匹兹堡大学新型冠状病毒（SARS-CoV-2）疫苗来取得进展

COVID-19 vaccine candidate shows promise, research shows

https://www.sciencedaily.com/releases/2020/04/200402144508.htm

Journal Reference:

1. Eun Kima, Geza Erdosb, Shaohua Huanga, Thomas W. Kennistona, Stephen C. Balmertb,Cara Donahue Careyb, V. Stalin Raje,1, Michael W. Epperlyc, William B. Klimstrad,Bart L. Haagmanse, Emrullah Korkmazb,f, Louis D. Falo Jr.b,f,g,h,*, Andrea Gambotto. Microneedle array delivered recombinant coronavirus vaccines:Immunogenicity and rapid translational development. EBioMedicine, 2020 DOI: 10.1016/j.ebiom.2020.102743

==========================

一个国际研究小组发现了一种试验药物，可以有效地阻断SARS-CoV-2来感染宿主的细胞

“我们的新研究提供了非常需要的直接证据，证明一种即将在欧洲生物技术公司Apeiron Biologics进行临床试验的药物——APN01（人类重组可溶性血管紧张素转换酶2——(human recombinant soluble angiotensin-converting enzyme 2，hrsACE2）——作为COVID-19的抗病毒治疗是有用的，”Art Slutsky博士说

 Trial drug can significantly block early stages of COVID-19 in engineered human tissues

https://www.sciencedaily.com/releases/2020/04/200402144526.htm

Journal Reference:

1. Vanessa Monteil, Hyesoo Kwon, Patricia Prado, Astrid Hagelkrüys, Reiner A. Wimmer, Martin Stahl, Alexandra Leopoldi, Elena Garreta, Carmen Hurtado Del Pozo, Felipe Prosper, J.p. Romero, Gerald Wirnsberger, Haibo Zhang, Arthur S. Slutsky, Ryan Conder, Nuria Montserrat, Ali Mirazimi, Josef M. Penninger. Inhibition of SARS-CoV-2 infections in engineered human tissues using clinical-grade soluble human ACE2. Submitted to Cell, 2020 DOI: 10.1016/j.cell.2020.04.004