原型智能手机应用程序可以帮助家长发现儿童眼部疾病的早期迹象

贝勒大学一名研究人员开发的智能手机应用程序原型已经通过了第一次大规模测试，该应用程序旨在帮助家长在孩子身上发现各种眼部疾病的早期征兆，如视网膜母细胞瘤（一种侵袭性的儿童眼癌）。

Prototype smartphone app can help parents detect early signs of eye disorders in children

https://www.sciencedaily.com/releases/2019/10/191003164154.htm

Journal Reference:

1. Micheal C. Munson, Devon L. Plewman, Katelyn M. Baumer, Ryan Henning, Collin T. Zahler, Alexander T. Kietzman, Alexandra A. Beard, Shizuo Mukai, Lisa Diller, Greg Hamerly, Bryan F. Shaw. Autonomous early detection of eye disease in childhood photographs. Science Advances, 2019; 5 (10): eaax6363 DOI: 10.1126/sciadv.aax6363

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一种新型抗癌分子

研究人员发明的一种新型抗癌分子在各种癌症类型的临床前模型中显示了治疗活性。线粒体分裂因子（mitochondrial fission factor，MFF）在癌症中高表达，并与电压依赖性阴离子通道-1（voltage-dependent anion channel-1，VDAC1）相互作用，这是线粒体细胞死亡的关键调节因子，以维持肿瘤细胞的存活。体外破坏MFF-VDAC1复合物导致癌细胞死亡，指明了潜在治疗目标的方向。

Targeting regulator of mitochondrial cell death delivers anticancer activity

https://www.sciencedaily.com/releases/2019/10/191003114026.htm

Journal Reference:

1. Jae Ho Seo, Young Chan Chae, Andrew V Kossenkov, Yu Geon Lee, Hsin-Yao Tang, Ekta Agarwal, Dmitry I Gabrilovich, Lucia R. Languino, David W. Speicher, Prashanth K. Shastrula, Alessandra Maria Storaci, Stefano Ferrero, Gabriella Gaudioso, Manuela Caroli, Davide Tosi, Massimo Giroda, Valentina Vaira, Vito W Rebecca, Meenhard Herlyn, Min Xiao, Dylan Fingerman, Alessandra Martorella, Emmanuel Skordalakes, Dario C. Altieri. MFF REGULATION OF MITOCHONDRIAL CELL DEATH IS A THERAPEUTIC TARGET IN CANCER. Cancer Research, 2019; canres.1982.2019 DOI: 10.1158/0008-5472.CAN-19-1982