通过研究患者结肠直肠癌，一个研究小组鉴了一个由Ras基因突变产生的完整的蛋白质，RAS基因是人类癌症细胞中的第一个癌症基因。这一发现为目前被认为是找到“无药可及”结肠直肠癌基因治疗的新靶点打开大门。

Top-down approach gets to the bottom of cancer

https://www.sciencedaily.com/releases/2018/04/180417115639.htm

1. Ioanna Ntai, Luca Fornelli, Caroline J. DeHart, Josiah E. Hutton, Peter F. Doubleday, Richard D. LeDuc, Alexandra J. van Nispen, Ryan T. Fellers, Gordon Whiteley, Emily S. Boja, Henry Rodriguez, Neil L. Kelleher. Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk. Proceedings of the National Academy of Sciences, 2018; 115 (16): 4140 DOI: 10.1073/pnas.1716122115

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农业经济学家希望更多地了解热带地区粮食生产的生产率

The 'bread basket' of the tropics? Study explores tropical grain production

https://www.sciencedaily.com/releases/2018/04/180417130109.htm

1. Peter Goldsmith et al. The productivity of tropical grain production. International Journal of Agricultural Management, 2018 DOI: 10.5836/ijam/2017-06-90

2.