reperfusion injury in rats. Journal of pediatric surgery. 2012;47:736-742

168.  Li D, Wang WC. Can hydrogen retard the progression of osteoarthritis? African Journal of Pharmacy and Pharmacology. 2012;6:352-354

169.  Li H, Zhou RH, Liu J, Li Q, Zhang JY, Mu JL, Sun XJ. Hydrogen-rich saline attenuates lung ischemia-reperfusion injury in rabbits. Journal of Surgical Research. 2012;174:E11-E16

170.  Li JJ, Dong YS, Chen HG, Han HZ, Yu YH, Wang GL, Zeng Y, Xie KL. Protective effects of hydrogen-rich saline in a rat model of permanent focal cerebral ischemia via reducing oxidative stress and inflammatory cytokines. Brain research. 2012;1486:103-111

171.  Liu AJ, Zang P, Guo JM, Wang W, Dong WZ, Guo W, Xiong ZG, Wang WZ, Su DF. Involvement of acetylcholine-alpha 7nachr in the protective effects of arterial baroreflex against ischemic stroke. Cns Neuroscience & Therapeutics. 2012;18:918-926

172.  Liu XW, Chen Z, Mao NF, Xie Y. The protective of hydrogen on stress-induced gastric ulceration. International immunopharmacology. 2012;13:197-203

173.  Morinaga H, Sugiyama H, Inoue T, Takiue K, Kikumoto Y, Kitagawa M, Akagi S, Nakao K, Maeshima Y, Miyazaki I, Asanuma M, Hiramatsu M, Makino H. Effluent free radicals are associated with residual renal function and predict technique failure in peritoneal dialysis patients. Peritoneal Dialysis International. 2012;32:453-461

174.  Nagatani K, Wada K, Takeuchi S, Kobayashi H, Uozumi Y, Otani N, Fujita M, Tachibana S, Nawashiro H. Effect of hydrogen gas on the survival rate of mice following global cerebral ischemia. Shock. 2012;37:645-652

175.  Nie W, Tang H, Fang Z, Chen JQ, Chen HL, Xiu QY. Hydrogenase: The next antibiotic target? Clinical Science. 2012;122:575-580

176.  Nishimura N, Tanabe H, Sasaki Y, Makita Y, Ohata M, Yokoyama S, Asano M, Yamamoto T, Kiriyama S. Pectin and high-amylose maize starch increase caecal hydrogen production and relieve hepatic ischaemia-reperfusion injury in rats. British Journal of Nutrition. 2012;107:485-492

177.  Noda K, Tanaka Y, Shigemura N, Kawamura T, Wang YN, Masutani K, Sun XJ, Toyoda Y, Bermudez CA, Nakao A. Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration. Transplant International. 2012;25:1213-1222

178.  Ohno K, Ito M, Ichihara M. Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases. Oxidative Medicine and Cellular Longevity. 2012

179.  Ohta S. Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases. Biochimica Et Biophysica Acta-General Subjects. 2012;1820:586-594

180.  Qian LR, Shen JL, Cai JM. Hydrogen therapy may be an effective and specific novel treatment for aplastic anemia. Medical Science Monitor. 2012;18:HY19-HY22

181.  Qin ZX, Yu P, Qian DH, Song MB, Tan H, Yu Y, Li W, Wang H, Liu J, Wang Q, Sun XJ, Jiang H, Zhu JK, Lu W, Huang L. Hydrogen-rich saline prevents neointima formation after carotid balloon injury by suppressing ros and the tnf-alpha/nf-kappa b pathway. Atherosclerosis. 2012;220:343-350

182.  Qu J, Gan YN, Xie KL, Liu WB, Wang YF, Hei RY, Mi WJ, Qiu JH. Inhalation of hydrogen gas attenuates ouabain-induced auditory neuropathy in gerbils. Acta pharmacologica Sinica. 2012;33:445-451

183.  Qu J, Li X, Wang J, Mi WJ, Xie KL, Qiu JH. Inhalation of hydrogen gas attenuates cisplatin-induced ototoxicity via reducing oxidative stress. International Journal of Pediatric Otorhinolaryngology. 2012;76:111-115

184.  Ren JD, Luo ZL, Tian FZ, Wang Q, Li K, Wang C. Hydrogen-rich saline reduces the oxidative stress and relieves the severity of trauma-induced acute pancreatitis in rats. Journal of Trauma and Acute Care Surgery. 2012;72:1555-1561

185.  Rezende-Neto JB. Editorial critique. Journal of Trauma and Acute Care Surgery. 2012;72:1561-1561

186.  Sakai K, Cho SS, Shibata I, Yoshitomi O, Maekawa T, Sumikawa K. Inhalation of hydrogen gas protects against myocardial stunning and infarction in swine. Scandinavian Cardiovascular Journal. 2012;46:183-188

187.  Sano M. Multifaceted approach to analyzing the pathogenesis of cardiovascular disease. Circulation Journal. 2012;76:2521-2529

188.  Shi JX, Yao F, Zhong CX, Pan XF, Yang Y, Lin Q. Hydrogen saline is protective for acute lung ischaemia/reperfusion injuries in rats. Heart Lung and Circulation. 2012;21:556-563

189.  Shimouchi A, Nose K, Shirai M, Kondo T. Estimation of molecular hydrogen consumption in the human whole body after the ingestion of hydrogen-rich water. In: Wolf M, Bucher HU, Rudin M, VanHuffel S, Wolf U, Bruley DF, Harrison DK, eds. Oxygen transport to tissue xxxiii. 2012:245-250.

190.  Simon AR. Hydrogen-supplemented drinking water, just soda or an elixir of life? Transplant International. 2012;25:1211-1212

191.  Song GH, Tian H, Qin SC, Sun XJ, Yao ST, Zong CL, Luo YY, Liu J, Yu Y, Sang H, Wang XN. Hydrogen decreases athero-susceptibility in apolipoprotein b-containing lipoproteins and aorta of apolipoprotein e knockout mice. Atherosclerosis. 2012;221:55-65

192.  Spulber S, Edoff K, Hong L, Morisawa S, Shirahata S, Ceccatelli S. Molecular hydrogen reduces lps-induced neuroinflammation and promotes recovery from sickness behaviour in mice. PloS one. 2012;7

193.  Sun Q, Kawamura T, Masutani K, Peng XM, Stolz DB, Pribis JP, Billiar TR, Sun XJ, Bermudez CA, Toyoda Y, Nakao A. Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats. Cardiovascular research. 2012;94:144-153

194.  Takeuchi S, Wada K, Nagatani K, Osada H, Otani N, Nawashiro H. Hydrogen may inhibit collagen-induced platelet aggregation: An ex vivo and in vivo study. Internal Medicine. 2012;51:1309-1313

195.  Wang QJ, Zha XJ, Kang ZM, Xu MJ, Huang Q, Zou DJ. Therapeutic effects of hydrogen saturated saline on rat diabetic model and insulin resistant model via reduction of oxidative stress. Chinese medical journal. 2012;125:1633-1637

196.  Wang WL, Li Y, Ren J, Xia F, Li JS, Zhang ZM. Hydrogen rich saline reduces immune-mediated brain injury in rats with acute carbon monoxide poisoning. Neurological research. 2012;34:1007-1015

197.  Wei LH, Ge L, Qin SC, Shi YZ, Du CQ, Du H, Liu LW, Yu Y, Sun XJ. Hydrogen-rich saline protects retina against glutamate-induced excitotoxic injury in guinea pig. Experimental eye research. 2012;94:117-127

198.  Xiang J, Lan R, Tang YP, Chen YP, Cai DF. Apocynum venetum leaf extract attenuates disruption of the blood-brain barrier and upregulation of matrix metalloproteinase-9/-2 in a rat model of cerebral ischemia-reperfusion injury. Neurochemical research. 2012;37:1820-1828

199.  Xiang L, Tan JW, Huang LJ, Jia L, Liu YQ, Zhao YQ, Wang K, Dong JH. Inhalation of hydrogen gas reduces liver injury during major hepatotectomy in swine. World Journal of Gastroenterology. 2012;18:5197-5204

200.  Xiao X, Cai JP, Xu JJ, Wang RB, Cai JM, Liu Y, Xu WG, Sun XJ, Li RP. Protective effects of hydrogen saline on diabetic retinopathy in a streptozotocin-induced diabetic rat model. Journal of Ocular Pharmacology and Therapeutics. 2012;28:76-82

201.  Xie KL, Fu WZ, Xing WB, Li AL, Chen HG, Han HZ, Yu YH, Wang GL. Combination therapy with molecular hydrogen and hyperoxia in a murine model of polymicrobial sepsis. Shock. 2012;38:656-663

202.  Xie KL, Yu YH, Huang Y, Zheng LN, Li JP, Chen HG, Han HZ, Hou LC, Gong G, Wang GL. Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis. Shock. 2012;37:548-555

203.  Xie YJ, Mao Y, Lai DW, Zhang W, Shen WB. H-2 enhances arabidopsis salt tolerance by manipulating zat10/12-mediated antioxidant defence and controlling sodium exclusion. PloS one. 2012;7

204.  Xu Z, Zhou JR, Cai JM, Zhu Z, Sun XJ, Jiang CL. Anti-inflammation effects of hydrogen saline in lps activated macrophages and carrageenan induced paw oedema. Journal of Inflammation-London. 2012;9

205.  Yagami T, Yamamoto Y, Kohma H, Takase K. Arachidonate cascade in the intensive insulin therapy for critically ill patients with sepsis: Roles of prostaglandins on hyperglycemia-impaired immunity. Letters in Drug Design & Discovery. 2012;9:557-567

206.  Yang YY, Li BL, Liu C, Chuai YH, Lei JX, Gao F, Cui JG, Sun D, Cheng Y, Zhou CF, Cai JM. Hydrogen-rich saline protects immunocytes from radiation-induced apoptosis. Medical Science Monitor. 2012;18:BR144-BR148

207.  Yoshida A, Asanuma H, Sasaki H, Sanada S, Yamazaki S, Asano Y, Shinozaki Y, Mori H, Shimouchi A, Sano M, Asakura M, Minamino T, Takashima S, Sugimachi M, Mochizuki N, Kitakaze M. H-2 mediates cardioprotection via involvements of k-atp channels and permeability transition pores of mitochondria in dogs. Cardiovascular Drugs and Therapy. 2012;26:217-226

208.  Yu YS, Zheng H. Chronic hydrogen-rich saline treatment reduces oxidative stress and attenuates left ventricular hypertrophy in spontaneous hypertensive rats. Molecular and cellular biochemistry. 2012;365:233-242

209.  Zhan Y, Chen CH, Suzuki H, Hu Q, Zhi XG, Zhang JH. Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats. Critical care medicine. 2012;40:1291-1296

210.  Zhang JY, Liu C. Letter to the editor on "profiling molecular changes induced by hydrogen treatment of lung allografts prior to procurement". Biochemical and biophysical research communications. 2012;427:227-227

211.  Zhang JY, Liu C, Tai MH, Qu K. Effect of hydrogen gas on the survival rate of mice following global cerebral ischemia. Shock 37(6):645-652, 2012. Shock. 2012;38:444-444

212.  Zhang JY, Liu C, Zhou L, Qu K, Wang RT, Tai MH, Lei J, Wu QF, Wang ZX. A review of hydrogen as a new medical therapy. Hepato-Gastroenterology. 2012;59:1026-1032

213.  Zheng H, Yu YS. Chronic hydrogen-rich saline treatment attenuates vascular dysfunction in spontaneous hypertensive rats. Biochemical pharmacology. 2012;83:1269-1277

214.  Zhou J, Chen Y, Huang GQ, Li J, Wu GM, Liu L, Bai YP, Wang J. Hydrogen-rich saline reverses oxidative stress, cognitive impairment, and mortality in rats submitted to sepsis by cecal ligation and puncture. Journal of Surgical Research. 2012;178:390-400

215.  Zhou J, Wu PF, Wang F, Chen JG. Targeting gaseous molecules to protect against cerebral ischaemic injury: Mechanisms and prospects. Clinical and Experimental Pharmacology and Physiology. 2012;39:566-576

216.  Zhou Y, Zheng H, Ruan F, Chen X, Zheng G, Kang M, Zhang Q, Sun X. Hydrogen-rich saline alleviates experimental noise-induced hearing loss in guinea pigs. Neuroscience. 2012;209:47-53

217.  Zhuang Z, Zhou ML, You WC, Zhu L, Ma CY, Sun XJ, Shi JX. Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits. BMC neuroscience. 2012;13

218.  Zong CL, Song GH, Yao ST, Li LQ, Yu Y, Feng L, Guo SD, Luo T, Qin SC. Administration of hydrogen-saturated saline decreases plasma low-density lipoprotein cholesterol levels and improves high-density lipoprotein function in high-fat diet-fed hamsters. Metabolism-Clinical and Experimental. 2012;61:794-800

219.  Amitani H, Asakawa A, Cheng KC, Amitani M, Kaimoto K, Nakano M, Ushikai M, Li YX, Tsai ML, Li JB, Terashi M, Chaolu H, Kamimura R, Inui A. Hydrogen improves glycemic control in type1 diabetic animal model by promoting glucose uptake into skeletal muscle. PloS one. 2013;8

220.  Cai WW, Zhang MH, Yu YS, Cai JH. Treatment with hydrogen molecule alleviates tnf alpha-induced cell injury in osteoblast. Molecular and cellular biochemistry. 2013;373:1-9

221.  Wang WL, Tian L, Li Y, Wang XJ, Xia F, Li L, Li JS, Zhang ZM. Effects of hydrogen-rich saline on rats with acute carbon monoxide poisoning. Journal of Emergency Medicine. 2013;44:107-115

222.  Yonamine R, Satoh Y, Kodama M, Araki Y, Kazama T. Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice. Anesthesiology. 2013;118:105-113

223.  Zhang DQ, Zhu JH, Chen WC. Acarbose: A new option in the treatment of ulcerative colitis by increasing hydrogen production. African Journal of Traditional Complementary and Alternative Medicines. 2013;10:166-169

 

 



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