寿命的遗传基础知之甚少。大多数研究都是针对短命动物进行的，目前还不清楚这些见解是否转移到长寿的哺乳动物如人类身上。通过比较长命和短命啮齿类动物的基因，研究人员已经发现了一些可能影响哺乳动物长寿和健康老化的新基因。

Old and healthy: Researchers find novel genes for longevity in mammals

https://www.sciencedaily.com/releases/2018/04/180404095529.htm

1. Arne Sahm, Martin Bens, Karol Szafranski, Susanne Holtze, Marco Groth, Matthias Görlach, Cornelis Calkhoven, Christine Müller, Matthias Schwab, Johann Kraus, Hans A. Kestler, Alessandro Cellerino, Hynek Burda, Thomas Hildebrandt, Philip Dammann, Matthias Platzer. Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. PLOS Genetics, 2018; 14 (3): e1007272 DOI: 10.1371/journal.pgen.1007272