A Yale research team has designed a system to modify, or edit, multiple genes in the genome simultaneously, while also minimizing unintended effects. The gene-editing "toolbox" provides a user-friendly solution that scientists can apply to research on cancer and other disciplines, the researchers said. The study was published on July 26 in Nucleic Acids Research. With modern genetic engineering techniques, such as the recently developed CRISPR technologies, researchers can edit genes in experiments. This rapidly evolving field allows researchers to study important disease-related genes and may ultimately allow them to treat genetic diseases by making edits in specific sites of the human genome.