博文
科学家已找到癌症的“阿基里斯之踵”
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Researchers have developed a method to track down the “Achilles' heel” of cancer cells that they believe could be used to design an effective personalized cancer treatment. They hope to test it in two years' time, according to a study published March 3 in the journal Science.
Researchers from MIT, Harvard University and University College London have found a way to locate unique markings within a cancerous tumor that they believe could allow the body’s immune system to target the disease.
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
http://science.sciencemag.org/content/early/2016/03/02/science.aaf1490
Scientists Find Cancer's 'Achilles' Heel'
Researchers have developed a method to track down the “Achilles' heel” of cancer cells that they believe could be used to design an effective personalized cancer treatment. Researchers from MIT, Harvard University and University College London have found a way to locate unique markings within a cancerous tumor that they believe could allow the body’s immune system to target the disease. In the past, efforts at developing vaccines like this-ones that guide the immune system to eradicating tumors-have largely failed.
Newsweek
Health
Scientists Just Made a Major Breakthrough in Personalized Cancer Treatment
Scientists at the University College London (UCL) have made a major breakthrough that may further cement so-called immunotherapies’ status as the most promising advance in cancer treatments in years. The cancer immunotherapy treatment space has blasted off in popularity over the last several years and led to a flurry of innovation in the biopharma sphere. Companies like Merck and Bristol-Myers Squibb introduced the pioneering drugs in this treatment category with their medications Keytruda and Opdivo, respectively.
Fortune
- Cancer's 'Achilles Heel' Discovery Hailed as BreakthroughNewsmaxNew cancer research breakthroughFox Business Videos
An international scientific team has discovered cancer's 'Achilles heel' ... system to target and destroy cancer cells by identifying specific ...
Scientists have found what they’re calling the “Achilles heel” of cancer, ... identify and target the tumor antigens that are in every cancer cell, ...
Scientists 'find cancer's Achilles heel' By James Gallagher Health editor, BBC News website. ... it's how many of the cancer cells have them," he said.
Cancer development, progression, and metastasis are multistep processes. Accumulating evidence suggests that reactive oxygen species (ROS) are critically involved in ...
Researchers have developed a method to track down the “Achilles' heel” of cancer cells that they believe could be used to design an effective personalized cancer ...
Sep 15, 2015 · ... a leader of Dana-Farber/Boston Children’s who serves as chairman of pediatric oncology at the Dana-Farber Cancer ... Achilles’ heel of sickle cell ...
1 Tozluoğlu, M et al, Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions (2013) Nature Cell Biology.
https://blog.sciencenet.cn/blog-39731-960536.html
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