一个国际团队已经发现了在细胞水平上战胜肥胖的潜力，这是首次发现一种复杂的、几乎不被理解的受体类型，当被激活时，它能阻断饥饿。

Characterizing 'keyhole' is first step to fighting obesity at cellular level

https://www.sciencedaily.com/releases/2018/04/180418141501.htm

1. Zhenlin Yang, Shuo Han, Max Keller, Anette Kaiser, Brian J. Bender, Mathias Bosse, Kerstin Burkert, Lisa M. Kögler, David Wifling, Guenther Bernhardt, Nicole Plank, Timo Littmann, Peter Schmidt, Cuiying Yi, Beibei Li, Sheng Ye, Rongguang Zhang, Bo Xu, Dan Larhammar, Raymond C. Stevens, Daniel Huster, Jens Meiler, Qiang Zhao, Annette G. Beck-Sickinger, Armin Buschauer, Beili Wu. Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor. Nature, 2018; DOI: 10.1038/s41586-018-0046-x